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Background: Clinical tools to diagnose the early changes of osteoarthritis (OA) that occur in the articular cartilage are lacking. Objectives: We sought to identify and quantify a novel cartilage oligomeric matrix protein (COMP) neoepitope in the synovial fluid from the joints of healthy horses and those with different stages of OA. Study design: In vitro quantitative proteomics and assay developm
In the study of insect neuroanatomy, three-dimensional (3D) reconstructions of neurons and neuropils have become a standard technique. As images have to be obtained from whole-mount brain preparations, pigmentation on the brain surface poses a serious challenge to imaging. In insects, this is a major problematic in the first visual neuropil of the optic lobe, the lamina, which is obstructed by the
The results of a search for pair production of the lighter scalar partners of top quarks ((t) over bar (1)) in 2.05 fb(-1) of pp collisions at root s = 7 TeV using the ATLAS experiment at the LHC are reported. Scalar top quarks are searched for in events with two same flavour opposite-sign leptons (e, mu) with invariant mass consistent with the Z boson mass, large missing transverse momentum and j
Populärvetenskaplig sammanfattning Morgondagens energi Vind-, och vattenkraft tillsammans med solenergi är de enda energikällorna vi har som inte leder till avfall som ökar växthuseffekt eller avfall som vi inte kan göra oss av (från t ex kärnkraftverk). Men solpanelerna som finns idag för kommersiellt privat bruk ligger på en effektivitet kring 15%. Att utveckla nya molekyler som kan omvanlda solThe aim of the study was to theoretically investigate if a proton coupled electron transfer (PCET) was feasible for a molecular system consisting of a light harvesting complex, ruthenium(tris-2,`2-bipy)2+, with different organic moieties serving as PCET (proton coupled electron transfer) relays. These light harvesting complexes are also sometimes referred to as dyes. By studying the energy levels
Problem Statement: Company Pie is planning for a new centralised distribution centre, as part of a reorganisation of their distribution network. This entails consolidating volumes from several existing facilities, and another company named Company Rho, when setting up a distribution centre configuration. Company Pie wants a second set of eyes to create a configuration, including operations, and de
Ethylenethiourea (ETU) is of major toxicological concern, since in experimental animal studies, ETU has shown a large spectrum of adverse effects. High occupational exposure can be found among agricultural workers or during manufacturing of ethylenbisdithiocarbamates (EBDC). For the general public, sources of environmental exposure may be residues of ETU in commercial products, food and beverages.
This paper presents a search for a new heavy particle produced in association with a top or antitop quark. Two models in which the new heavy particle is a color singlet or a color triplet are considered, decaying, respectively, to (t)over-barq or tq, leading to a resonance within the t(t)over-bar + jets signature. The full 2011 ATLAS pp collision data set from the LHC (4.7 fb(-1)) is used to searc
Purpose: The excess cardiovascular morbidity associated with schizophrenia is attributed to an interplay between behavioural (physical inactivity, unhealthy diet, substance abuse), genetic and illness related factors, as well as the effects of antipsychotic treatment. Patients have limited access to physical healthcare with less opportunity for cardiovascular risk prevention and treatment programm
Since the discovery of the mesoporous silica material templated by ionic surfactants and the subsequent development of materials templated by non-ionic surfactants and polymers, for example SBA-15, there has been a continuous research effort towards understanding their formation. In situ methodologies, such as Small Angle X-ray Scattering (SAXS), Small Angle Neutron Scattering (SANS), spectroscopi
A search is reported for the pair production of a new quark b' with at least one b' decaying to a Z boson and a bottom quark. The data, corresponding to 2.0 fb(-1) of integrated luminosity, were collected from pp collisions at root s = 7 TeV with the ATLAS detector at the CERN Large Hadron Collider. Using events with a b-tagged jet and a Z boson reconstructed from opposite-charge electrons, the ma
The fecal microbiota of two healthy Swedish infants was monitored over time by terminal restriction fragment length polymorphism (T-RFLP) analysis of amplified 16S rRNA genes. Principal component analysis (PCA) of the T-RFLP profiles revealed that the fecal flora in both infants was quite stable during breast-feeding and a major change occurred after weaning. The two infants had different sets of
Young people with intellectual disabilities in Indonesia face difficulties living up to the financial and social independence criteria of social adulthood. Many will need care- and livelihood support throughout their adult lives. This case study aims to examine how formal and informal social protection for persons with intellectual disabilities is organized in a semi-urban city in Central Java. So
Climate change is posing a threat to the whole world. In some places, prolonged droughts cause problems whereas extreme rainfall causes problems elsewhere. Rotterdam faces increasing threats from the North Sea because of rising sea levels. The areas that are not protected by dikes are the most vulnerable and will be the first to flood. This project focuses on an unprotected area of Rotterdam whic
Hiring of employees is based on the relationship between the temporary work agency, the temporary worker and the hiring in firm. The purpose of the relationship is based on the fulfillment of business' need of flexibility. This paper analyzes the effect of the relationship as regards the hiring in firm's responsibility of the working environment of the temporary agency worker. The point of
Sodium stearoyl-2 lactylate (SSL) lipid surfactant molecules specifically bind partially hydrolysed oat proteins in aqueous medium and significantly enhance the dispersion stability of oat cereal preparations. The proposed complexation is composition dependent and a greater understanding of the role of both oat proteins and lipid surfactant in the effect was gained with data from high performance
Popular Abstract in Swedish Spraytorkning är ett vanligt sätt att tillverka partiklar från en lösning. Genom att finfördela lösningen med hjälp av gas i ett spraymunstycke bildas miljontals små vätskedroppar, som blandas med varm torkgas i en torkkammare. Då avdunstar vätskan och fasta, torra partiklar bildas. Tekniken kan användas för att tillverka inhalationspartiklar för användning som läkemedeThe interest in spray drying for production of inhalable particles has grown considerably since the late 1980s. However, which process variables that control degradation and the solid state properties have not been subject to extensive research. This thesis deals with how important characteristics of inhalation particles can be controlled, i.e. particle size, morphology, degradation and crystalli
RATIONALE AND OBJECTIVES: We wanted to improve determination of the glomerular filtration rate (GFR) with plasma clearance techniques because the alternative-renal clearance techniques-may involve inaccurate urine sampling or risk of urinary tract infection when bladder catheterization becomes necessary. Therefore, we compared the renal and plasma clearances of iohexol and chromium-51-ethylenediam
Receptors for the neurotransmitter and neuroendocrine peptides, vasoactive intesinal peptide (VIP) and secretin, both belong to the Type B subfamily of G-protein-coupled receptors. This group is evolutionally as well as structurally distinct from the much larger Type A, or rhodopsin-type, subfamily. We have mapped the ligand-activating epitopes of the human VIP1 receptor by the use of hybrid recep
