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This study evaluated the role of endogenous and exogenous annexin A1 (AnxA1) in the activation of the NLRP3 inflammasome in isolated peritoneal neutrophils. C57BL/6 wild-type (WT) and AnxA1 knockout mice (AnxA1-/-) received 0.3% carrageenan intraperitoneally and, after 3 h, the peritoneal exudate was collected. WT and AnxA1-/- neutrophils were then stimulated with lipopolysaccharide, followed by t
The Ph.D. dissertation consists of three connected, yet independent research articles, which focus on the implementation of circular economy principles in public procurement. Motivated by a curiosity for dynamics in processes of implementation I chose to investigate how actors related to processes of public procurement can implement the circular economy principles as a default. The aim of the diss
This article examines the ever-actual desire to visualise and materialise thought-images in a historical perspective. The interest for research into thought imagery,and of visual proof production of thoughts, coincided with the invention of the camera and culminated somewhere around 1900. Together with other scientific circumstances that appeared up to 1900, such as the experimental psychology mod
Objectives. Oxidized LDL has been attributed a key role in the development of atherosclerosis. Previous studies have demonstrated increased plasma levels of oxidized LDL in patients with established coronary artery disease. The aim of the present study was to investigate if plasma oxidized LDL also predicts risk for development of coronary heart disease (CHD). Design. We used a nested case-contro
Vessel-source pollution is regarded as one of the major sources that harm marine environment. It has become an issue of public concern since 20th century due to a series of oil pollution incidents on the sea. Fortunately, international law has been developed to control this source of pollution taking consideration of the importance of protection and preservation of marine environment and sustainab
Information and communication technologies have acquired contemporary prominence and are being introduced as new and technologically innovative devices for rapid African development, becoming key cornerstones of the development assistance interventions of the European Union and the G8. But the Dot Force Initiative of the G8 and the various ICT for development programmes of the EU display a moderni
BACKGROUND: Efforts to establish the 2015 baseline and monitor early implementation of the UN Sustainable Development Goals (SDGs) highlight both great potential for and threats to improving health by 2030. To fully deliver on the SDG aim of "leaving no one behind", it is increasingly important to examine the health-related SDGs beyond national-level estimates. As part of the Global Burden of Dise
Background: In 2015, six indicators were proposed to evaluate global progress towards access to safe, affordable and timely surgical and anaesthesia care. Although some have been adopted as core global health indicators, none has been evaluated systematically. The aims of this study were to assess the availability, comparability and utility of the indicators, and to present available data and upda
Cities are key actors in reducing both the causes of climate change (mitigation) and its impact (adaptation), and many have developed separate mitigation and adaptation strategies and measures. However, in order to maximize outcomes, both scholars and practitioners are increasingly calling for more integrated and synergetic approaches. Unfortunately, related research remains scarce and fragmented,
Aims To investigate the efficacy of sensor-augmented pump therapy vs. multiple daily injection therapy in patients with suboptimally controlled Type 1 diabetes. Methods In this investigator-initiated multi-centre trial (the Eurythmics Trial) in eight outpatient centres in Europe, we randomized 83 patients with Type 1 diabetes (40 women) currently treated with multiple daily injections, age 18-65 y
PowerPoint Presentation What´s on the horizon? From Big Deals to Offset – Transitioning to Open Access Heiko herwald (30 October, 2019) 1 “In a world deluged by irrelevant information, clarity is power.” Opening sentence of Yuval Noah Harari’s book “21 Lessons for the 21st Century” published in August 2018. http://wcs.webofknowledge.com Year Number of articles Scientific articles 3 Number of scien
https://www.lub.lu.se/en/sites/lub.lu.se.en/files/heiko_herwald_lundonline.pptx - 2026-07-10
What kind of indispensable cognitive ability is needed for intelligence, sociability, communication, and technology to emerge on a habitable planet? My answer is simple: intersubjectivity. I stress the significance of intersubjectivity, of shared cognition, for extraterrestrial intelligence and interstellar communication, and argue that it is in fact crucial and indispensable for any successful in
