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AIMS: To build a comprehensive biobank integrated in the Swedish Heart Failure Registry (SwedeHF) comprising comprehensive clinomic data, proteomic, transcriptomic and genomic information in combination with clinical and diagnostic characteristics and additional ICD-code registry data.METHODS: Blood and urine samples will be biobanked at SwedeHF registration with an optional second sampling after
This study presents high-fidelity Large Eddy Simulations (LES) of supersonic combustion in a Mach 2 cavity flameholder over the full stable fueling region from 40 to 200 slpm. The simulations employ Finite Rate Chemistry LES with the Z70 ethylene-air mechanism, the Localized Dynamic k-equation model, Partially Stirred Reactor turbulence-chemistry interaction model, conjugate heat transfer, and the
Popular Abstract in SwedishUnder slutet av 1950-talet, ungefär samtidigt med tv:s etablering, innehade Sverige Europarekordet vad gäller antalet biografer. Folk gick på bio som aldrig förr. Biograferna att spela en mycket stor roll för film- och biografkulturens tillgänglighet och spridning. Den här boken handlar om att gå på bio. Genom att gå på bio lärde sig människor att se och uppleva film ochGoing to the Pictures The Cinema as a Meeting Place in the 1940s and 1950s Summary At the end of the 1950s, at roughly the same time as television became established, Sweden had the largest number of cinemas of any country in Europe. People went to the cinema in unprecedented numbers. In 1956 ticket sales in Swedish cinemas reached 80 million. There were palatial cinemas which offered people a f
Popular Abstract in Swedish Hjärt- och kärlsjukdomar är idag den vanligaste dödsorsaken i stora delar av världen för både män och kvinnor. I Sverige är hjärtinfarkt den vanligaste dödsorsaken för kvinnor över 55 år och för män över 45 år. Det vill säga kvinnor drabbas cirka 10 år senare. Tidigare forskning har baserats i huvudsak på män varvid forskning på kvinnor med hjärt- och kärlsjukdomar har Background: Coronary heart disease (CHD) is the sleading cause of mortality in men and women in Western society. Few studies of CHD have been performed on women or with a focus on cardiac risk factors in women’s lives. Results from studies of men have been generalized to women, which may be inappropriate or even dangerous. Aim: The overall aim of this thesis was to describe women’s experience of a
A way to reduce net CO2 emission and circumvent the high particle emissions from compression ignition (CI) engines, while retaining high efficiency, is by utilizing lighter alcohols in the partially premixed combustion (PPC) process. Methanol and ethanol have a very short carbon chain, and form less soot/particulate matter (PM) during combustion compared to diesel fuel. This study analyzes and com
Drainage networks are the basis for segmentation of watersheds, an essential component in hydrological modelling, biogeochemical applications, and resource management plans. With the rapidly increasing availability of topographic information as digital elevation models (DEMs), there have been many studies on DEM-based drainage network extraction algorithms. Most of traditional drainage network ext
Subarctic ecosystems are predicted to experience the fastest responses to climate change on the planet, with dramatically altered vegetation patterns, frost dynamics and hydrological flow paths. The resulting change in dissolved organic carbon (DOC) export to river systems is poorly known, but reports of rising DOC in northern surface waters have led to widespread speculations on a possible climat
Climate change projections show that temperature and precipitation increases can alter the exchange of greenhouse gases between the atmosphere and high latitude landscapes, including their freshwaters. Dissolved organic carbon (DOC) plays an important role in greenhouse gas emissions, but the impact of catchment productivity on DOC release to subarctic waters remains poorly known, especially at re
The density of roots is an important factor influencing the rate and magnitude of landslides. Due to the increased variability in climate, mainly rainfall, Eastern Uganda is severely struck by an increasing number of these mass movements, often with human casualties as one of the negative impacts. The aim of this study is to explore the possibility to estimate the depth and density of the root sys
This statement examines the relation of the resting ECG to its technology. Its purpose is to foster understanding of how the modern ECG is derived and displayed and to establish standards that will improve the accuracy and usefulness of the ECG in practice. Derivation of representative waveforms and measurements based on global intervals are described. Special emphasis is placed on digital signal
OBJECTIVE: To explore the characteristics and outcome of patients after stroke admitted to early supported discharge (ESD) services, and to investigate changes over time. STUDY POPULATIONS: Patients admitted between June 1997 and September 1998 and participating in a follow-up study (n = 87) and all patients admitted in 2005-06 (n = 226). Background populations: All stroke cases in Malmö alive 3 m
Objective The basis for protein synthesis is the genetic code. Many of these proteins will affect intermediary metabolites by acting as enzymes, hormones, or by other actions. The aim of the present study was to assess the relationships of a large number of proteins with endogenous metabolites. Methods Plasma protein levels were measured by the proximity extension assay (PEA) and metabolites by ma
Frågeställningen i uppsatsen är: hur hanterade intagna vistelsen i häktet? Använde de sig av strategier för att uthärda inlåsningen? I så fall vilka? Bakgrunden till uppsatsen är främst den senaste tidens intensiva debatter gällande förhållanden i svenska häkten, diskussioner har bland annat gällt långa häktningstider och stränga restriktioner. Vidare grundar sig mitt intresse främst på ett tidiga
Before performing 177Lu-DOTATATE therapy for neuroendocrine tumors, somatostatin receptor (SSTR) PET imaging is currently used to confirm sufficient tumor SSTR expression, but it also has potential to be used to personalize treatment by predicting absorbed doses to critical organs. This study aims to validate the predictive capability of SSTR PET in anticipating renal absorbed dose in the first cy
Background: Subgroups of adult-onset diabetes, namely severe autoimmune diabetes (SAID), severe insulin-deficient diabetes (SIDD), severe insulin-resistant diabetes (SIRD), and mild obesity-related diabetes (MOD) or mild age-related (MARD) diabetes, have been defined with clinical variables and a machine-learning approach. Our aim was to describe their long-term outcomes and mortality. Methods: In
In comparison to other human cancer types, malignant melanoma exhibits the greatest amount of heterogeneity. After DNA-based detection of the BRAF V600E mutation in melanoma patients, targeted inhibitor treatment is the current recommendation. This approach, however, does not take the abundance of the therapeutic target, i.e., the B-raf V600E protein, into consideration. As shown by immunohistoche
