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Nutritional constraints on Sphagnum-growth and potential decay in northern peatlands

1 In a 4-year fertilization experiment we studied the effects of increased nitrogen (N) or phosphorus (P) supply on productivity and potential decay in the acrotelm of Sphagnum-dominated Swedish peatlands at northern (low atmospheric N input: low-N site) and southern (high atmospheric N input: high-N site) sites. 2 During the experimental period, there was a severe summer drought at the high-N sit

Novel strategies for enzyme replacement with gene therapy in models of Parkinson’s disease

Popular Abstract in Swedish Ungefär 22 000 svenskar lever i dag med Parkinsons sjukdom som är en hjärnsjukdom där särskilda nervceller som normalt producerar signalsubstansen dopamin dör av okänd anledning. Dessa nervceller har en viktig funktion eftersom de möjliggör vår rörelseförmåga och brist på dopamin leder till rörelsenedsättning där patienten uppvisar symptomen långsamhet, skakningar, muskParkinson’s disease is a brain disorder characterized by loss of dopaminergic neurons in the midbrain, resulting in the characteristic motor symptoms: resting tremor, rigidity, akinesia and postural instability. Symptomatic treatment is based on reconstituting the loss of dopamine in the brain, primarily by oral administration of its precursor L-DOPA. Although this drug is effective in the early y

Laser-Driven Particle Acceleration - Improving Performance Through Smart Target Design

Popular Abstract in Swedish Många forskningsprojekt inom materialvetenskap, medicin eller grundläggande fysik kräver smala strålar av laddade partiklar som fungerar som provtagare för att undersöka materiens egenskaper. Dessa partiklar kan vara protoner, elektroner lättare joner. Relativt ofta, behöver de accelereras nästan upp till ljusets hastighet för att kunna tränga in tillräckligt djupt i prLaser-driven particle acceleration makes use of sub-picosecond, pulsed, high-power laser systems, capable of producing intensities ~10^{19} W/cm^2 at the laser focus to form plasmas, and use ultra-relativistic and nonlinear dynamics to produce quasistatic acceleration fields. This allows electrons to be accelerated to ~100 MeV over sub-centimetre distances, while protons may be accelerated to the

Prevalence of Tibiofemoral Osteoarthritis 15 Years After Nonoperative Treatment of Anterior Cruciate Ligament Injury: A Prospective Cohort Study.

BACKGROUND: The occurrence of osteoarthritis (OA), associated meniscal injuries, meniscectomy, and patient-related measures for patients treated nonoperatively after anterior cruciate ligament (ACL) injuries have not been well described in the literature in terms of natural history. HYPOTHESIS: Patients with ACL injury can achieve a low occurrence of tibiofemoral OA and good knee function when tre

Local and translational dynamics in DNA-lipid assemblies monitored by solid-state and diffusion NMR.

The influence of electrostatic interactions on the dynamic properties of complexes containing DNA and mixtures of cationic- (DDA) and zwitterionic (DLPC) lipids are studied by means of NMR. The systems are arranged in lamellar membrane stacks intercalated by DNA molecules. This is confirmed by 31P-NMR, where a superposition of an axially symmetric powder pattern arising from the phospholipid membr

Co-morbidity and mortality in Swedish patients with haemophilia - A register study

Haemophilia is an X-linked inherited recessive disorder affecting males. The increased risk of hemorrhage is explained by the deficiency in either coagulation factor VIII (haemophilia A) or IX (haemophilia B). The severity of haemophilia A and B is characterized by the bleeding pattern. For severe haemophilia bleeding is often spontaneous, mainly in muscles and joints. Since the 1950s the manifest

Altered chemokine levels in the cerebrospinal fluid and plasma of suicide attempters.

Chemokines constitute a class of small inflammatory proteins that control the chemotaxis of leukocytes. They are also present in the central nervous system (CNS) and contribute to diverse physiological functions, such as the regulation of cell migration, axonal growth and neuronal survival. It is to date not known whether chemokines in the CNS are affected in psychiatric disorders. In this study,

A trade-off between perceived predation risk and energy conservation revealed by an immune challenge experiment

Energy is typically a limiting factor for animals during boreal zone winters, when low temperatures increase the cost of thermoregulation at the same times as short day-lengths and snow cover constrain foraging opportunities. Under these circumstances animals use a suite of behavioural and physiological adaptations to avoid overnight starvation. However, it is poorly understood how such strategies

Redox Chemistry in Two Iron-Bentonite Field Experiments at Äspö Hard Rock Laboratory, Sweden: An XRD and Fe K-Edge XANES Study

Excavated bentonite from two large iron-bentonite field experiments at Aspo Hard Rock Laboratory in Sweden was investigated with respect to iron redox chemistry and mineralogy. The iron redox chemistry was studied by Fe K-edge X-ray absorption near edge structure spectroscopy and the mineral phases were studied using X-ray diffraction. Bentonite is to be used as a buffer material in high-level rad

Pathogenic paths? A time geographical approach in medical geography

Medical geography usually attempts to disentangle and explain the ecological and causal contexts of health, disease and environment by mapping spatial patterns of cases and potential pathogenic factors. However, many diseases are believed to show after long periods of latency , spanning years and even decades between initial exposure and clinical onset. In view of high spatial human mobility - in

Småhusägarnas syn på att köpa fjärrvärme. En studie av tillämpade försäljningsstrategier och kunders val vid konvertering från direktverkande el.

Summary This report presents results from the project ”Converting direct resistive electric heating into district heating - customer related aspects” conducted at the division of Efficient Energy Systems, Department of Energy Sciences, Lund University. The main objective of this study was to investigate how specific households within one housing area (Sandsbro in Växjö with 110 one-family houses)

Optimizing flow cytometric DNA ploidy and S-phase fraction as independent prognostic markers for node-negative breast cancer specimens

Developing a reliable and quantitative assessment of the potential virulence of a malignancy has been a long-standing goal in clinical cytometry. DNA histogram analysis provides valuable information on the cycling activity of a tumor population through S-phase estimates; it also identifies nondiploid populations, a possible indicator of genetic instability and subsequent predisposition to metastas

Ontogenetic and comparative aspects of cerebellar and motor development

During the course of development the motor repertoire of animals and humans alike go through dramatic changes. New motor patterns arise; movements become coordinated, improve in precision and are at the same time continuously calibrated to the changing body dimensions. The cerebellum is critical for movement coordination and adaptation in adults. Also, interfering with cerebellar development durin

Distal migration of stent-grafts after endovascular repair of abdominal aortic aneurysms

PURPOSE: To analyze patients after endovascular repair of abdominal aortic aneurysm (AAA) with respect to distal migration of stent-grafts and its underlying causes. MATERIALS AND METHODS: Sixty-five patients underwent endovascular repair between January 1994 and February 1997. There were seven women and 58 men, with a mean age of 71 years (range, 51-84 years). Three patients died in the periopera

Relation between the rate of tumour cell proliferation and latency time in radiation associated breast cancer.

Background: Patients with possible radiation induced cancer could be used to study if the rate of tumour cell proliferation is related to latency time. Such a finding could help researcher to find time periods when other initiating risk factors operate. Methods: Seventeen women with breast cancer, with a prior history of radiation treatment towards the parts or the whole breast, exclusive of the p

Resection of colorectal liver metastases: 25-year experience

The aim of this retrospective study was to analyze survival and prognostic factors in 111 consecutive patients undergoing curative resection of liver metastases from colorectal cancer. In addition, the time periods 1971-1984 and 1985-1995 were compared; criteria for first liver resection did not change with time, whereas the attitude toward re-resection was more aggressive during the latter period

Public administration developments in post-Soviet Central Asia

In the West, everybody is now talking about the economic and financial crisis. The term ‘’crisis” has become a buzzword within both academic and policy communities. There is an enormous upsurge of scholarly interest in the effects of this crisis on public administration systems, and the role that public administration plays in these processes. The underlying belief is that the public administratio

On the Regulation of Ornithine Decarboxylase

Popular Abstract in Swedish Polyaminer finns i alla levande celler, såväl i bakterier som i växter, djur och människor, och utgör en mycket viktig beståndsdel i dessa. Utan dessa polyaminer kan inte cellerna växa och dela sig. Polyaminerna putrescin, spermidin och spermin bildas i cellen från aminosyran ornitin. Till sin hjälp för denna bildning har cellerna ett enzym vid namn ornitindekarboxylas The polyamines putrescine, spermidine and spermine have been shown to be involved in cell growth and differentiation, and are considered to be crucial components of the living cell. The synthesis of polyamines in the cell is strictly regulated. The first and rate-limiting step in the biosynthesis of polyamines is catalysed by the enzyme ornithine decarboxylase (ODC). Mammalian ODC has a very fast

Wake visualization of a heaving and pitching foil in a soap film

Many fish depend primarily on their tail beat for propulsion. Such a tail is commonly modeled as a two-dimensional flapping foil. Here we demonstrate a novel experimental setup of such a foil that heaves and pitches in a soap film. The vortical flow field generated by the foil correlates with thickness variations in the soap film, which appear as interference fringes when the film is illuminated w