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The cerebellar cortex is necessary for adaptively timed conditioned responses (CRs) in eyeblink conditioning. During conditioning, Purkinje cells acquire pause responses or "Purkinje cell CRs" to the conditioned stimuli (CS), resulting in disinhibition of the cerebellar nuclei (CN), allowing them to activate motor nuclei that control eyeblinks. This disinhibition also causes inhibition of the infe
The Palaeocene arctic supported a vegetation type quite distinct from the tundra and polar desert of today. Here we demonstrate, through the palynological record, the structure of this extinct vegetation and its dynamics over this period. The Late Palaeocene coal-bearing units of the Sagwon Bluffs on Alaska's North Slope (present latitude 69 degrees N) are predominantly fine-grained, non-marine an
The article discusses the identity, roles, and duties of the professional historian in an era in which the historical dimension is no longer a historian's monopoly. It is argued that the standard modern framework of understanding a historian as someone highly specialized in the production of 'new' history has to give way to a new understanding that situates the historian in historical culture, whi
In a broad range of species-including humans-it has been demonstrated that telomere length declines throughout life and that it may be involved in cell and organismal senescence. This potential link to ageing and thus to fitness has triggered recent interest in understanding how variation in telomere length is inherited and maintained. However, previous studies suffer from two main drawbacks that
Background: Early developmental conditions can influence within- and among-brood variation in the timing of hatching/birth, which has been shown to affect offspring survival, growth, and reproductive success across a range of species. Problem: How does within- and among-litter variation in the timing of birth affect offspring growth and survival in Egernia whitii? Organism: Egernia whitii, a l
Abstract in Spanish A pesar de que el mercado laboral sueco ha permanecido relativamente intacto durante la crisis económica en los últimos seis años, la integración de personas con capacidad laboral reducida a causa de discapacidades es significativamente menor que la de otros grupos sociales. La legislación sueca sobre discapacidad y trabajo cubre varios aspectos en medidas de integración, antidEven though the Swedish labour market has been more or less intact during the financial crisis in the past six years, persons with reduced working capacity due to disabilities are significantly less integrated in the labour market than other groups in society. Swedish legislation on disability and work provides for a number of different aspects of integrative measures, anti-discrimination and prov
Increased temperatures and concomitant changes in vegetation patterns are expected to dramatically alter the functioning of northern ecosystems over the next few decades. Predicting the ecosystem response to such a shift in climate and vegetation is complicated by the lack of knowledge about the links between aboveground biota and belowground process rates. Current models suggest that increasing t
The purpose of this study was to explore neuroretinal transplantation in a large animal model of severe retinitis pigmentosa and to establish graft development, long-term survival, graft-host integration, and effects on the host retina. Methods Rhodopsin transgenic pigs, aged 6 months, received in one eye a fetal full-thickness neuroretinal sheet in the subretinal space by means of vitrectomy and
This study is concerned with the statistical analysis of tick-borne encephalitis (TBE) antibody decrease after vaccination. The objective is to derive conclusions about protection duration of vaccination. TBE is a serious infection affecting the central nervous system and Austria is a high risk region of TBE. Active immunization by vaccination prevents TBE and nowadays 88% of Austria's populat
Couplings of microscopic stochastic models to deterministic macroscopic ordinary and partial differential equations are commonplace in numerous applications such as catalysis, deposition processes, polymeric flows, biological networks and parametrizations of tropical and open ocean convection. In this paper we continue our study of the class of prototype hybrid systems presented in [8]. These mode
Patent counts have been extensionally used to measure the innovative capacities of countries. However, since economic values of patents may differ, simple patent counts may give misleading rankings, if the patents of one country are on average more valuable than those of another. In the literature several methods have been proposed, which shall adjust for these differences. However, often these do
Power, influence and employee empowerment are topics which have been of great interest to many researchers for a long time. However, there has been limited research on upward influence and employees' perceptions of empowerment. In addition, there has almost been no research on the relations between upward influence and employee empowerment. This thesis deals with these relations, and how they
The aim of the paper is to discuss some of the basic elements of the legal system in EC law in comparison with the EEA Agreement. The conclusions will have special reference to Icelandic law. The reason for this approach is that the EEA Agreement is closely linked with EC law. Therefore it is necessary to begin approaching the basic rules within the EC in order to better understand the EEA system
A thesis about the right to life in internal armed conflict must necessarily take both human rights law and humanitarian law into account. Human rights law, which has codified the right to life in its main instruments, is applicable both in time of peace and in time of war, whereas humanitarian law is only applicable during armed conflict. The question is thus how these two branches of law influen
In order to reinstate interest and motivation for learning foreign languages (FLs) other than English, the Swedish government has recently reformed the admissions system to higher education. Upper secondary students who continue with the FL learnt in secondary school are rewarded with extra credits that considerably enhance their grade point average (GPA). The purpose of this interview-based study
Mounting evidence shows that early-life adversity negatively affects morbidity and survival in late life, but knowledge is limited about effects on health in mid-life. To deepen our understanding of the long-term consequences of disease exposure in early life, we study women’s reproductive outcomes and survival. Using the Scanian Economic Demographic Database (SEDD) and Swedish administrative regi
Background Influenza and other respiratory viruses promote Streptococcus pneumoniae proliferation in the upper respiratory tract. We sought to investigate for what we believe is the first time, the effect of intranasal live attenuated influenza vaccine (LAIV) on nasopharyngeal S pneumoniae density in a low-income to middle-income country population with high pneumococcal carriage rates. Methods I
Aims/hypothesis: The rapid remission of type 2 diabetes by a diet very low in energy correlates with a marked improvement in glucose-stimulated insulin secretion (GSIS), emphasising the role of beta cell dysfunction in the early stages of the disease. In search of novel mechanisms of beta cell dysfunction after long-term exposure to mild to severe glucotoxic conditions, we extensively characterise
Capture into mean motion resonance (MMR) is an important dynamical mechanism because it shapes the final architecture of a planetary system. We simulate systems of two or three planets undergoing migration with varied initial parameters such as planetary mass and disk surface density and analyse the resulting resonant chains. In contrast to previous studies, our results show that the disk properti
Surtsey island was formed in a volcanic eruption south of Iceland in 1963 – 1967 and has since then been protected and monitored by scientists. It is the youngest island in the Vestmannaeyjar archipelago. The archipelago is of volcanic origin, but the other islands are ca. 5 000 to 40 000 yrs old. The first two moss species were found on Surtsey as early as 1967 and several new bryophyte species w
