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The antiphospholipid syndrome is defined by the presence of antiphospholipid antibodies in blood of patients with thrombosis or fetal loss. There is ample evidence that beta(2)-glycoprotein I (beta(2)GPI) is the major antigen for antiphospholipid antibodies. The autoantibodies recognize beta(2)GPI when bound to anionic surfaces and not in solution. We showed that beta(2)GPI can exist in at least 2

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Arctic sea ice represents an important component of the climate system, and the present reduction of sea ice in the Arctic is of major concern. Despite its importance, little is known about past changes in sea-ice cover and the underlying forcing mechanisms. Here, we use diatom assemblages from a marine sediment core collected from the West Greenland shelf to reconstruct changes in sea-ice cover o

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This Letter presents a search for tb resonances in 1.04 fb(-1) of LHC proton-proton collision data collected by the ATLAS detector at a center-of-mass energy of 7 TeV. Events with a lepton, missing transverse momentum, and two jets are selected and the invariant mass of the corresponding final state is reconstructed. The search exploits the shape of the tb invariant mass distribution compared to t

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Using a direct imaging method, we experimentally investigate the reversal of magnetic islands in a bit-patterned media sample based on a pre-patterned substrate. Due to systematic variation of the island distances in the media, we are able to study the influence of the dipolar interaction on the switching-field distribution of the island ensemble. The experimental findings are explained by an anal

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Popular Abstract in Swedish Basala ganglierna ligger under hjärnbarken i hjärnan och består av grupper av nervceller som är förbundna med varandra och med hjärnbarken. Till dessa grupper av nervceller hör striatum, globus pallidus, subthalamicus-kärnan och substantia nigra. Patologiska förändringar i olika delar av basala ganglierna orsakar många av de symptom som kännetecknar Huntington's och ParHuntington's disease (HD) is a hereditary neurodegenerative disorder presenting with chorea, dementia and extensive striatal neuronal death. The mechanism through which the widely expressed mutant huntingtin mediates striatal neurotoxicity is unknown. Excitotoxicity, i.e. calcium-dependent cell death induced by activation of NMDA receptors, has been hypothesized to play an important role in HD. Ou

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It is shown that under certain regularity conditions on the norm, the functions in a nontrivial invariant subspace of the backward shift operator have meromorphic pseudocontinuations in the Nevanlinna class of the exterior of the unit disk. In addition, we provide a regularity condition which implies that the subspace itself is contained in the Nevanlinna class of the disc.

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Popular Abstract in Swedish Magnetresonanstomografi (MRT) är en metod för framställning av bilder av kroppen och av sjukliga förändringar i kroppen. När metoden introducerades ansågs den utomordentligt goda inbyggda vävnadskontrasten vara tillräcklig för att särskilja olika sjukliga förändringar, speciellt i hjärnan. Det har emellertid visat sig att förmågan att upptäcka sjukliga förändringar är oAims of the study The aims of this study using Gadodiamide injection were to investigate: · Whether Gadodiamide injection was comparable to Gd-DTPA for the enhancement of CNS lesions. · The contrast effect at different field strengths. · The effective time-window for the enhancement of blood-brain barrier damage. · The relations between the concentration of contrast agent and enhancement in p

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Supportive legislation and improving technologies are making bioenergy an increasingly attractive energy source for Europe both economically and environmentally. However, abundant resources remain untapped across many member states in the European Union (EU). The Bioenergy Network of Excellence (NoE) entitled Overcoming Barriers to Bioenergy in Europe is charged with the task to identify critical

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How can qualitative, ethnographic and emotional aspects from probe users be mapped at the same time as they get something meaningful in return? The emphasis is here on intellectual rewards during probe work rather than future good designs that in a long term perspective can be beneficial for the probe user. This case study has elaborated the traditional use of cultural probes [1] with a selection

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Based on a case study of a telecom company’s transition towards more software value in their products, we describe and discuss SCM issues related to when traditional manufacturers go from a “hardware focus” to a mixed product configuration. Although software supply chain is not much discussed in logistics, it seems that logistics/SCM frameworks also fit many software supply issues. A specific soft

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Quality requirements complement functional requirements with information on the target quality levels of software functions or emergent system quality aspects. In release planning the allocation of development effort in further investments into product enhancements, new or enhanced functions are competing with quality improvements for limited resources. When setting balanced quality targets for de

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The Sixth Sense of PR-Experts? An Expert-Novice-Comparison of PR-Problem-Solving and Implications for Public Relations-Pedagogy

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This thesis deals with tools for operational improvement of supply chain performance. The work was aimed at providing knowledge for supply chain developers and practitioners, and identifying and developing tools for improved performance in a supply chain. The investigation was part of a project financed by the European Commission called "Industrial Supply Chain Optimizer" (ISCO). The thesis consis

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Objective: The purpose was to describe and characterize what women with rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA) perceive as important in considering the performance of daily occupations to perceive good health. Methods: By using a phenomenographic research approach with semi-structured interviews with nine women between the ages of 42 and 65 the core category "Being able