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Public Procurement for Innovation (PPI) requires multiple roles from the public administration according to the problem-solution space, delineated by the level of consensus around the definition of the needs of the contracting authority and the potential solutions to address them. Each role involves a distinct mix of capabilities, which we categorize as ordinary (i.e. doing things right), dynamic

Sustainable Developments by Artificial Intelligence and Machine Learning for Renewable Energies analyzes the changes in this energy generation shift, including issues of grid stability with variability in renewable energy vs. traditional baseload energy generation. Providing solutions to current critical environmental, economic and social issues, this book comprises various complex nonlinear inter

The challenge of urbanisation, caused by an increase in city population, is increasing demand for imported food products. Food supplies may be impacted by the exponential increase in food demand caused by a constantly expanding global population. Growing and producing food in urban areas has now become a common practice. Addressing food system challenges through the adoption of urban farms on gree

The bone marrow (BM) niche is a complex cellular, molecular, and physical microenvironment capable of homing and supporting hematopoiesis. It is characterized by its ability both maintain and to drive hematopoietic stem and progenitor cells (HSPCs) self-renewal and differentiation which ultimately generate all blood cell types. However, how the niche elements interact in a human context remains la

Background: Dexmedetomidine is a selective alpha-2 agonist with minimal impact on the haemodynamic profile. It is thought to be safer than morphine or stronger opioids, which are drugs currently used for analgesia and sedation in newborn infants. Dexmedetomidine is increasingly being used in children and infants despite not being licenced for analgesia in this group. Objectives: To determine the o

In this Perspective, we discuss thermal imbalance and the associated electron-mediated thermal transport in quantum electronic devices at very low temperatures. We first present the theoretical approaches describing heat transport in nanoscale conductors at low temperatures, in which quantum confinement and interactions play an important role. We then discuss the experimental techniques for genera

The ribosome is an essential drug target as many classes of clinically important antibiotics bind and inhibit its functional centers. The catalytic peptidyl transferase center (PTC) is targeted by the broadest array of inhibitors belonging to several chemical classes. One of the most abundant and clinically prevalent mechanisms of resistance to PTC-acting drugs is C8-methylation of the universally

In this chapter, I problematise how “heroes” can be constructed in modern football clubs in spite of constant change and short stays. Narratives from the transfer system in Sweden are juxtaposed with media stories about players’ rationale for staying, transferring or choosing a certain club. The analysis suggests that the persistence of the hero-story and emotional connections are possible to forg

Buildings are responsible for 40% of energy consumption and 36% of CO2 emissions in the EU. Sweden andDenmark are cold climatic countries with strong demand for space heating and hot water in the residential sector. Large section of the detached houses in these countries are built more than 30 years ago and need refurbishment. Despite of huge energy saving potentials with deep renovation of these

Encapsulation in self-assembled lipid structures has been shown to increase the stability of large biomolecules, including proteins and nucleic acids (NAs), which has many potential applications in the food and pharmaceutical industries. In order to fully optimise the encapsulation system for a certain application, however, it is important to understand the effect of the encapsulated biomolecule o

With the two nations taking steps towards a more harmonized agenda on climate change mitigation, we would expect these leading plastic producer countries to also show leadership in relation to plastics.

Objectives: Global health challenges are complex and new approaches are pivotal. Engagement in arts and cultural activities is commonplace across different cultures, and research shows associations with benefits for health and wellbeing. Using the arts for health promotion and prevention of illness has increased worldwide. Study design: A population-based study. Methods: Data were obtained from th

BACKGROUND: Very preterm infants often require respiratory support and are therefore exposed to an increased risk of chronic lung disease and later neurodevelopmental disability. Although methylxanthines are widely used to prevent and treat apnea associated with prematurity and to facilitate extubation, there is uncertainty about the benefits and harms of different types of methylxanthines.OBJECTI

A distinctive representation of image patches in form of features is a key component of many computer vision and robotics tasks, such as image matching, image retrieval, and visual localization. State-of-the-art descriptors, from hand-crafted descriptors such as SIFT to learned ones such as HardNet, are usually high-dimensional; 128 dimensions or even more. The higher the dimensionality, the large

This chapter brings the Global South to the centre stage of degrowth debates to envision what a truly global and anti-colonial movement towards degrowth could look like. To do so, we first bring the varying definitions of the term ‘Global South’ to the forefront and consider the Global South not as an undynamic and apolitical cate- gory, but as a site of resistance and independent critical thinkin

This paper reports on efforts to create a robotized construction build system, based on the Finja Exakt manual build system. The equipment used is a generic off-the-shelf industrial arm robot integrated with a spindle crane carrier for mobility. The approach offers technical, safety and usability challenges as well as integration and business challenges for placing a generic industrial robot onsit

The problem of finding maximum (or minimum) witnesses of the Boolean product of two Boolean matrices (MW for short) has a number of important applications, in particular the all-pairs lowest common ancestor (LCA) problem in directed acyclic graphs (dags). The best known upper time-bound on the MW problem for n × n Boolean matrices of the form O(n2.575) has not been substantially improved since 200