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The value of bladder mapping and prostatic urethra biopsies for detection of carcinoma in situ (CIS).

Study Type - Diagnostic (case series) Level of Evidence 4 What's known on the subject? and What does the study add? It is well known that CIS is a major risk factor for muscle-invasive bladder cancer and that this entity can be difficult to diagnose. Taking cold-cup mapping biopsies from different areas of the bladder (BMAP) is commonly used in patients at risk of harbouring CIS. The diagnostic ac

Clinical probability assessment and biochemical markers in the diagnosis of deep vein thrombosis

Popular Abstract in Swedish Övergripande syfte Syftet med avhandlingen var att utvärdera hur en förenklad metod för diagnostisering av blodproppar i benets djupa ådror (djup ventrombos (DVT)) fungerar i svensk rutinsjukvård. Den förenklade metoden innebär användning av en strukturerad klinisk sannolikhetsbedömning tillsammans med ett blodprov (D-dimer test). Vi jämförde också vår D-dimermetod med The combination of pre-test clinical probability assessment and D-dimer test is now widely applied in the diagnostic process of DVT. The general objective of the present investigation was to validate these results in a Swedish routine emergency setting were the prevalence of the disease is high and were the clinical probability assessment was handled by many junior physicians. Furthermore, our aim

Återkallelse vid fusk och lögner - Om negativ rättskraft i migrationsrätt och allmän förvaltningsrätt

Ett gynnande svenskt förvaltningsbeslut får som huvudregel inte ändras. Detta brukar kallas att beslutet vinner negativ rättskraft, eller att det är orubbligt. Till denna huvudregel finns ett antal undantag. Ett av undantagen är om den enskilde vilselett myndigheten och därmed fått ett gynnande beslut som denne inte hade rätt till. Uppsatsen behandlar i vilka situationer svenska myndigheter får åIn Swedish administrative law a favourable decision is, as a general principle, immoveable (res judicata). There are a few exceptions to this general principle, one of which is when an induvial have mislead a government authority and as a result have been granted a favourable decision the individual was not entitled to. This essay deals with the question of in which situations Swedish authorities

Barnets bästa och uppehållstillstånd - Hur principen om barnets bästa påverkar möjligheten till uppehållstillstånd i Sverige; med fokus på hur principen utvecklats sedan barnkonventionens ikraftträdande

Denna uppsats syftar till att utreda hur principen om barnets bästa har utvecklats, med fokus på möjligheten att få uppehållstillstånd i Sverige, sedan barnkonventionen ratificerades av Sverige. FN:s barnkonvention antogs av FN:s generalförsamling 1989, och ratificerades av Sverige 1990. Av art. 3 i barnkonventionen framgår att ”[v]id alla åtgärder som rör barn, vare sig de vidtas av offentliga elThe aim of this study is to investigate how the principle of the best interests of the child has developed, with a focus on the possibility of obtaining a residence permit in Sweden, since the UN Convention on the Rights of the Child was ratified. The UN Convention on the Rights of the Child was adopted by the UN General Assembly in 1989 and ratified by Sweden in 1990. Art. 3 of the Convention on

Investigation of Gaia and GaiaNIR using selection functions on star clusters

Satelliten Gaia har samlat data för ESA sedan den skjöts upp år 2013. Denna data har gett astronomer en ny inblick i hur den galaktiska miljön ser ut i vår närhet. Gaia har varit ett så lyckat projekt att man nu har börjat arbeta med en uppföljare till Gaiasatteliten, GaiaNIR, som står för Gaia Near InfraRed. Planen är att GaiaNIR ska observera i det infraröda spektrumet, något som gör att extinktGaia Near InfraRed, or GaiaNIR for short, is a proposed successor to the original Gaia satellite. Its main improvement over the Gaia satellite is the fact that GaiaNIR will observe in the infrared spectrum. This would allow the telescope to see through the heavy extinction of the Milky Way, as the interstellar gas and dust obstructs light mainly in the visible spectrum. A selection function utiliz

Hints of a close outer companion to the ultra-hot Jupiter TOI-2109 b

Context. Hot Jupiters (HJs) with close-by planetary companions are rare, with only a handful of them having been discovered so far. This could be due to their suggested dynamical histories, which lead to the possible ejection of other planets. TOI-2109 b is special in this regard because it is the HJ with the closest relative separation from its host star, being separated by less than 2.3 stellar

Integrating data and analysis technologies within leading environmental research infrastructures : Challenges and approaches

When researchers analyze data, it typically requires significant effort in data preparation to make the data analysis ready. This often involves cleaning, pre-processing, harmonizing, or integrating data from one or multiple sources and placing them into a computational environment in a form suitable for analysis. Research infrastructures and their data repositories host data and make them availab

Immersion freezing ability of freshly emitted soot with various physico-chemical characteristics

The immersion freezing ability of soot particles has in previous studies been reported in the range of low/insignificant to very high. The aims of this study were to: (i) perform detailed physico-chemical characterisation of freshly produced soot particles with very different properties, (ii) investigate the immersion freezing ability of the same particles, and (iii) investigate the potential link

Association Between Bone Mineral Density and Autoantibodies in Patients With Rheumatoid Arthritis

Objective: Autoantibodies, such as anti–citrullinated protein antibodies (ACPAs), have been described as inducing bone loss in rheumatoid arthritis (RA), which can also be reflected by bone mineral density (BMD). We therefore examined the association between osteoporosis and autoantibodies in two independent RA cohorts. Methods: Dual x-ray absorptiometry (DXA) of the lumbar spine and left hip was

Development of Models, Methods, and Materiel for Deep Tissue Imaging using Light, Ultrasound, and Spectral-Hole Burning

The medical imaging technique called “ultrasound optical tomography” (UOT) entails light scattered in tissue that is given spatial information by interacting with an ultrasound field, thus allowing for molecular information to be imaged with ultrasonic resolution. This thesis discusses how UOT can be implemented, with most attention put toward the implementation using spectral-hole-burning filters

Global maps of soil temperature

Research in global change ecology relies heavily on global climatic grids derived from estimates of air temperature in open areas at around 2 m above the ground. These climatic grids do not reflect conditions below vegetation canopies and near the ground surface, where critical ecosystem functions occur and most terrestrial species reside. Here, we provide global maps of soil temperature and biocl

Fouling investigation of the bipolar membrane during electro-acidification of skim milk using X-ray micro-computed tomography

Introduction. Electrodialytic processes have become relevant technology in promoting sustainability within the food industry. Bipolar membrane electrodialysis (EDBM) offers an efficient and eco-friendly alternative for skim milk (SM) acidification, eliminating the need for added acids that affect milk properties and mineral composition [1-2]. In this study, the fouling behavior of bipolar membrane

Service continuity in Swedish grocery distribution under disruptions - Evaluating microbuffers across disruption scenarios

Sweden’s grocery distribution is routed through a limited number of upstream hubs and relies on corridors and ferry links. When disruptions affect a hub or a critical link, reallocations propagate fast and travel times increase, with some areas losing coverage temporarily. Decentralising the whole system is costly, so targeted resilience options must be evaluated. The purpose of this thesis is to

Clinical applications of HPV testing: A summary of meta-analyses

Background: More than ever, clinicians need regularly updated reviews given the continuously increasing amount of new information regarding innovative cervical cancer prevention methods. Material and methods: A summary is given from recently published meta-analyses on three possible clinical applications of human papillomavirus (HPV)-DNA testing: triage of women with equivocal or low-grade cytolog

Nuclear Magnetic Resonance for Diffusion Imaging Development and evaluation of spin-echo-based pulse sequences for in vivo studies of water self-diffusion

The interest in diffusion imaging with nuclear magnetic resonance techniques has increased during the last few years. The main reason is the possibility of early diagnosis of acute ischaemic stroke, at a time when conventional MR techniques and computerised tomography fail. The purpose of this study was to develop and evaluate methods for the measurement of water self-diffusion in vivo usin

Biomassebaserade energibärare för transportsektorn

Det finns en stor potential för ett ökat utnyttjande av biomassa för energiändamål i Sverige. En ökad användning av biomassa skulle kunna bidra till att minska utsläppen av koldioxid från förbränning av fossila bränslen, minska beroendet av importerade fossila energibärare samt påverka den regionala och lokala miljösituationen såväl positivt som negativt. Föreliggande studie behandlar framför alltThere is a large potential for increasing the use of biomass for energy purposes in Sweden. Increasing the use of biomass can reduce emissions of carbon dioxide (CO2) from fossil-fuel combustion and dependence on imported fossil fuels. Furthermore, increased biomass use will affect emissions of other air pollutants than carbon dioxide as well as environmental impacts from land use. The study deals

Ett leading mätsystem för leveranstillförlitlighet från en monteringsprocess

Issue of Study: The case company, Metius, has difficulties in meeting its customers’ demands for delivery reliability due to issues in the final assembly process. A leading management control system linked to the company’s final assembly could allow the production management to act proactively and avoid more dissatisfied customers due to poor delivery reliability. Relevant literature gives little

Two-photon fluorescence lifetime imaging applied to the mixing of two non-isothermal sprays : temperature and mixing fraction measurements

Droplets temperature is a key parameter for the study of heat and mass transfers in many spray applications. Time correlated single photons counting (TCSPC) is applied to monitor the fluorescence decay and determine the droplet temperature in the mixing zone of two sprays which are injected with significantly different temperatures. For some well-chosen fluorescent dye, like rhodamine B (RhB), the

Differences between mono-generic and mixed diatom silicon isotope compositions trace present and past nutrient utilisation off Peru

In this study we combine for the first time silicon (Si) isotope compositions of small mixed diatom species (δ30SibSiO2) and of large handpicked mono-generic (i.e. genus=Coscinodiscus) diatom samples (δ30SiCoscino) with diatom assemblages extracted from marine sediments in the Peruvian upwelling region in order to constrain present and past silicate utilisation. The extension of a previous core-to

Different antibiotic treatments for group A streptococcal pharyngitis

Background: Antibiotics provide only modest benefit in treating sore throat, although their effectiveness increases in people with positive throat swabs for group A beta-haemolytic streptococci (GABHS). It is unclear which antibiotic is the best choice if antibiotics are indicated. This is an update of a review first published in 2010, and updated in 2013, 2016, and 2021. Objectives: To assess the