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År 2006 valde den svenska regeringen att tillsätta en utredning för att kartlägga omfattningen av den vanvård som skett i den sociala barnavården. Utredningen bedrevs främst genom intervjuer med frivilliga, som ville berätta om vad de utsatts för i sin barndom. Över 1000 personer blev intervjuade, det stora intresset var inte väntat utan utredningen överskred sina tidsramar både en och två gånger.The Swedish government initiated an inquiry in 2006 to survey the extent of serious abuse or neglect of children in social care. The inquiry took place primarily through interviews with volunteers who wanted to share what had happened to them in their childhood. More than 1000 people were interviewed, the huge interest was not expected and the time frame for the inquiry had to be extended not once

Sammanfattning Våldtäkt har sedan länge varit kriminaliserat, men dess innebörd och syftet bakom kriminaliseringen har varierat. Under 1800-talets slut var det främsta syftet att upprätthålla familjens, i synnerhet mannens, ära. Inte förrän 1965 blev våldtäkt inom äktenskap kriminaliserat, då kvinnans sexuella integritet ställdes i fokus. Därefter förstärktes den sexuella integriteten ytterligareSummary Rape has been criminalized for a long time, but the meaning and intention has been shifted. During the end of 1900th century the primary intention was to enforce the honour of the family, particularly that of the man. Not until 1965 rape became criminalized within marriage, as the sexual integrity of women came into focus. Subsequently the sexual integrity was enhanced by expanding 6 chap

Populärvetenskaplig sammanfattning Strukturbioinformatik och datorgrafik Proteiner bygger upp våra muskler, hud, hår m.m. och fungerar som katalysatorer (enzymer) för reaktioner som behövs för livet. Våra gener kodar för proteiner som utför funktioner i kroppen. Bioinformatik handlar om att studera det genetiska materialet hos människor och andra organismer. Strukturbioinformatik riktar in sig Abstract This Master Thesis explores a variety of approaches to protein structure comparision : CLICK, BetaSuperPoser, MAMMOTH, Minkowski Sum Boundary Calculation, 3DSurfer / Zernike Descriptors, Spherical Harmonics, D2 Shape (distance histogram) and ProBiS. The methods are categorized according to how they function and the meaning of their output parameters, in particular RMSD, is discussed. We

This special issue contains a collection of papers that study how children are affected by their sibship size, using anthropometric data. The varied results provide a wealth of new knowledge and show that this influence is context-specific. In this paper I discuss the methodological challenges that we will encounter continuing research on resource dilution in families. The most important challenge

Background: The aim was to develop a theoretical framework for how errors in estimated activities propagate to a dispersion in time-integrated activity in radionuclide-therapy dosimetry and how this affects the comparison of radionuclide-therapy dosimetry schemes. Methods: Formulae for the variance of relative errors of estimated time-integrated activities and relative differences in time-integrat

Upon hearing the phrase Some cats meow, a listener might pragmatically infer that 'Some but not all cats meow'. This is known as a scalar implicature and it often arises when a speaker produces a weak linguistic expression instead of a stronger one. Several L2 studies claim that pragmatic inferences are generated by default and their comprehension presents no challenges to L2 learners. However, th

Studies on cortical function have been a cornerstone in research trying to understand our brains for a long time. For many years now a basic feature of cortical processing has been the idea of a functional localization, with different areas or even neurons in the cortex having clear, individual, functions. This idea has been challenged from the outset, and with new methods to study the cortex the

Background: We investigated the impact of time to adjuvant chemotherapy (AC) on survival after surgical resection (<8 weeks or 8–16 weeks) for patients with non-small cell lung cancer (NSCLC) by applying a target-trial emulation. Material and Methods: We used Swedish population-based healthcare registries to emulate a hypothetical target trial, with treatment arms of ‘initiate AC <8 weeks postoper

This study discusses the European Union´s influence regarding the Cyprus Conflict since 1998, when the EU began the official membership negotioations with Cyprus. The first aim of the study is to investigate in what way the EU has tried to practice influence concerning the Greek- and Turk Cypriots, but also Turkey, since Turkey is seen as a relevant party in the conflict. The second aim of the stu

The focus of this thesis is a specific part of Swedish library policy called library plans. A library plan is a political document created with the purpose of constituting a platform for co-operation between different library systems within a municipality, e.g. through determining and analysing the needs for library activities within municipalities in Sweden. This thesis´ aim is to investigate wh

Optical genome mapping in nanochannels is a powerful genetic analysis method, complementary to deoxyribonucleic acid (DNA) sequencing. The method is based on detecting a pattern of fluorescent labels attached along individual DNA molecules. When such molecules are extended in nanochannels, the labels create a fluorescent genetic barcode that is used for mapping the DNA molecule to its genomic locu

The overall tumour incidence and breast cancer incidence related to hormone replacement therapy (HRT) were followed in a population-based cohort of 29 508 women, aged 25-65 when interviewed in 1990-92. By the end of the follow up in December 1999, there were 226 611 person-years of observation. A total of 1145 malignant tumours were recorded (expected 1166.6; SIR = 0.98, 95% CI 0.93-1.04). There w

Joint diseases are often characterized by inflammatory processes that result in pathological changes in joint tissues, including cartilage degradation and release of components into the synovial fluid. The complement system plays a central role in promoting the inflammation. Because several cartilage proteins are known to interact with complement, causing either activation or inhibition of the sys

OBJECTIVE: The objective of this nationwide study was to analyze how functional status and socioeconomic status affect return to work (RTW) among younger patients with first-time stroke in a Sweden.MATERIAL AND METHODS: This register-based cohort study included employed patients aged 25-55 with first-time stroke between 2008 and 2011 and primary outcome was RTW within 1 year after stroke. Data reg

Glycosaminoglycans (GAGs) are polysaccharides produced by essentially all mammalian cells. Due to their enormous structural diversity, they are involved in many biological processes both in health and disease, including all stages of tumor progression. GAGs are normally attached to a core protein as a part of a proteoglycan; however, GAG biosynthesis can be induced by compounds composed of a xylos

Background: Optimal adjunctive therapy in ST-segment elevation myocardial infarction (STEMI) patients treated with primary PCI (PPCI) remains a matter of debate. Our aim was to compare the efficacy and safety of bivalirudin to unfractionated heparin (UFH), with or without glycoprotein IIb/IIIa inhibitors (GPI) in a large real-world population, using data from the Swedish national registry, SWEDEHE

A challenge for the theorising of climate justice is that even when the agents whose actions are supposed to be regulated are cooperative and act in good faith, they may still disagree about how the burdens and benefits of dealing with climate change should be distributed. This article is a contribution to the formulation of a useful role for normative theorising in light of this bounded nature of