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Peptide binding to HLA molecules is a critical step in induction and regulation of T-cell mediated immune responses. Because of combinatorial complexity of immune responses, systematic studies require combination of computational methods and experimentation. Most of available computational predictions are based on discriminating binders from non-binders based on use of suitable prediction threshol
A regulation on nutrition and health claims made on foods was introduced in the European Union in 2007. This Regulation provides opportunities for the use of health claims on foods in Europe, including reduction of disease risk claims. The Regulation will be fully implemented by January 2010. A community list of permitted and rejected claims will be established and made available to the public. So
A new frequency offset tracking approach for OFDM has been addressed. Two-dimensional pilot-symbol assisted modulation (2D-PSAM) is employed in coherent OFDM for channel estimation and it is based on inserting known symbols spread out through the 2D time-frequency grid. We show that these scattered symbols can also be employed to perform frequency synchronization. Maximum likelihood estimation has
Current human-induced climate variability is linked to past economic patterns that are responsible for the majority of greenhouse gas emissions. If climate change is to be effectively addressed, solutions thereof will necessarily affect global economy. International trade has become one of the pillars of the global economic system. In this light an overlap of climate change policies and the multil
Embedded First-InFirst-Out (FIFO) memories are increasingly used in many IC designs.We have created a new full-custom embedded FIFO module withasynchronous read and write clocks, which is at least a factor twosmaller and also faster than SRAM-based and standard-cell-basedcounterparts. The detection qualities of the FIFO test for bothhard and weak resistive shorts and opens have been analyzed by an
New calorimetric methods for direct measurement of solubility and solvent activity are presented. The classical role of calorimetry for measurements of enthalpic parameters is abandoned and the technique is instead used for assessing thermodynamic quantities related to the chemical potential of a substance in a solution. Isothermal calorimetry is here employed as a general analytical method where
In this paper, robotic sensor fusion of acceleration and force measurement is considered. We discuss the problem of using accelerometers close to the end-effectors of robotic manipulators and how it may improve the force control performance. We introduce a new model-based observer approach to sensor fusion of information from various different sensors. During contact transition, accelerometers and
Staff from Instituto de Astrofisica de Canarias, Lund Observatory,Physics Department and Larmor Research Institute at Galway, and TuorlaObservatory is collaborating on studies for a 50 m optical and infraredtelescope. The telescope concepts are based on the work on extremelylarge telescopes carried out during 1991-2000 at Lund Observatory, andon the experience from the 10.4 m segmented Grantecan t
This thesis discusses some of the fundamental requirements needed to be fulfilled when constructing a low temperature scanning tunnelling microscope (STM). Three different designs, two non-vacuum and one ultra-high vacuum (UHV), based on either inertial-mass or novel stepper motor principles are presented. The selection rules that forms the basis for designs are discussed in terms of thermophysica
This paper reports a comparison of soft and hard piezoceramic transducer materials used for ultrasonic particle trapping in a microfluidic bioanalytical platform. The investigation is made with the objective to obtain high acoustic forces with a minimum of temperature increase. Themperature is a critical parameter for bioassays and most often need to be kept below a certain level to allow handling
