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AIMS: To investigate the disease causing event in patients with familial hypercholesterolaemia, carrying two mutations each, E256K in exon 6 and I402T in exon 9, of the gene encoding the low density lipoprotein (LDL) receptor. It was not known whether the mutations were positioned in cis or trans, or if they were each pathogenic separately or only when present together. METHODS: Polymerase chain r
The thesis deals with ritual remembrance ceremonies enacted in the three towns of Mostar, Jajce and Višegrad in BiH. The Old Bridge in Mostar, the Bridge over the Drina in Višegrad and the AVNOJ Museum in Jajce all carry a material presence that influences everyday life in these localities. Through ethnographic fieldwork, insights into local practices in relation to those World Heritage Sites are
Replacing fossil fuels by biofuels and increasing energy efficiency are often considered to be options for reducing the net emission of greenhouse gases. This thesis presents the results of analyses of energy efficiency, emission and cost of whole energy system chains, from the natural resource to the end user when heating detached houses in a Swedish context. External costs and taxes of the energ
Background: Accurate prehospital trauma triage is crucial for identifying critically injured patients and determining the level of care. In the prehospital setting, time and data are often scarce, limiting the complexity of triage models. The aim of this study was to assess whether, compared with logistic regression, the advanced machine learner XGBoost (eXtreme Gradient Boosting) is associated wi
Monte Carlo (MC) modelling techniques have been used extensively in Nuclear Medicine (NM). The theoretical energy resolution relationship (∝1/E−−√), does not accurately predict the gamma camera detector response across all energies. This study aimed to validate the accuracy of an energy resolution model for the SIMIND MC simulation code emulating the Siemens Symbia T16 dual-head gamma camera.Me
Determining the architecture of multi-planetary systems is one of the cornerstones of understanding planet formation and evolution. Resonant systems are especially important as the fragility of their orbital configuration ensures that no significant scattering or collisional event has taken place since the earliest formation phase when the parent protoplanetary disc was still present. In this cont
The aim of the study was to examine the role culture plays in caregiver’s pain-related parent behaviors. This study used a cross-cultural survey design with a convenience sample of caregivers of 6-12-year-old children (N = 547) living in Canada (n = 183), Iceland (n = 184), or Thailand (n = 180). A team-translation approach included psychometric assessment and confirmatory factor analysis, ensurin
Increasing aridity is one major consequence of ongoing global climate change and is expected to cause widespread changes in key ecosystem attributes, functions, and dynamics. This is especially the case in naturally vulnerable ecosystems, such as drylands. While we have an overall understanding of past aridity trends, the linkage between temporal dynamics in aridity and dryland ecosystem responses
Background: Welders are exposed to gas and particle emissions that can cause severe lung disease, such as chronic obstructive pulmonary disease (COPD), a leading cause of mortality and morbidity worldwide. It is difficult to detect COPD early and therefore mitigating measures may be delayed. The aim of this study was to investigate lung health in welders and evaluate new sensitive methods with pot
The aim of this thesis was to explore the perceptions of, prerequisites for and benefits of user involvement among older people, persons with functional impairments and other user groups important to the research area. By using an adapted conceptual tool to categorize the various user involvement studies comprising the thesis, the aim wasalso to reflect on the importance of study design for the ou
When a swift heavy ion (SHI) penetrates amorphous SiO2, a core/shell (C/S) ion track is formed, which consists of a lower-density core and a higher-density shell. According to the conventional inelastic thermal spike (iTS) model represented by a pair of coupled heat equations, the C/S tracks are believed to form via "vaporization" and melting of the SiO2 induced by SHI (V-M model). However, the mo
Objective: Previous work suggested that the ultrasound-based benign Simple Descriptors can reliably exclude malignancy in a large proportion of women presenting with an adnexal mass. We aim to validate a modified version of the Benign Simple Descriptors (BD), and we introduce a two-step strategy to estimate the risk of malignancy: if the BDs do not apply, the ADNEX model is used to estimate the ri
This thesis work has focused on the platinum-tin surface, especially how it behaves when exposed to gases like oxygen and carbon monoxide. Platinum-tin is used as a catalyst for a range of reactions, including the oxidation of carbon monoxide at mild conditions, which is important for gas purification in fuel cells. The platinum-tin alloy has properties useful for the reactions it catalyses, but i
Background: People with HIV (PWH) have a high burden of coronary plaques; however, the comparison to people without known HIV (PwoH) needs clarification. Objectives: The purpose of this study was to determine coronary plaque burden/phenotype in PWH vs PwoH. Methods: Nonstatin using participants from 3 contemporary populations without known coronary plaques with coronary CT were compared: the REPRI
Abstract: Title: Intelligent housing. Author: Tobias Nilsson, Student at Lund University. Director: Petter Wallentén, Senior Lecturer at the Department of Building Physics, Lund University. Examiner: Mats Dahlblom, Lecturer at the Department of installation and climate con-trol, Lund University. Problem identification: • What techniques and systems are making homes intelligent? • What opportunitie
Mixed Martial Arts (MMA) är en idrott som fått ökad popularitet de senaste åren, inte minst i Sverige. Idrotten är våldsam och tillåter olika typer av våld mot huvudet vilket utgör en fara för utövarnas liv och hälsa. För att säkra utövarnas säkerhet krävs det att utövningen sker under kontrollerade former. Men var går egentligen gränsen för vad som är tillåtet ur ett straffrättsligt perspektiv? Mixed Martial Arts (MMA) is a sport that has seen an increase in popularity in the last couple of years, including Sweden. The sport is violent and allows for several forms of violence against once head which can risk the lives and health of the practitioners. To secure the safety of practitioners it is required that the practice is performed under controlled forms. But how do you draw the line of
Denna uppsats behandlar regleringen rörande hyper- och inlinelänkar till upphovsrättsskyddat material på internet. Uppsatsen analyserar även potentiella samhällsekonomiska konsekvenser av regleringen ur ett rättsekonomiskt perspektiv. Länkar fungerar som ett verktyg för att underlätta navigering på internet. Upphovsrätten skyddar den som skapat ett litterärt eller konstnärligt verk. I Sverige reglThis essay deals with the regulation regarding inline- and hyperlinks to copyright protected material on the Internet. The essay also analyses the potential consequences of the regulation with an economic analysis of law. Links serve as a tool to navigate on the Internet. Copyright protects the author of a literary or artistic work. In Sweden this right is governed by URL. This law has been adapte
Written essay investigates Gothenburg municipalitys´ new policy which tries to integrate unaccompanied minors in strong socio-economic neighborhoods. This essay therefore tries to answer the question of how prepared these communities are for integrating their new neighbors,- this is done by a case study of city district of Örgryte-Härlanda, which is one of many places planned for temporary accommo
Den här uppsatsen behandlar principen om barnets bästa och rätten att komma till tals i FN:s konvention om barnets rättigheter (barnkonventionen) och föräldrabalken. Enligt 6 kap. 2 a § FB ska barnets bästa alltid komma i främsta rummet när frågor om vårdnad, boende och umgänge avgörs. I tredje stycket stadgas att vid bedömningen av barnets bästa ska hänsyn tas till barnets vilja med beaktande av This essay talks about the concept of the child’s best interests and the right of the child to be heard in the United Nations Convention on the Rights of the child and the Children Parents Code. According to the 6th chapter, section 2(a) in the Children Parents Code, the best interest of the child shall constitute the primary consideration in the determination of all questions concerning custody,
