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The pineal organ is the only differentiated photoreceptor organ present in embryos and early larvae of the Atlantic halibut (Hippoglossus hippoglossus). We investigated the molecular identity of opsins in the pineal organ, and their expression during different life stages. Using RT-PCR we identified two 681-bp gene sequences, named HPO1 and HPO4, in cDNA from adult pineal and whole embryos. The pr

BACKGROUND: Frequent hyperglycemic episodes are increasingly being associated with an increased risk of type 2 diabetes and cardiovascular disease. OBJECTIVE: We studied the extent to which acute glycemia and glycemia after subsequent meals can be modulated by the characteristics of cereal foods, such as glycemic index (GI) and content of indigestible carbohydrates. DESIGN: Twelve healthy subjects

Context. The first release of astrometric data from Gaia is expected in 2016. It will contain the mean stellar positions and magnitudes from the first year of observations. For more than 100 000 stars in common with the HIPPARCOS Catalogue it will be possible to compute very accurate proper motions due to the time difference of about 24 years between the two missions. This Hundred Thousand Proper

Objectives: A potential role in cancer biology is suggested for YKL-40 (CHI3L1, HC gp-39). The purpose of this study was to evaluate the clinical value of serum YKL-40 (sYKL-40) in multiple myeloma (MM) and to examine YKL-40 expression in malignant plasma cells (MM PCs). Methods: sYKL-40 was measured by enzyme-linked immunosorbent assay (ELISA) in 82 patients with newly diagnosed MM. YKL-40 expres

‘Nordic noir’ has increasingly become the prevalent term in the English-speaking world when referring to contemporary crime fiction – books, television serials and feature films – from the Nordic countries. With its unexpected international appeal and unforeseen longevity, the phenomenon has been the subject of, for instance, popular guide books and television documentaries for international audie

Stroke causes life long disabilities where few therapeutic options are available. Using electrical and magnetic stimulation of the brain and physical rehabilitation, recovery of brain function can be enhanced even late after stroke. Animal models support this notion, and housing rodents in an enriched environment (EE) several days after experimental stroke stimulates lost brain function by multise

Background. Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous group of B-cell lymphomas. Five clinical adverse risk factors are merged into the International Prognostic Index (IPI), which is the major tool for prognostication. In contrast to Hodgkin's lymphoma, gender is not considered as an adverse risk factor for DLBCL patients. As we clinically had observed a very good survival rate in y

Popular Abstract in Swedish Bakgrund Man kan fråga sig varför en hel avhandling handlar om något så ovanligt som akut mastoiditit hos barn. Det är den vanligaste komplikationen till öroninflammation men drabbar bara 20-60 barn per år i Sverige. Öroninflammation däremot är en infektion som är så vanlig att nästan alla har haft åtminstone en sådan som barn. I Sverige diagnostiseras upp emot 200 000 One of the greatest threats to society today is the development of bacterial resistance to antibiotics. It is commonly accepted that this is mainly due to the use of antibiotics. Acute otitis media (AOM) is responsible for the highest number of antibiotic prescriptions to children although it is in most cases a self-limiting disease. Nevertheless, complications do occur in some case and the most c

Popular Abstract in Swedish Två av de viktigaste polyaminerna påträffades redan i slutet av 1600-talet, som kristaller i tjursperma och har därför fått namnen spermin och spermidin. Dessa aminer bildas från en annan substans, putrescin, som först isolerades från ruttnande kött. Namnet putrescin kommer från engelskans putrefaction, som betyder förruttnelse. Polyaminer, som kemiskt sett är positivt The polyamines putrescine, spermidine and spermine are essential for cell growth and differentiation. The biosynthesis of polyamines are tightly regulated by feedback mechanisms involving two enzymes, namely ornithine decarboxylase (ODC) and S-adenosylmethionine decarboxylase (AdoMetDC). This thesis deals with the mechanisms behind the polyamine-mediated feedback control of these enzymes. The poly

The dissertltion is a cultural-historical analysis of the feast of the Lord of May in a complex and socially conditioned setting. The method follows that of the historically oriented ethnology of the Munich school. As regards theory, I have been inspired by the civilization theory of Norbert Elias and by Robert Darnton's studies of groups of actors and their strategies. I have also found support i

This dissertation studies the effects that the use of a word-processing program can have on pupils' writing. The study was conducted with a consideration of the context in which the writing was done. It examined not just changes in the quality of the pupils' writing but also the attitudes of pupils, teachers, and parents to computer-aided writing. In addition, it studied the functional reliability

Background: Autism spectrum disorders (ASD) are a group of severe childhood neurodevelopmental disorders with still unknown etiology. One of the most frequently reported associations is the presence of recurrent de novo or inherited microdeletions and microduplications on chromosome 16p11.2. The analysis of rare variations of 8 candidate genes among the 27 genes located in this region suggested SE

Objective This study provides the summary of current knowledge about migrant work in agriculture available from journal articles, books, reports and other relevant academic publications, focusing on political, economic, legal, social and medical aspects of migrant work in agriculture. Methods A systematic search was carried out on the LibHub and Google Scholar databases in order to compile the e

Surfaces subjected to rolling and sliding contacts may suffer from contact fatigue. The cam and roller follower mechanism is a typical rolling and sliding contact. This thesis deals with the running in aspects to avoid high stress variation that leads to fatigue wear and the aspect of what happens to indentation damages that occurs on the surface if there are any particles in the lubricant. The pa

Popular Abstract in Swedish Den främsta orsaken till att cancer kan leda till döden är att tumörceller växer in i angränsande vävnad (invasiv) och tar sig in i blodet eller lymfsystemet och på så sätt sprids (metastaserar) till andra ställen i kroppen och stör funktionen i livsviktiga organ dvs tumören får ett aggressivt växtsätt. Det är därför viktigt, både ur prognostisk och terapeutisk synvinkeThe progressive process of tumour invasion and generation of metastases is the primary cause of death for most patients with cancer. Some of the regulatory components of this progressive process are adhesion, migration, and proteolysis. Urokinase -type plasminogen activator (u-PA) is a serine protease associated with tissue remodelling, cellular invasiveness, matrix degradation, angiogenesis, and

Popular Abstract in Swedish Rätten till domstolsprövning är en grundläggande rättighet som förekommer i alla demokratiska stater. Utgångspunkten är att alla har rätt att få sina tvister prövade av en domstol i ett förfarande som uppfyller vissa kvaliteter, en rättvis rättegång, och att staten har ett ansvar att tillhandahålla förutsättningar för sådana tvistlösningsförfaranden inför domstol. DäremOne of the most fundamental rights in any democratic state is the right of access to court. Every individual shall have the right to bring legal disputes before a court, in a proceeding with specifically defined characteristics, a fair trial, and the state is responsible for supplying the conditions and prerequisites to carry out this dispute resolution process in a court of law. However, this rig

In this essay, I discuss two major theoretical discourses of modernity, namely, of classical modernity and postmodernity. Moreover, I aim at a proposition of a possible historical relation between those two discourses of crucial importance to modernity’s intellectual history. This historical connection is founded on what I call the principle of insufficient reason. The principle of insufficient

The aim of this thesis was to study the chemical communication involved in aggressive and reproductive behaviours in the European lobster (Homarus gammarus). Both male and female H. gammarus established and maintained dominance, but the sexes used different strategies for dominance maintenance. Male losers recognised individual fight opponents and avoided them but fought actively against unfamili

Information about genetic variation has been collected for some 20 years into registries, known as locus specific databases (LSDBs), which nowadays often contain information in addition to the actual genetic variation. Several issues have to be taken into account when considering establishing and maintaining LSDBs and these have been discussed previously in a number of articles describing guidelin

Here we explore two new tree-ring parameters, derivedfrom measurements of wood density and blue intensity(BI). The new proxies show an increase in the interannualsummer temperature signal compared to establishedproxies, and present the potential to improve long-term performance.At high latitudes, where tree growth is mainlylimited by low temperatures, radiodensitometric measurementsof wood density