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This contribution reports a novel method for cell-supernatant separation inside nanoliter droplets with separation efficiencies for single cells of 100% at flow speeds of 2 mm/s. Cells are focused in nanoliter droplets using bulk acoustic waves before the droplet is split at a bifurcation into a supernatant- and a cell-containing droplet. The method enables upconcentration of cells, cell washing,
DNA carries the genetic code of life, with different conformations associated with different biological functions. Predicting the conformation of DNA from its primary sequence, although desirable, is a challenging problem owing to the polymorphic nature of DNA. We have deployed a host of machine learning algorithms, including the popular state-of-the-art LightGBM (a gradient boosting model), for b
Att vara trans på olika sätt är ingen nödsituation och behöver inte vara dramatiskt. I stället för att enbart reagera i stunden kan politiker, rektorer, lärare, kuratorer, skolsköterskor och andra vuxna skapa en skola där färre spontana lösningar krävs eftersom det finns ett genomtänkt pedagogiskt och administrativt arbete, det som kallas ”whole-of-school approach” (Bartholomaeus & Riggs, 2017Being trans in different ways is not an emergency and does not have to be dramatic. Instead of reacting only in the moment, politicians, principals, teachers, counselors, nurses and other adults can create a school where fewer spontaneous solutions are needed because there is well thought-out pedagogical and administrative work, what is called the 'whole-of-school approach' (Bartholomaeus & Ri
Rapport från ett seminarium sept. 2014 i Manama i Zimbabwe, om diakonens identitet i Lutherska kyrkan i Zimbabwe och i Sverige, två år efter den första vigningen (ordinationen) av diakoner i Evangelical Lutheran Church in Zombabwe.Report from a seminar i Manama in Zimbabwe September 2014: "The Identity of the Deacon in Zimbabwe and Sweden", two years after the first ordination of deacons in the Evangelical Lutheran Church in Zimbabwe (ELCZ).
Aim of the studyRates of bystander CPR are increasing, yet mortality after out-of-hospital cardiac arrest (OHCA) remains high. The aim of this survey was to explore public knowledge and attitudes to CPR. Our hypotheses were that recent CPR training (< 5 years) would be associated with a high-quality response in a case vignette of OHCA with agonal breathing, and associated with an interest to becom
We present a microfluidic system to control the position of particles (polystyrene beads or astrocyte cells) in hydrogel droplets using bulk acoustic standing waves. Droplets comprising hydrogel precursor solution, photoinitiator and (bio-)particles were generated and acoustic forces focused the beads to the droplet center line. Droplets were cross-linked by exposure to UV-light. With the acoustic
The game plan firms must navigate in the quest of competitive advantage which is changing quickly. More and more firms acknowledge that future prosperity depends on achieving the joint goals of economic, environmental and social sustainability. This understanding has resulted in both firms and actors on the financial markets enhancing their focus on environmental, social and governance dimensions
Preeclampsia is a severe pregnancy-related inflammatory disease without an effective treatment. The pathophysiology remains partly unknown. However, an increased inflammatory response and oxidative stress are part of the maternal systemic reaction. Recent data have suggested that dysbiosis of the gut microbiome plays a role in preeclampsia as well as other inflammatory diseases. However, dysbiosis
Popular Abstract in Swedish Ny kunskap gör det möjligt att med hjälp av DNA-information välja ut vilka kvigor/kor som förväntas ge en hög mjölkavkastning, höga halter av mjölkens komponenter och optimala egenskaper för ostproduktion. Denna information kan användas för att bättre anpassa mjölkens sammansättning och processegenskaper med de svenska mejeriernas behov för att på så vis förbättra mjölkMilk genomics is a new area of research that explores the relations between cow genetics and milk characteristics. Identifying the genes controlling compositional and technological traits of milk will give opportunities to select cows for targeted milk production. In this thesis, the impact of different genetic approaches, i.e. quantitative genetic evaluation, single gene effects and genomic selec
Although capacity development has been a key aspect of global aid policy for decades, success is limited. Capacity development is defined as a process, based on a partnership, to develop capacity to achieve a goal. The purpose of this thesis is to increase our understanding of why capacity development does not work as intended, and to inform the discussion on addressing the challenges. Two researc
BackgroundDiagnosing sepsis remains a challenge because of the lack of gold-standard diagnostics. Since there are no simple, broadly accepted criteria for infection, there is a risk of misclassifying sepsis patients (sepsis mimics) among patients with organ failure. The main objective of this study was to investigate the proportion of non-infected patients (sepsis mimics) in ICU patients with pres
‘Flight shame’ describes an unease about the climate implications of air travel, and bears evidence of a change in social norms that have so far associated flying with social status. This paper discusses whether Fridays for Future demonstrations and ensuing flight shame have influenced social norms regarding the desirability of air travel, and whether this is measurable in a decline in air travel,
Progress in the power conversion efficiency of solar cells based on metal-halide perovskite semiconductors has been astonishing for the past years. During their development, transient effects have been observed that gave rise to an uncertainty associated with the determination of device performance from current density-voltage (J-V) measurements. This effect becomes visible in a dependence of the
Syftet med uppsatsen är att utreda den föreslagna kriminaliseringens effekt på Sveriges nuvarande eftergiftsprogram samt undersöka dess effektivitet trots avsaknad av ett kronvittnesförfarande. Vidare avser uppsatsen att undersöka om kriminaliseringens effekter kan påverkas. För att utröna kriminaliseringens effekter har VD: n få en central roll i uppsatsens modell, då det endast är han som berörs
Youth delinquency is an international phenomenon that has an impact on different aspects of society. This study aimed to understand how social workers describe the causes of youth delinquency and their reflections on how they conduct the preventative work at social services. The chosen method was semi-structured interviews with six social workers in Skåne, all with a minimum of one year of working
Under senare år har situationer uppmärksammats där vuxna personer via internet kontaktat personer som de uppfattat som barn i sexuellt syfte, men där motparten i själva verket varit en vuxen person, ofta bakom en profil tillhörande ett fiktivt barn. Sådana situationer aktualiserar frågan om straffrätten bör ingripa mot ett handlande som framstår som klandervärt och typiskt sett syftar till sexuellIn recent years, situations have attracted attention in which adults have contacted persons online whom they believed to be children for sexual purposes, but where the other party was in fact an adult, often behind a profile belonging to a fictitious child. Such situations raise the question of whether criminal law should intervene against conduct that appears blameworthy and is typically aimed at
Purpose: This study aims to computational numerical simulations to clarify and explore the influences of periodic cellular lattice (PCL) morphological parameters – such as lattice structure topology (simple cubic, body-centered cubic, z-reinforced body-centered cubic [BCCZ], face-centered cubic and z-reinforced face-centered cubic [FCCZ] lattice structures) and porosity value ( ) – on the thermal-
This paper explores recent trends in Uzbek labor migration, with a focus on the growing role of the European Union as a destination. While Russia remains the largest host country, ongoing diversification has led to a notable increase in migration to EU member states, particularly for employment. Drawing on official statistics and fieldwork, the study highlights rising numbers of Uzbek migrants in
