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Transitions from trees to cycles in adaptive flow networks

Transport networks are crucial to the functioning of natural and technological systems. Nature features transport networks that are adaptive over a vast range of parameters, thus providing an impressive level of robustness in supply. Theoretical and experimental studies have found that real-world transport networks exhibit both tree-like motifs and cycles. When the network is subject to load fluct

On the Anarchic Organisation of Cinematic Spaces : Evoking Spaces beyond Cinema

This research engages with the space beyond cinema and comprises a futuristic vision about the condition of cinema.My work takes a conceptual approach that considers cinema in an architectural sense and as an instrument, where the environment, the screen, and the projection can be combined or pushed forward to create another spatiotemporal dimension that is concurrent with and beyond the context o

Informal but Planned Settlements: A Case in Guayaquil

Urbanization has been very strong since the middle of the 1900s and from 2007, 50% of the population in the world has become urban. Today almost one third of this urban population, around 1 billion, is living in areas classified as slums with substandard housing and a lack of land rights. In some cases more than 50% of the growth of cities in developing countries has been implemented by the inform

Efficacy of Esomeprazole in NSAIDs Induced Gastric Ulcer: A Meta-Analysis

Background: Gastric ulcers are painful sores with discontinuity in the entire thickness of stomach lining. Proton pump inhibitors (PPIs) are among the major classes of drugs used in treatment of gastric ulcers by inhibiting H+/K+ATPase pump thus reducing acid secretion. The prototype of PPIs is omeprazole, one of its new derivatives, esomeprazole is known to have superior activity against NSAIDs i

Differences in unmet healthcare needs between public and private primary care providers : A population-based study

Aims: To investigate if any differences in unmet healthcare needs between persons registered at public and private primary care providers exist in Skåne (southernmost Sweden). Methods:The 2012 public health survey in Skåne was conducted with a postal questionnaire and included 28,029 respondents aged between 18 and 80 years. The study was cross-sectional. If the responder in the last three months

Visible light induction of an electron paramagnetic resonance split signal in photosystem II in the S 2 state reveals the importance of charges in the oxygen-evolving center during catalysis : A unifying model

Cryogenic illumination of Photosystem II (PSII) can lead to the trapping of the metastable radical Y Z •, the radical form of the redox-active tyrosine residue D1-Tyr161 (known as Y Z). Magnetic interaction between this radical and the CaMn 4 cluster of PSII gives rise to so-called split electron paramagnetic resonance (EPR) signals with characteristics that are dependent on the S state. We report

The solvability and subellipticity of systems of pseudodifferential operators

The paper studies the local solvability and subellipticity for square systems of principal type. These are the systems for which the principal symbol vanishes of first order on its kernel. For systems of principal type having constant characteristics, local solvability is equivalent to condition (Ψ) on the eigenvalues. This is a condition on the sign changes of the imaginary part along the oriente

Social rights in the shadow of poor relief – social assistance in the universal Swedish welfare state

The idea of a European social citizenship is being developed by the EU to provide a minimum safety net. Questions about social citizenship are of fundamental importance in people’s everyday lives. Social assistance is a central dimension when studying social citizenship. Before discussing in terms of a European social citizenship, we should determine whether we have a social citizenship at the nat

Generation of human cortical neurons from a new immortal fetal neural stem cell line.

Isolation and expansion of neural stem cells (NSCs) of human origin are crucial for successful development of cell therapy approaches in neurodegenerative diseases. Different epigenetic and genetic immortalization strategies have been established for long-term maintenance and expansion of these cells in vitro. Here we report the generation of a new, clonal NSC (hc-NSC) line, derived from human fet

Oncoretroviral gene transfer to NOD/SCID repopulating cells using three different viral envelopes

Background The aim of this study was to investigate gene transfer to human umbilical cord blood (CB) CD34(+)/CD38(low) and NOD/SCID repopulating cells using oncoretroviral vectors and to compare the transduction efficiency using three different viral envelopes. Methods CB cells were transduced on Retronectin using an MSCV-based vector with the gene for GFP (MGIN), which was packaged into three dif

Variability in muscle fibre areas in whole human quadriceps muscle: how to reduce sampling errors in biopsy techniques

A single biopsy is a poor estimator of the muscle fibre cross-sectional area (CSA) for a whole human muscle because of the large variability in the fibre area within a muscle. To determine how the sampling errors in biopsy techniques can be reduced, data on the CSA of type 1 and type 2 fibres obtained from cross-sections of whole vastus lateralis muscle of young men, have been analysed statistical

Reversed sexual dimorphism in tawny owls, Strix aluco, correlates with duty division in breeding effort

Even though most bird species with a raptorial feeding habit express varying extents of reversed sexual dimorphism (RSD: females bigger than males), the evolutionary basis for its maintenance, as well as its possible secondary consequences for the ecological adaptations of the different sexes, is debated. We studied pairs of tawny owls, Strix aluco (females 20% heavier than males), throughout the

Intrathecal cyclosporin prolongs survival of late-stage ALS mice

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by upper and lower motor neuron death with ascending paralysis leading to death. In a transgenic mouse model of ALS (SOD1-G93A) weakness appears at 3 months of age, and because of progressive paralysis leads to death by 5 months. Cyclosporin A (CsA) is well known, for its extracerebral effect, as an immunosuppressant

Fluorescence studies on the interaction between pyrene-labelled poly(acrylic acid) and cyclodextrins

The interactions, in aqueous media, between a pyrene-labelled polyelectrolyte poly(acrylic acid) (PAAMePy) with two different degrees of labelling and beta- and gamma-cyclodextrins (beta- and gamma-CD) were studied using absorption and fluorescence (steady-state and time-resolved) techniques. In addition to qualitative and quantitative parameters obtained from absorption and steady-state fluoresce

Osteopenia in alcoholics after tibial shaft fractures

A marked reduction of 40-70% in regional bone mineral density (BMD) has been reported after fractures of long bones, and this post-traumatic osteopenia may to some extent persist for several years, perhaps lifelong. In this cross-sectional study, we investigated whether prolonged alcohol abuse had any effect on the degree of post-traumatic osteopenia after isolated tibia shaft fractures, the ratio

Implementation and validation of an environmental feedback pool fire model based on oxygen depletion and radiative feedback in FDS

This paper has been aimed at implementing and validating a simplified environmental feedback fire model in FDS as a complement to more advanced pyrolysis models. The two main means of environmental feedback have been identified as the oxygen concentration close to the fuel base and the radiative feedback from the surrounding obstructions and smoke layer. The oxygen concentration at the fuel base h

POET: A Portable Approach to Minimizing Energy Under Soft Real-time Constraints

Embedded real-time systems must meet timing constraints while minimizing energy consumption. To this end, many energy optimizations are introduced for specific platforms or specific applications. These solutions are not portable, however, and when the application or the platform change, these solutions must be redesigned. Portable techniques are hard to develop due to the varying tradeoffs experie