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The polycations spermine, neomycin and polylysine potentiated Ca(2+)-activated force in beta-escin permeabilized guinea-pig ileum strips. The effect was inhibited by the calmodulin antagonists trifluoperazine, mastoparan and W13. Potentiation was slow or absent in chi-toxin permeabilized strips, indicating dependence on penetration of the polycations into cells. The effects of spermine and neomyci
Cooperative content replication and request routing (C2R3) has emerged as a promising technique to enhance the efficiency of content delivery networks (CDN). Most existing approaches to C2R3 focus on efficient bandwidth usage and assume a hierarchical CDN architecture targeted towards the delivery of specific content types (e.g., video). Therefore, C2R3 problem of covering the broad range of conte
Popular Abstract in Swedish Depression är ett allvarligt och potentiellt förödande hälsoproblem som drabbar flera miljontals människor i världen. Trots framsteg inom depressionsforskningen återstår flera frågor kring varför vissa individer upplever depression, och andra inte, och varför vissa blir hjälpta av behandling, och andra inte. Den forskning som rapporteras här tar som utgångspunkt hypotes
Popular Abstract in Swedish En fråga om liv och hälsa Livstillfredsställelse, personlighet och mortalitet i två äldre populationer Enligt en rapport från FN (2001) kan vi under de kommande 50 åren förvänta oss att andelen äldre över 60 år kommer att fördubblas. Ny och förbättrad teknik, medicinsk kunskap och behandling har utvecklats, vilket innebär att vi i dag överlever i större utsträckning dThe aims of the present thesis were to explore and describe elderly people’s morbidity and experience of symptoms in relation to life satisfaction, personality and mortality. (I, II and III) To learn from the individuals who have high life satisfaction in spite of the fact that they have concurrent medical diagnoses and conditions. (I and III) To reason how positive factors and strengths might hel
By the autumn of 1966, the PRC government had enjoyed seventeen years of uninterrupted and complete domestic information dominance. Independent collection of information was hampered by way of a CCP culture of secrecy and successfully enforced regimen of information curtailment. Of the changes in the political landscape triggered by Mao Zedong’s August 1966 decision to label part of government off
Popular Abstract in Swedish Förhållandet mellan utrikespolitik och demokrati har behandlats inom statsvetenskapen i hundratals år. En vanlig uppfattning har varit att behandlingen av utrikespolitiska frågor svårligen kan ske i demokratiska former. Inom utrikespolitiken har riksdagen traditionellt en svagare ställning gentemot regeringen än i inrikespolitiska frågor. I fokus för denna avhandling sThe increasing internationalization puts new demands on national democracy and national parliamentarism. The questions posed in this dissertation are if the parliamentary model for domestic policy or the parliamentary model for foreign policy is the most relevant when describing the role of the Swedish Riksdag (parliament) in European Union (EU) matters, and whether there have been any changes dur
The dissertation seeks to problematize the public debate which in recent years has made many people interested in and committed to the region. The empirical basis of the study is some of the regions of southern Sweden which have served as an important platform in the last thirty or forty years when the political and economic establishment has acted and argued in various contexts. The fundamental q
E-business is becoming more and more common today. The predictions of future growth give clear indications that companies will use e-business more and more. However in the growth of e-business it has been identified that there is a common lack of understanding in customer needs and logistics. In order to reduce some of this non-understanding this thesis seeks answers to the following question: - H
Popular Abstract in Swedish Bland kommunalskattelagens (KL) allmänna bestämmelser finns vissa regler som motverkar överföringar av obeskattade vinstmedel mellan företag. Om ett företag säljer en tillgång eller tjänst för ett pris understigande marknadsvärdet kan uttagsbeskattning ske. Om ett företag i stället köper en tillgång eller tjänst för ett pris överstigande marknadsvärdet är det möjligt atThis dissertation deals with the conflict of rules for the taxation of income. By 'conflict of rules' I refer to the circumstance that two or more provisions are applicable simultaneously, but where it is clear that only one of the provisions concerned could or should be applied. The dissertation concentrates on the relationship between the different provisions - within the Swedish legal system -
Popular Abstract in Swedish Något tillspetsat förefaller varje kommun driva utvecklingsarbete inriktat på verksamhetsmått. Är så inte fallet är ansvariga snabba att betona att verksamhetsmått är viktigt och att de precis har beslutat om ett större måttprojekt. Denna bok ger en bild av i vilken omfattning fyra gatukontor utformar och använder verksamhetsmått. Boken innehåller också beskrivningar ocThe purpose of this study is to develop a frame of reference within which formal control system performance measures can be described and their design and use can be analyzed for control systems in municipalities. From a cybernetic control approach measures are used as instruments to plan and gain feedback from employee actions, and adjust them to the internal and external environment of which the
Popular Abstract in Swedish Syftet med studien har varit att, genom huvudsakligen kvalitativ beskrivning, studera narrativ sekvens, d v s berättelsen, i exolingvala samtal mellan infödd och icke infödd (svensktalande studenter) talare av franska. Den teoretiska ramen sträcker sig från textlingvistik (Revaz, Adam, Bronckart etc.) till konversationsanalys (Labov, Sacks, Norrick, Laforest, Kerbrat-OrThe aim of this study is to examine, through a mainly qualitative description, the narrative in exolingual conversations in French between non-native speakers (NNS) (Swedish students) and native speakers (NS). The theoretical frame ranges from text linguistics (Revaz, Adam, Bronckart etc.) to conversation analysis (Labov, Sacks, Norrick, Laforest, Kerbrat-Orecchioni, Bres, Norrby etc.). The study
BACKGROUND: To determine if the common Pro12Ala polymorphism (rs1801282) of the peroxisome proliferator-activated receptor (PPARG) gene is associated with the metabolic syndrome (MetS) or with its individual components in middle-aged Swedish individuals. METHODS: MetS was defined according to the National Cholesterol Education Program/Adult Panel III (NCEP/ATP III), the International Diabetes Fede
Although the visual flight control strategies of flying insects have evolved to cope with the complexity of the natural world, studies investigating this behaviour have typically been performed indoors using simplified two-dimensional artificial visual stimuli. How well do the results from these studies reflect the natural behaviour of flying insects considering the radical differences in contrast
The aim of this paper is to develop and illustrate an analytic approach that brings the active making and makings of green consumer images to the fore. Efforts to “know” the green consumers have generated multiple representations. Enactments of the green consumer are not innocent but also play a role in shaping how we understand and approach sustainable consumption. Because of this it is important
The pedestrian safety problem is huge in all developing countries. The main aims of the project are therefore: 1/To understand pedestrian safety problem in a developing country, 2/To identify feasible traffic calming measures. International experiences were complemented by field studies at seven sites in the city of Jaipur. A wide range of field studies were made, out of which traffic conflict stu
Background: Positive intersexual genetic correlations are typically viewed as constraining the evolution of sexual dimorphism, when traits are subject to sexually antagonistic selection. Our study species, the damselfly Ischnura elegans, has a female-limited colour polymorphism with three female colour morphs (males are monomorphic), one of which is considered to be a male mimic. Questions: Are th
In mammals, including humans, the most consistent cognitive sex difference appears to be a male advantage in spatial ability. Usually, some sex-correlated selective advantage is inferred to explain this, for example, the need for males to navigate over large territories. In birds, sex differences in learning abilities are rare. Here, we show that females of a common European songbird, the great ti
The Swedish Family-Cancer Database comprises a total of 11.8 million individuals covering the Swedish population of the past 100 years. Version VIII of the Database is described in the present article. Cancer cases were retrieved from the Swedish Cancer Registry for the period 1958-2006, including more than 1 million first primary cancers. The number of familial cancers in offspring is 14,000 when
Recent developments in the application of x-ray micro-tomography in laboratory geomechanics have allowed all the individual grains of sand in a test sample to be seen and identified uniquely in 3D. Combining such imaging capabilities with experiments carried out ‘‘in situ’’ within an imaging set-up has led to the possibility of directly observing the mechanisms of deformation as they happen. The c
The plant respiratory chain contains several pathways which bypass the energy-conserving electron transport complexes I, III, and IV. These energy-bypasses, including type II NAD(P)H dehydrogenases and the alternative oxidase (AOX), may have a role in redox-stabilisation and regulation, but current evidence is inconclusive. Using RNA interference, we generated Arabidopsis thaliana plants simultane
