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A major goal in evolutionary biology is to determine how phenotypic variation arises and is maintained in natural populations. Recent studies examining the morphological, physiological and behavioural differences among discrete colour morphotypes (morphs) have revealed several mechanisms that maintain discrete variation within populations, including frequency-dependence, density-dependence and cor
Human leukocyte antigen class I (HLA-I) presents antigenic peptides to cytotoxic CD8+ T cells (CTLs). This is a pivotal step in the generation of CTL responses. Both the quantity and quality of peptide-HLA-I (pHLA-I) complexes are crucial for CTL responses, but the level of HLA-I expression per se is also directly involved in dictating NK-cell responses. Antigen processing machinery (APM) proteins
Purpose: To evaluate waiting times for first-eye cataract surgery in Sweden following widespread adoption of the Nationell Indikationsmodell for Kataraktextraktion (NIKE) tool for prioritizing patients for cataract surgery. Methods: Waiting times for all first-eye cataract surgeries in Sweden in 2009-2011 were identified from the Swedish National Cataract Register. Waiting times were compared acco
Peptide therapeutics offer advantages in specificity and affinity, yet the potential propensity to self-associate and aggregate poses a challenge for the development of stable oral formulations. This master’s thesis evaluates the utility of the fluorescent dye Thioflavin T as a structural probe to monitor the aggregation of glucagon-like peptide-1 receptor agonists, specifically Liraglutide and Se
Bioenergy is the largest energy source in the Swedish energy system, where it consists mainly of domestic forest-based biomass in the form of residues and by-products. Today, there is a general discussion about the need for changes in national forest management policies and new European Union (EU) directives and regulations for forestry and bioenergy to better fulfil biodiversity and climate targe
Reliable ankle torque measurements are important in rehabilitation, where strength assessments are used to evaluate recovery and guide treatment. Isokinetic dynamometers, such as the Biodex system, are commonly used to provide controlled measurements of joint torque. However, these measurements rely on the ankle being held in a stable and reproducible position. Mechanical play in the ankle-attachm
The increasing use of generative artificial intelligence (GenAI) in advertising has transformed creative production while simultaneously raising concerns about transparency, authenticity and consumer perception. With the growing integration of GenAI into advertising, understanding how consumers respond to AI disclosure has become increasingly important. This study investigates how AI disclosure in
Seminar Date: 2026-06-04 Course: BUSN79, Degree Project in Accounting and Finance Authors: Victor Damberg, Jonatan Svanbom Advisor/Examiner: Diem Nguyen & Reda Moursli Five key words: CDS Spreads, Leverage, Asset Tangibility, Financial Distress Risk, Redeployability Purpose: To investigate whether asset tangibility weakens the positive association between leverage and market-implied
This thesis examines how young people in Finland make sense of profit-oriented drug selling and construct drug dealer identities. Drug use and related harms have increased globally in recent years. In Finland, an increase in minors selling drugs for financial profit has been noticed by the police and a non-governmental youth work organization Children of the Station. The aim of this thesis is to e
Archaeology and archaeological sciences are inherently spatial disciplines. Thus, it is of no surprise that GIS (Geographic Information System) has found its way into archaeological practice, providing an environment for data organisation, analysis and visualisation. Over the past few decades, archaeogeophysics has become an integral part of archaeological practice. The results of these studie
The antibody microarrays have become widespread, but their use for quantitative analyses in clinical samples has not yet been established. We investigated an immunoassay based on nanoporous silicon antibody microarrays for quantification of total prostate-specific-antigen (PSA) in 80 clinical plasma samples, and provide quantitative data from a duplex microarray assay that simultaneously quantifie
A simple and efficient approach for profiling the greenness of high performance liquid chromatography (HPLC) methods is presented. This environmental assessment tool (EAT) takes into consideration the environmental, health and safety issues for all solvents involved in the chromatographic method, and calculates a total score that can be used for comparison of the greenness of different methods. A
PMCA4 is a critical regulator of Ca2+ homeostasis in mammalian cells. While its biological and prognostic relevance in several cancer types has already been demonstrated, only preclinical investigations suggested a metastasis suppressor function in melanoma. Therefore, we studied the expression pattern of PMCA4 in human skin, nevus, as well as in primary and metastatic melanoma using immunohistoch
We report on experimental absolute oscillator strengths for 18 UV lines of Ru II, obtained by combining laser-induced fluorescence measurements of radiative lifetimes and branching fractions from line intensities in a calibrated Fourier-transform spectrum. HST/GHRS observations of the spectrum of the sharp-lined B star chi Lupi contain six of these lines, for which ''astrophysical'' relative f-val
The outgrowth region of the regenerating frog sciatic nerve shows an increased permeability for various drugs, which has been utilized for pharmacological studies of axonal transport. Six days after a bilateral crush lesion, the nerves, including the spinal ganglia, were incubated in a compartmented chamber. Orthograde transport was assessed from the proximodistal distribution and the accumulation
Cancer är idag det näst vanligaste dödsorsaken i världen, där 30% av alla cancerfall bland kvinnor är bröstcancer. En vanlig behandling är bröstbevarande operation, där en bit av bröstet kirurgiskt tas bort. Operationer är både dyrt och har en betydande inverkan på kroppen och för vissa kvinnor krävs en omoperation efter den första operationen. Syftet med detta arbete har varit att undersöka möjliCancer is the second leading cause of death worldwide and 30% of all cancer cases among women are breast cancer. A popular treatment is breast-conserving surgery, where only a part of the breast is surgically removed. Surgery is expensive and has a significant impact on the body, and on some women, a reoperation is needed. The aim of this thesis was to see if there is a possibility to predict whet
