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Inflammation and Stem Cell Therapy for Stroke

Ischemic stroke is a leading cause of death and disability worldwide. Currently, there is no treatment that can promote recovery in the chronic phase. It has been shown that neurogenesis occurs in ischemic striatum in rodents and probably also in humans. Moreover, blood-borne macrophages have been found to enhance spontaneous post- stroke recovery in mice. These findings have suggested potential n

Between Nature and Modernity : Agroecology as an alternative development pathway: the case of Uganda

Jordbruksmodernisering har dramatiskt ökat tillgången till mat på global nivå, men till ett högt pris för miljön. Idag efterlyser många ett ’paradigmskifte’ i jordbruket, även flera stora mainstream-institutioner. Med ett skifte till vad? Under senare år har det synts en ökande tilltro till agroekologi, ett alternativ som syftar till att förstå och bedriva jordbruk som komplexa agroekosystem. FrånAgricultural modernization has massively increased global food supply, but at a high environmental cost. Today many are calling for an agricultural ‘paradigm shift’, including several mainstream institutions. But to what? In recent years, agroecology has gained credence as an alternative approach that seeks to understand and manage farms as complex agroecosystems. From a development perspective, i

Novel Retaining Glycoside Hydrolases : Potential candidates for transglycosylation and hydrolysis

Our society is moving towards renewable resources, where biomass, rich incarbohydrates, is producing chemicals and fuel. However, there are severallimitations when it comes to valorisation of the carbohydrates from renewablebiomass. One major hurdle is the over-functional nature of carbohydrates, making them difficult to process by conventional chemistry. Carbohydrate activeenzymes can help overco

Management of Acute Mesenteric Venous Thrombosis : A Systematic Review of Contemporary Studies

BACKGROUND AND AIMS: Acute mesenteric venous thrombosis accounts for up to 20% of all patients with acute mesenteric ischemia in high-income countries. Acute mesenteric venous thrombosis is nowadays relatively more often diagnosed with intravenous contrast-enhanced computed tomography in the portal phase than at explorative laparotomy No high-quality comparative studies between anticoagulation alo

Chronological age assessment in young individuals using bone age assessment staging and nonradiological aspects : Machine learning multifactorial approach

Background: Bone age assessment (BAA) is used in numerous pediatric clinical settings as well as in legal settings when entities need an estimate of chronological age (CA) when valid documents are lacking. The latter case presents itself as critical as the law is harsher for adults and granted rights along with imputability changes drastically if the individual is a minor. Traditional BAA methods

Pathogenesis of type 2 diabetes -role of defects in insulin secretion and insulin sensitivity

Popular Abstract in Swedish Bakgrund: Diabetes är en sjukdom som karakteriseras av kroniskt förhöjt blodsocker och som obehandlad kan leda till svåra komplikationer i blodkärl, ögon, njurar, nerver m.m. Sjukdomen beror på kroppens oförmåga att producera (typ 1 diabetes) eller svara på effekt av (typ 2 diabetes) hormonet insulin. Det finns ca 150 miljoner personer med diabetes i världen idag, och sType 2 diabetes is characterised by defects in insulin sensitivity, insulin secretion and increased endogenous glucose production. The relative contribution of each of these defects remains controversial. In order to characterise the metabolic defects in various stages of glucose tolerance, the insulin sensitivity and insulin secretion was measured in a large population based study in Finland and

Clinical Aspects of Hereditary Breast Cancer

Popular Abstract in Swedish Kliniska aspekter på ärftlig bröstcancer, en populärvetenskaplig sammanfattning på svenska Bröstcancer är den vanligaste cancerformen hos kvinnor. Ungefär 10% av kvinnorna i den svenska befolkningen får någon gång under livet denna sjukdom. Förekomst av sjukdomen i familjen är en av de starkaste riskfaktorerna för att en kvinna ska utveckla bröstcancer, och i 5-10% av A positive family history of breast cancer (BC) is one of the strongest predictors of the disease. Two major BC susceptibility genes, BRCA1 and BRCA2 were identified about a decade ago. In this thesis, studies of different biological. clinical and epidemiological aspects of hereditary BC are presented. In the first paper data on the expression of steroid hormone receptors in hereditary BC are pres

Making Pairs

This thesis makes a contribution to matching theory. It consists of five self-contained papers. It is a study predominately on the existence of stable outcomes. These are desirable both from a practical and a theoretical standpoint. Matching theory has grown in importance in recent years following its successful applications to, for instance, kidney exchange, the National Resident Matching Program

Low Power Decoding Circuits for Ultra Portable Devices

A wide spread of existing and emerging battery driven wireless devices do not necessarily demand high data rates. Rather, ultra low power, portability and low cost are the most desired characteristics. Examples of such applications are wireless sensor networks (WSN), body area networks (BAN), and a variety of medical implants and health-care aids. Being small, cheap and low power for the individua

The human diving response - effects of temperature and training

The aim was to elucidate the cardiovascular response associated with breath-hold diving, especially the effects of temperature in its elicitation and the effects of different types of training on the human diving response (DR) and breath-holding time (BHT), and to evaluate the human DR in a mammalian perspective. A model for simulated diving by apnea and facial immersion in cold water was develope

Numerical and Experimental Studies on the Effects of Flow on Drop Formation in Cross-flow Membrane Emulsification

Membrane emulsification is a gentle process that produces emulsions with a narrow drop size distribution, which increases the stability of the emulsion. The dispersed phase is forced through the pores in a membrane and drops are formed at the other side of the membrane where a continuous phase, flowing along the membrane surface, sweeps away the forming drops. The growth and detachment of drops is

A mathematical model of the Calvin photosynthesis cycle

A mathematical model is presented for photosynthetic carbohydrate formation in C3 plants under conditions of light and carbon dioxide saturation. The model considers reactions of the Calvin cycle with triose phosphate export and starch production as main output processes, and treats concentrations of NADPH, NAD+, CO2, and H+ as fixed parameters of the system. Using equilibrium approximations for a

Hydrolysis of microcrystalline cellulose by cellobiohydrolase I and endoglucanase II from Trichoderma reesei: Adsorption, sugar production pattern, and synergism of the enzymes

Microcrystalline cellulose (10 g/L Avicel) was hydrolysed by two major cellulases, cellobiohydrolase I (CBH I) and endoglucanase II (EG II), of Trichoderma reesei. Two types of experiments were performed, and in both cases the enzymes were added alone and together, in equimolar mixtures. In time course studies the reaction time was varied between 3 min and 48 h at constant temperature (40degreesC)

Capacitive power transfer to car through wheel - is it possible?

Introduction: This work aims to evaluate the possibility to transfer electrical power from a metal plate to the steel-cord within a car tire. If the tire stands on the plate, a connecting surface occurs which can be interpreted as a capacitor, where the rubber compound acts as a dielectric. Method: First the impedance of the tire is evaluated: An analytical model is set-up to describe the system;

The European Convention on Human Rights in Sweden: Legal Practice and Legal Theory Analysed

The European Convention on Human Rights (ECHR) has been part of Swedish domestic law since 1995 and the Swedish government and the Supreme Courts of Sweden asserts that Swedish courts implemented it. However, the European Court of Human Rights (ECtHR) have judged Sweden 61 times for violating the ECHR, including eight judgments regarding Article 3 (prohibition of torture). Thus, Swedish courts cle

Health-Related Quality of Life and Adherence in Haemophilia

Assessment of health-related quality of life (HRQoL) in haemophilia is important in order to provide information for clinical decision making and to verify the impact of haemophilia on patients and their families. Advances in haemophilia care and prophylactic treatment have improved HRQoL for the patients and where treatment is available, patients with haemophilia have almost reached the same life

Relating interannual variability of atmospheric CH4 growth rate to large-scale CH4 emissions from northern wetlands

Metan (CH4) är en av de viktigaste växthusgaserna i atmosfären och dess kraftiga ökning har bidragit till den uppvärmning som vi har upplevt fram till idag. Sedan mitten av 1980-talet påvisar mätningar att metantillväxten i atmosfären har börjat fluktuera från år till år. Orsakerna till detta är omstridda och ännu inte klargjorda. Under 2007 uppmättes en kraftig ökning i tillväxt som vaThe increasing atmospheric concentration of the greenhouse gas methane (CH4) is highly relevant for current and future global warming. Since the mid-1980s atmospheric measurements have revealed large interannual fluctuations in methane growth rate. However, the causes of this feature are still not well understood. In 2007, a peak in growth rate appears to have been particularly strong a

State Aid in the Financial Services Sector and the Implications of the Recent Financial Crisis

Financial services sector is fundamental to economic growth and development in all advanced economies. Financial services such as banking, savings and investment, insurance, and debt and equity financing constitute a nation’s economic engine by fulfilling three core functions in the economy. Firstly, these services provide financial intermediation functions between savers/investors that are lookin

Likelihood of confusion in the judgements of the European Courts and in the decisions of the OHIM

According to the ECJ, the assessment of the likelihood of confusion between two trade marks requires a consideration of numerous elements and, in particular: the degree of similarity between the trade marks and between the goods or services identified&semic the recognition of the trade mark on the market&semic the association which can be made with the used or registered sign. Moreover, it

The Efficiency and The Democratic Legitimacy of Commission's Policy Networks

The objective of the present work is to study the relationship between the European Commission and the so-called ''civil society'' through policy networks. It is considered whether a fair consultation of specialized partners can increase the level of democratic legitimacy and efficiency in the European Union. This hypothesis is considered in the light of the assumption that risk ma