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Retained Metabolic Flexibility of the Failing Human Heart

Background: The failing heart is traditionally described as metabolically inflexible and oxygen starved, causing energetic deficit and contractile dysfunction. Current metabolic modulator therapies aim to increase glucose oxidation to increase oxygen efficiency of adenosine triphosphate production, with mixed results. Methods: To investigate metabolic flexibility and oxygen delivery in the failing

Where access and benefit-sharing comes from: A historical overview

The international legal system of access and benefit-sharing of genetic resources (or ABS) under the Convention on Biological Diversity (CBD) is an ever-evolving field as its material, temporal and activity scope is still under discussion to meet the needs of the advancement of research and development activities as well as the questions of fairness and equity that evolve with them. Activities, su

Heat flux reconstruction by inversion of experimental infrared temperature measurements – Application to the impact of a droplet in the film boiling regime

An Inverse Heat Conduction Problem (IHCP) is considered in order to estimate the transient heat flux extracted from a hot solid surface by an impinging droplet. The resolution of the IHCP is made with the so-called quadrupole method, which provides an analytical expression of the temperature and the heat flux at the front surface of the solid wall, where the drop impact takes place. In the experim

Transgender and gender diverse people's experience of non-transition-related health care in Sweden

Introduction: The transgender population is a marginalized group in society and research suggests that they experience significant barriers when accessing health care. However, little is known about transgender and gender-diverse people and their experiences of encounters with healthcare professionals in Sweden. Aim: To explore transgender and gender-diverse people's experiences of accessing healt

Acoustic impedance matched buffers enable separation of bacteria from blood cells at high cell concentrations

Sepsis is a common and often deadly systemic response to an infection, usually caused by bacteria. The gold standard for finding the causing pathogen in a blood sample is blood culture, which may take hours to days. Shortening the time to diagnosis would significantly reduce mortality. To replace the time-consuming blood culture we are developing a method to directly separate bacteria from red and

Can a teachable agent influence how students respond to competition in an educational game?

Learning in educational games is often associated with some form of competition. We investigated how students responded to winning or losing in an educational math game, with respect to playing with or without a Teachable Agent (TA). Students could choose between game modes in which the TA took a more passive or active role, or let the TA play a game entirely on its own. Based on the data logs fro

Post-truth Politics, Performatives and the Force

This paper on post-truth politics argues that to the extent that one wants to understand political discourses generally (post-truth political discourses in particular) it is crucial to see them as circulating talk that performs rather than reports. This implies a shift in focus. Many react strongly to ‘post-truth’ assertions by appealing to evidence, objectivity, facts and truth. In this paper it

A Historical Perspective on Ageing and Capability

This chapter discusses the value of a capability approach in historical research on older people. Historians are generally focused on studying continuity and change over time. Their research often aims at explaining how and why certain phenomena appear and take different shapes. Capability is a way of capturing an individual’s ability to live a meaningful life, or a life that they perceive as good

Multicenter global early feasibility study to evaluate total endovascular arch repair using three-vessel inner branch stent-grafts for aneurysms and dissections

PURPOSE: To evaluate the outcomes of total endovascular aortic arch repair using three-vessel inner branch stent-grafts for aneurysms and chronic dissections.METHODS: We reviewed the clinical data and outcomes of consecutive patients treated by total endovascular aortic arch repair at eight academic centers using three-vessel inner branch stent-grafts (William Cook Europe, Bjaeverskov, Denmark) be

Workaway : Cultivating conviviality within mobility, sociality and daily living

This ethnographic research on ‘Workaway’ investigates new forms of mobility experiences, in between travel and migration, which are used by a plethora of types of people (both hosts and guests) with different motivations (learning new skills and experiences), needs, ambitions, dreams, as well as/or life-time crisis, and different types of problems (e.g. lack of finances, no opportunity or prospect

Interventions for treating genital Chlamydia trachomatis infection in pregnancy

Background: Genital Chlamydia trachomatis (C.trachomatis) infection may lead to pregnancy complications such as miscarriage, preterm labour, low birthweight, preterm rupture of membranes, increased perinatal mortality, postpartum endometritis, chlamydial conjunctivitis and C.trachomatis pneumonia.This review supersedes a previous review on this topic. Objectives: To establish the most efficacious

Publishing E-RDF linked data for many agents by single third-party server

Linked data is one of the most successful practices in semantic web, which has led to the opening and interlinking of data. Though many agents (mostly academic organizations and government) have published a large amount of linked data, numerous agents such as private companies and industries either do not have the ability or do not want to make an additional effort to publish linked data. Thus, fo

Kant on Freedom and Obligation Under Law

One of the more puzzling aspects of Kant’s political thought is his insistence on the duty to obey even oppressive rulers combined with his belief in the republic as the only rightful constitutional form. In arguing that resisting oppressive power is as wrong as seizing it, Kant seems committed to the awkward position of denouncing as unrightful any attempts made by the people to establish the onl

Impact of Human Papillomavirus (HPV)-6/11/16/18 Vaccine on All HPV-Associated Genital Diseases in Young Women.

Background The impact of the prophylactic vaccine against human papillomavirus (HPV) types 6, 11, 16, and 18 (HPV6/11/16/18) on all HPV-associated genital disease was investigated in a population that approximates sexually naive women in that they were "negative to 14 HPV types" and in a mixed population of HPV-exposed and -unexposed women (intention-to-treat group). Methods This analysis studied

Om att mobilisera familjer - för barns hälsa och utveckling i skolan

The aim of this study was to examine what the preventative operation Family mobilization, that involves both social service and school, contributes with for the families and the pedagogues that are involved. This regarding similarities and differences between the intentions and the realization of the operation, together with the cooperation between the home and the school focusing on participation

Värdering av förvaltningsfastigheter till verkligt värde - En explorativ studie om den externa värderarens roll

Syfte: Studiens ändamål är att utreda de externa värderarnas syfte för användarna av fastighetsbolagens finansiella rapporter. Vi ämnar även undersöka till vilken grad de externa värderarna är oberoende i sina värderingar och analysera den informationsasymmetri som råder i branschen. Metod: Uppsatsen är en kvalitativ intervjustudie av explorativ karaktär och ämnar undersöka externa värderares syfPurpose: The study's purpose is to investigate the external appraisers purpose for the users of real estate companies' financial statements. We also intend to investigate to what extent the external appraisers are independent in their valuations and analyze the information asymmetry that exists in the industry. Methodology: The thesis is a qualitative interview study of a comparative natu

Arbetstagare och upphovsman - vilket rättsligt skydd finns?

Arbetstagare som presterar upphovsrättsliga verk inom ramen för en anställning omfattas av två huvudsakliga regelverk: det arbetsrättsliga och det immaterialrättsliga. Inget av regelverken innehåller uttryckliga bestämmelser för sådana verk som uppkommer under en anställning, med undantag för bestämmelsen i 40 a § URL avseende datorprogram. Vägledning får därför sökas i andra rättskällor. Avseende

Familjestämning utifrån tilltro och känslor - en studie av ett testinstrument med syfte att mäta familjemående

Syftet med studien var att utarbeta ett nytt testinstrument för att mäta familjemående samt att undersöka samband mellan familjemående och individuellt mående med fokus på depressiva symtom, och eventuella könsskillnader, vilket gjordes genom testinstrumenten Familjestämning och CES-D. Materialet som utvärderades inhämtades från 168 studenter vid Socialhögskolan och Psykologiska institutionen, LunThe aim of the study was to develop a new test instrument for measuring family mood as well as to investigate the relationship between family mood and individual mood with a focus on depressive symptoms and possible gender differences, which were measured by the Family Mood Assessment and CES-D test tools. The material evaluated was obtained from 168 students from the School of Social Work and fro

Demokratibegreppet hos Elias Canetti - formering av ett perspektiv

When Elias Canetti was awarded the Nobel Prize in Literature in 1981 it made him famous to a wider reading public, but his personal acquaintance with a range of European writers had already made him one of the central intellectuals of his time. His works include the novel Auto da Fé and his tour de force, a collection of aphorisms called Crowds and Power. Despite examining the eponymous themes and

”Det är ingen sexualitet jag träffar” : En kvalitativ studie om socialarbetares erfarenheter av bemötande inom ideella sektorn utifrån ett queerteoretiskt perspektiv

The aim of this study was to analyze social workers description of their care-support of the receivers through a queer-theoretical perspective within two non-profit organizations. The two non-profit organizations are working with sexual health in Sweden. Six qualitative semi-structured interviews were conducted. The social worker’s experiences with giving care-support were analyzed through queer t