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This report presents basic concepts around resources, resource efficiency and the Circular Economy. The limitations and the opportunities within the Circular Economy are identified and clearly presented. The current policy landscape in the EU as well as in Sweden is thoroughly analysed and a set of policy areas with a significant untapped potential for resource efficiency is identified. The policy
Background: There is an increasing recognition of epidemics of primarily tubular-interstitial chronic kidney disease (CKD) clustering in agricultural communities in low- and middle-income countries (LMICs). Although it is currently unclear whether there is a unified underlying aetiology, these conditions have been collectively termed CKD of undetermined cause (CKDu). CKDu is estimated to have led
For many multivariable problems there are no efficient algorithms for finding solutions. To this day, conventional electronic computers mainly solve problems in a sequential manner. This sequential operation prevents problem-solving within a reasonable time-frame due to superpolynomial, and sometimes even exponential, time complexities. Developing powerful parallel computation techniques has there
In recent years, there has been an increasing interest in innovation studies towards grand challenges, and in how demand-side policy instruments can supplement traditional supply-side policy measures. To contribute to an improved understanding of how demand-side policy requires new governance responses, this article presents a case study of trialling assisted living technologies to address the gra
Introduction The provision of healthcare for patients with inflammatory arthritis occurs in the context of somewhat conflicting targets, values and drivers. Therefore, there is a need for introducing 'value-based healthcare' defined as the value of patient relevant health outcomes in relation to costs. This term is a central part of tomorrow's healthcare sector, especially for rheumatic diseases,
[3H]arachidonic [( 3H]20:4) and [14C]linoleic acid [14C]18:2) were fed to rats in Intralipid or cream. Later (30-240 min) the stomach, small intestine, plasma, and liver were analyzed for radioactivity in different lipid classes. [3H]20:4 and [14C]18:2 were emptied from the stomach and absorbed by the intestine at similar rates. The [3H]20:4:[14C]18:2 ratio of the lipids in the small intestinal wa
Importance: Quality of life is not a standard primary outcome in ablation trials, even though symptoms drive the indication.Objective: To assess quality of life with catheter ablation vs antiarrhythmic medication at 12 months in patients with atrial fibrillation.Design, Setting, and Participants: Randomized clinical trial at 4 university hospitals in Sweden and 1 in Finland of 155 patients aged 30
This study deals with physical education (PE) in secondary school. The purpose of the study is to analyze the relationship between PE in secondary schools and leisure time sports. Questions were directed towards discovering what PE teachers recognise as valuable in their teaching, and how physical education is related to factors that characterize the field of sports. The teaching practice of Physi
This chapter revisits Iver Neumann’s seminal book The Uses of the Other (1999) in order to unpack its assumptions about collective identity formation in world politics. After having situated this work in its contemporary context and pointed to its significance, the chapter tries to demonstrate the extent to which its basic assumptions about collective identity formation replicates those that went
Importance: Prostate cancer, a leading cause of cancer death among men, urgently requires new prevention strategies, which may involve targeting men with an underlying genetic susceptibility. Objective: To explore differences in risk of early prostate cancer death among men with higher vs lower genetic risk to inform prevention efforts. Design, Setting, and Participants: This cohort study used a c
Objective: To identify and quantify potential risk factors for osteoarthritis (OA) following traumatic knee injury. Design: Systematic review and meta-analyses that estimated the odds of OA for individual risk factors assessed in more than four studies using random-effects models. Remaining risk factors underwent semiquantitative synthesis. The modified GRADE (Grading of Recommendations Assessment
Importance: Disulfiram has demonstrated broad antitumoral effect in several preclinical studies. One of the proposed indications is for the treatment of glioblastoma. Objective: To evaluate the efficacy and safety of disulfiram and copper as add-on to alkylating chemotherapy in patients with recurrent glioblastoma. Design, Setting, and Participants: This was a multicenter, open-label, randomized p
BACKGROUND: The administration of endocrine therapy for 5 years substantially reduces recurrence rates during and after treatment in women with early-stage, estrogen-receptor (ER)-positive breast cancer. Extending such therapy beyond 5 years offers further protection but has additional side effects. Obtaining data on the absolute risk of subsequent distant recurrence if therapy stops at 5 years co
Importance: Hypochondriasis, also known as health anxiety disorder, is a prevalent, yet underdiagnosed psychiatric disorder characterized by persistent preoccupation about having serious and progressive physical disorders. The risk of mortality among individuals with hypochondriasis is unknown. Objective: To investigate all-cause and cause-specific mortality among a large cohort of individuals wit
Background: Blood-based biomarkers for Alzheimer's disease (AD) might facilitate identification of participants for clinical trials targeting amyloid beta (Abeta) accumulation, and aid in AD diagnostics. We examined the potential of plasma markers Abeta(1-42/1-40), glial fibrillary acidic protein (GFAP) and neurofilament light (NfL) to identify cerebral amyloidosis and/or disease severity. Methods
Background and aims: Children with extremely low-birth weight (ELBW) have a high risk for cognitive, motor, and attention impairments and learning disabilities. Longitudinal follow-up studies to a later age are needed in order to increase understanding of the changes in neurodevelopmental trajectories in targeting timely intervention. The aims of this study were to investigate cognitive and motor
The EU Battery Regulation (Regulation (EU) 2023/1542) mandates that by February 2027, electronic products must be designed so that users or independent professionals can replace their own batteries. While implementing this legislation in larger devices is relatively straightforward, it is unfortunately more difficult for small wearable electronics, such as in-ear headphones, due to their compact d
Background: Emerging evidence suggests that anterior cruciate ligament (ACL) ruptures can restore ACL fiber continuity. The relationship between ACL continuity on magnetic resonance imaging (MRI) (sign of ACL healing) and outcomes >5 years after an acute ACL rupture has not been investigated. Purpose: This study aimed to (1) describe clinical outcomes and radiographic osteoarthritis (ROA) at 11 ye
Increasing CO₂ emission is considered as the main reason for global warming in the world. One of the reasons for producing CO₂ is using of fossil-based materials in the construction projects. This study intends to assess the using bio-based materials instead of fossil-based materials for the thermal insulation layer of the external walls and roofs. Another focus of this project is using green conc
