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Abstract in Undetermined ABSTRACT. Optical techniques for tissue diagnostics currently are experiencing tremendous growth in biomedical applications, mainly due to their noninvasive, inexpensive, and real-time functionality. Here, we demonstrate a hand-held fiber optic probe instrument based on fluorescence/reflectance spectroscopy for precise tumor delineation. It is mainly aimed for brain tumor
In high-income countries, non-communicable diseases drive the demand for surgical healthcare. Middle-income countries face a double disease burden, of both communicable and non-communicable disease. The aim of this study was to describe the role of surgery for the in-hospital care of infectious conditions in the high-income country Sweden and the middle-income country South Africa.
In Safeguards work under the Non-Proliferation Treaty, the isotopic analysis of uranium and plutonium micro particles has strengthened the means for detecting undeclared nuclear activities. In order to assure accuracy and precision in the analytical methodologies used, the instrumental techniques need to be calibrated. The objective of this study was to produce and characterize particles consistin
The effects of the physical-spatial-technical environment on aging well have been overlooked both conceptually and empirically. In the spirit of M. Powell Lawton's seminal work on aging and environment, this article attempts to rectify this situation by suggesting a new model of how older people interact with their environment. Goals of the paper include (a) integration of the essential elements o
Cerebral small vessel disease (SVD) is a common accompaniment of ageing. Features seen on neuroimaging include recent small subcortical infarcts, lacunes, white matter hyperintensities, perivascular spaces, microbleeds, and brain atrophy. SVD can present as a stroke or cognitive decline, or can have few or no symptoms. SVD frequently coexists with neurodegenerative disease, and can exacerbate cogn
Understanding biodiversity patterns poses a persistent challenge due to the complex interconnections of ecological and evolutionary processes. The particular difficulty comes from the various processes influencing biodiversity patterns across different spatial scales. This thesis aims to enhance comprehension of community diversity patterns by employing theoretical models that are capable of gener
Online Raman scattering and in situ extinction measurement were combined in this work for qualitative and quantitative evaluations of various soot in the aerosol phase with different organic compounds.
Linking clinical multi-omics with mechanistic studies may improve the understanding of rare cancers. We leverage two precision oncology programs to investigate rhabdomyosarcoma with FUS/EWSR1-TFCP2 fusions, an orphan malignancy without effective therapies. All tumors exhibit outlier ALK expression, partly accompanied by intragenic deletions and aberrant splicing resulting in ALK variants that are
Low-and-middle-income countries (LMICs) bear a high burden of intimate partner violence (IPV). However, there are no reviews assimilating the factors affecting risk of IPV in LMICs. This systematic review (2010–20) identifies risk and protective factors of IPV in LMICs. We followed the PRISMA guidelines to review 399 studies and included 32 studies. Studies were of ever-partnered women living in a
The European Union (EU) Water Framework Directive is of paramount importance for water management. According to the legal text, coordination with other directives like the Floods Directive is imperative and motivated by potential synergy effects. In this paper, the degree to which such coordination is achieved is evaluated for five Nordic and Baltic countries. The evaluation is based on legal docu
In the coming renewables-based energy transition, global electricity consumption is expected to double by 2050, entailing widespread end-use electrification, with significant impacts on energy efficiency. We develop a long-run, worldwide societal exergy analysis focused on electricity. Our 1900–2017 electricity world database contains the energy carriers used in electricity production, final end-u
Depressive and anxiety disorders are leading causes of disability globally. Therapist-guided, Internet-delivered cognitive behaviour therapy (ICBT) is an established treatment for depression and anxiety, but a considerable proportion of treated patients do not achieve sufficient improvement. Predicting symptom changes based solely on clinical variables is challenging, and genetic data could offer
Purpose: Abdominal wall complications can be reduced by adhering to guidelines for midline laparotomy closure. However, implementation of guidelines can be challenging. To address this issue, a laparotomy closure device for swift and standardized abdominal closure was developed. The study evaluated the quality of the suture, safety, and speed of the device in a clinical setting. Methods: A prospec
För att främja ett aktivt och hälsosamt åldrande (AHA) är det avgörande att förstå hur olika generationer använder digitala teknologier, då dessa verktyg blir en alltmer integrerad del av vardagen. Detta avhandlingsprojekt undersökte teknikanvändning bland kvinnor och män i tre åldersgrupper som representerar olika generationer (30–39, 50–59 och 70–79 år), med fokus på attityder, användningsmönsteTo promote active and healthy ageing (AHA), it is essential to understand how different generations engage with digital technologies, as these tools are becoming increasingly integral to everyday life. This thesis project explored technology adoption among men and women from three age groups representing different generations (30–39, 50–59 and 70–79 years), focusing on attitudes, usage patterns, a
The metalorganic chemical vapor deposition (MOCVD) dynamics of beta-gallium oxide (β-Ga2O3) growth using trimethylgallium (TMGa) and oxygen as precursors were investigated through both theoretical thermodynamic analysis and experimental validation in a horizontal low-pressure hot-wall reactor. Thermodynamic analysis revealed that high-purity β-Ga2O3 can be grown through the complete combustion of
Gamified virtual reality (VR) environments are increasingly used to enhance engagement and learning, yet most designs still adopt a one-size-fits-all approach that overlooks motivational diversity. The HEXAD framework, which classifies users into six player types, provides a promising lens for addressing this gap, but its predictive validity in immersive VR remains contested. This study investigat
