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Biological Activities of Natural and Semi-Synthetic Pseudo-Guaianolides: Inhibition of Transcription Factors

Damsin (1) is a natural sesquiterpene lactone (SL) isolated from Ambrosia arborescens Mill., a plant used in the Andes as antiinflammatory medicine. This natural product is an inhibitor of NF- κB, a protein complex that controls the transcription of many genes in mammalian cells, and has a potential for standing model for the development of new anti-cancer lead structures. In order to improve the

Word embeddings on ideology and issues from Swedish parliamentarians’ motions : a comparative approach

Quantitative analysis of large-scale political text data in the form of word embeddings has great potential for systematising differences between political parties. We examine the differences between embeddings obtained from speakers from the two competitors for the PM position in Sweden (Social Democrats and Moderates) over a 30-year period. The goal is to compare how off-the-shelf general pre-tr

Personality and information use in fish: bolder crucian carps learn faster

Abstract Gathering information about the environment is crucial to living organisms as it makes up the foundation upon which decisions are made. In a diverse environment a huge amount of information sources arise. An individual can choose to follow other’s decision (social information use) or to gather its’ own information. Which sources are used and how well they are perceived vary between indi

Motivational Interviewing as Evidence-Based Practice? An Example from Sexual Risk Reduction Interventions Targeting Adolescents and Young Adults

This paper critically examines sexual risk reduction interventions, more specifically how they are evaluated and the implications that this has for sexual health policy. The focus is on motivational interviewing (MI) interventions which aim to promote protective behaviors related to sexual risk on the part of young people. MI has become increasingly popular, largely due to it being a highly flexib

Bottom-up methodology for assessing electrification options for deep decarbonisation of industrial processes

Industrial processes currently account for a signifcant share (25–35 %) of the world’s total energy demand and related emissions. During recent years, the amount of low-carbon electricity from renewable energy sources (such as wind and solar) has increased continuously. Tere is therefore an increasing interestin electrifcation of industrial processes in order to achieve long-term decarbonisation g

Lives of bronze gods and wooden puppets : The material culture of humanoids in Seventeenth-Century Sweden

Living statues and artificial humans have a long cultural history. They are awe-inspiring because they are entangled with existentialist questions about reality, especially as regards the uncertainty of being. This article explores how humanoid material culture in its different forms was involved in the interaction between myriad human and non-human entities in seventeenth-century Sweden and in th