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There are excellent guidelines for clinicians to manage venous diseases but few reviews to assess their hemodynamic background. Hemodynamic concepts that evolved in the past have largely remained unchallenged in recent decades, perhaps due to their often complicated nature and in part due to emergence of new diagnostic techniques. Duplex ultrasound scanning and other imaging techniques which evolv

Context. The third Gaia data release provides photometric time series covering 34 months for about 10 million stars. For many of those stars, a characterisation in Fourier space and their variability classification are also provided. This paper focuses on intermediate- to high-mass (IHM) main sequence pulsators (M'a ¥''1.3'M') of spectral types O, B, A, or F, known as β Cep, slowly pulsating B (SP

In the domain of current spatial semiotics two important, but also radically different, approaches can be distinguished as modelling the co-operative agency of human, material and legal properties of space, namely that of Manar Hammad’s and that of Bruno Latour’s. Hammad, being a semiotician, more true to the Greimasian heritage, regards a finite set of principal actantial types (owners, visitors,

Sweden’s investment level has recently been the subject of keen debate. One fact that is often brought up is the fall in Swedish investment as a proportion of GDP (investment ratio) and that the current level of Swedish investment is below that of other countries. In the long run, low investment can weaken a country’s potential for growth. Although Swedish investment is comparatively low, Sweden i

The nature of today’s business demands that Business Analytics (BA) extends to an operational level to better support employees in their decision-making. This is noticeable from the constant requests for new reports and changes in old ones at different employee levels. As a result, BA specialists or other power-users in functional departments are “bombarded” by these requests, and it becomes more

In January 1990 an expert group was set up by DP2 of TC2, CEC to define the research and development work needed to be undertaken within the community to achieve a robust solution with respect to reaction-to-fire material classification. The expert group delivered in December 1990 its proposal for a 5-year research and development program. But a system of harmonised European fire test methods and

Type 2 diabetes is a serious, lifestyle-related condition characterized by insufficient glycemic control resulting in hyperglycemia. Long-term hyperglycemia is a major risk factor for a range of health complications, and type 2 diabetes complications are among the leading causes of morbidity and mortality worldwide. Of all forms of diabetes, type 2 diabetes constitutes around 90% of cases, indicat

Recent advancements in catchment hydrology (such as understanding hydrological processes, accessing new data sources, and refining methods for parameter constraints) make it possible to apply catchment models for ungauged basins over large domains. Here we present a cutting-edge case study applying catchment-modelling techniques at the global scale for the first time. The modelling procedure was c

To remain competitive in the field of manufacturing today, companies must make their industrial robots smarter and allow them to collaborate with one another in a more effective manner. This is typically done by adding some form of learning, or artificial intelligence (AI), to the robots. These learning algorithms are often packaged as cloud functions in a remote computational center since the amo

Maria Nyman The Borders of travelling. Russia in Swedish travel accounts during the 18th century. The primary objective of this study concerns how culturally created images of the Same and the Other, is expressed in descriptions of a journey, a sojourn someplace else. More specifically, the dissertation investigates how a number of Swedes, travelling during the eighteenth- and early nineteenth cen

Popular Abstract in Danish Genterapi er en attraktiv terapiform mod neurologiske lidelser som Parkinsons sygdom og epilepsi af flere grunde. Gener med en terapeutisk effekt kan introduceres lokalt ved præcise injektioner i det syge væv, hvor genproduktet kan frigives fra nerveceller i respons til aktivitet i det omgivende væv. Ved genterapi omgås den forhindring som blod-hjernebarrieren udgør, ligGene therapy is an attractive strategy for neurological disorders, such as Parkinson’s disease and epilepsy, for several reasons. Introduction of genes with a therapeutic potential can be achieved locally, by accurate injections in the compromised tissue, and release of a transgene therapeutic substance can be regulated by the surrounding host neural circuitry. The gene therapy approach circumvent

This thesis consists of four theoretical essays on contingent claim analysis and its connection to Malliavin calculus. The first three papers are analyzed in the famous Black and Scholes model, while the setup of the fourth paper involves an international environment and the presence of exchange rates. In the first essay the tractability of the Malliavin calculus approach to derive the replicatin

X-linked retinoschisis (XLRS) is a congenital progressive inherited retinal disease that affects the entire retina and is one of the more common causes of vision loss from retinal degeneration affecting young men,. The progression is variable but seems to be relatively stationary in the ages 6 to 25 years. Patients with XLRS lack a functional retinoschisin protein in the eye, because of mutation i

Pulsatile flows in geometries of physiological relevance have been investigated. Atherosclerotic plaques are (initiated) near junctions and bifurcations in larger arteries. The flow in these regions is characterized by flow separation and unsteadiness, which indicates that local flow conditions contribute to atherogenesis. Flows in curved and bifurcating pipes have been investigated over many y

Popular Abstract in Swedish Akut mellanöreinflammation (akut otitis media, AOM) är en av barnaålderns vanligaste sjukdomare och en av dem som oftast föranleder antibiotikabehandling. De flesta barn får bara någon enstaka AOM, men cirka 5% av dem som insjuknar drabbas sedan av upprepade infektioner (s.k. otit-benägna barn) och blir till ett problem både för patienten, dennes familj och samhället. DAcute otitis media (AOM) is one of the most common childhood diseases and the most common causes of antibiotic treatment in small children. Most children will experience one or two episodes of AOM during preschool age but some will suffer from repeated attacks, they will become otitis-prone. Complications with severe, sometimes fatal infections such as acute mastoiditis and meningitis are nowadays

Over the last few decades, increasing rates of change in the structure and function of ecosystems have been brought about by human modification of land cover, of which a major component is vegetation. Metrics derived from linear regression models applied to high temporal resolution satellite data are commonly used to estimate rates of vegetation change. This approach implicitly assumes that vegeta

Popular Abstract in Chinese 北极和亚北极地区对全球气候变化影响尤为重要。目前，北极地区正面临着变暖速度高于全球平均的现状。全球大约有50%的土壤碳储存在高纬度地区的土壤里，这些土壤碳主要分布于冻土层和泥炭层中。冻土层的解冻会使原先被冻结的土壤碳加速分解，产生温室气体，从而对全球变暖形成一个强烈的正反馈。与此同时，气温的增加可能会很大程度地影响植被在这些地区的生长和分布。动态生态系统模型是一种非常强大的工具，被用来研究气候变化对生态系统的影响，并且可以量化生态系统对大气的反馈信息。然而这些模型通常只关注大气、地表植被和土壤之间的水和碳的纵向转移，从而忽略了其在模型空间单元中的横向移动。这样可能会导致模型对于水和碳平衡的计算不够准确和全面，尤其在气候敏感的高纬度极地地区，这种偏差可能会更大。 本论文旨在解决动态生态系统模型中的这个局限性问题。基于目前最先进的动态生态The Arctic and Subarctic regions are of particular importance to the global climate change and are now experiencing a climate warming that is higher than the global average. Around 50% of the global soil carbon is stored in high latitude soils, especially in permafrost and peatland soils. Permafrost thawing, speeding up the decomposition of previously frozen soil carbon, is expected to result in s

Popular Abstract in Swedish Ett varmare klimat ökar generellt risken för angrepp av skadeinsekter på jordbruksgrödor, och många skadeinsekter förväntas sprida sig norrut. Den här avhandlingen fokuserar på hur ett varmare klimat kan påverka koloradoskalbaggen, en allvarlig skadegörare i potatisodlingar. Koloradoskalbaggen kom från Mexiko till Europa i början av 1900-talet, och har sedan dess spridiEuropean agriculture is facing the challenge of managing the impact of climate change on food security. Agriculture in a northern temperate climate is likely to benefit from higher temperature and longer growing season while, in the south, crop productivity is likely to decline. Such changes in climate could also affect the population dynamics of insect pests. The Colorado potato beetle (CPB) is o

The Complement system is a main effector mechanism of the innate immune system, acting to enhance clearance of pathogens, but also aids removal of biological debris from the body, including immunocomplexes, apoptotic/necrotic cells and protein aggregates. Complement regulators serve to prevent excessive inflammation and their interaction with the same materials targeted by the complement system re

LUDC-IRC Postdoctoral Program 2020 – Project 11 LUDC-IRC Postdoctoral Program 2020 – Project 11 Incretin biology in T2D -Still a black box PI: Nils Wierup Co-PI: Marju Orho-Melander Purpose and aims Type 2 diabetes (T2D) is a major global health problem and there is a need for improved therapies. Here we will use unique approaches to identify T2D disease mechanisms by studies in the small intestin

https://www.ludc.lu.se/sites/ludc.lu.se/files/wierup_project_11.pdf - 2026-05-03