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Laser trabeculoplasty in newly diagnosed multi-treated glaucoma patients

PURPOSE: To evaluate the intraocular pressure (IOP)-lowering effect of laser trabeculoplasty (LTP) in eyes which IOP had been substantially reduced by intensive topical treatment for one week.METHODS: Patients with newly diagnosed open-angle glaucoma were randomized to treatment with three IOP-lowering substances. One week later, 360° argon or selective LTP was performed. IOP was measured before L

Absolute dating of the L-chondrite parent body breakup with high-precision U–Pb zircon geochronology from Ordovician limestone

The breakup of the L-chondrite parent body (LCPB) in the mid-Ordovician is the largest documented asteroid breakup event during the past 3 Gyr. It affected Earth by a dramatic increase in the flux of L-chondritic material and left prominent traces in both meteorite and sedimentary records. A precise constraint on the timing of the LCPB breakup is important when evaluating the terrestrial biotic an

Cuban socialism at 60 : Old aspirations and new realities

Few revolutions have had such an impact in modern times as the Cuban Revolution in 1959. Numerous publications (books, articles, and dissertations) have been written about it. Opinions about it have diverged. The revolution has been an inspiration for many, contested and even detested by others. In 1961, the Cuban Revolution took a radical turn when Fidel Castro declared that the revolution was so

Contact Allergy to Fragrance Mix II and Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde : A Retrospective Study by International Contact Dermatitis Research Group

BACKGROUND: Fragrance mix II (FM II) is included in the baseline patch test series recommended by the International Contact Dermatitis Research Group (ICDRG). Hydroxyisohexyl 3-cyclohexene carboxaldehyde (HICC) is the most important sensitizer of the 6 fragrance materials included in FM II. Besides being a part of FM II, HICC is also tested separately in the ICDRG baseline series. OBJECTIVES: The

5-year mental health and eating pattern outcomes following bariatric surgery in adolescents : a prospective cohort study

Background: Mental health problems are prevalent among adolescents with severe obesity, but long-term mental health outcomes after adolescent bariatric surgery are not well known. We aimed to assess mental health outcomes over 5 years of follow-up after Roux-en-Y gastric bypass surgery in adolescents who participated in the Adolescent Morbid Obesity Surgery (AMOS) study. Methods: This was a non-ra

Implementation of Endoscopic Submucosal Dissection in a Western Institution

Endoscopic resection of colorectal polyps reduce morbidity and mortality from colorectal cancer (CRC).Endoscopic submucosal dissection (ESD) is a highly efficient and established method for treating advanced colorectal lesions in Asia, but experience of ESD in Western countries is limited. Large non-pedunculated colorectal lesions are prone to malignant transformation and it is therefore important

Social investment by popular demand? The electoral politics of employment-centered family policy

Employment-centered family policies enable parents to combine work and family, thereby improving work–life balance for individuals and families as well as increasing GDP. For these reasons, these policies constitute a central component of the social investment approach, a model for how to design social policies for contemporary societies. This study seeks to understand whether voters enable the ex

Crack widths in base restrained walls subjected to restraint loading

Cracks in concrete structures can have a negative impact on durability and aesthetic appearance. It is therefore important to estimate crack widths before construction, and to use suitable reinforcement amounts to limit crack widths. Crack widths are however hard to predict in restrained structures, as cracking reduces the stiffness, which in turn reduces the restraint and thereby the amount of cr

Women’s experience of the health information process involving a digital information tool before commencing radiation therapy for breast cancer : a deductive interview study

Background: Individuals undergoing radiation therapy for breast cancer frequently request information before, throughout and after the treatment as a means to reduce distress. Nevertheless, the provision of information to meet individuals needs from their level of health literacy is often overlooked. Thus, individuals information needs are often unmet, leading to reports of discontent. Internet an

Perinatal risk factors for developmental coordination disorder in children born extremely preterm

Aim: Children born extremely preterm frequently have developmental coordination disorder (DCD). We aimed to evaluate perinatal risk factors for DCD. Methods: Swedish national cohort study including 226 children born before 27 gestational weeks without major neurodevelopmental disabilities at 6.5 years. Outcome was DCD, defined as ≤5th percentile on the Movement Assessment Battery for Children-Seco

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In the current public discourse the phenomenon of insecurity is widely discussed since various kinds of social risks are becoming more widespread throughout European societies threatening biographical stability and status security. Given this there is a quest for a realignment of statEinterventions aiming at the (re-)production of stability and security. It is assumed that institutional arrangemen

Intraoperative Cytology for Video-Assisted Thoracic Surgery : A Quality Improvement Analysis

Background: Frozen section is a standard of care procedure during thoracic surgery when an immediate diagnosis is needed. An alternative procedure is intraoperative cytology. Video-assisted thoracic surgery is currently widely used for thoracic surgical procedures. The aim of this study was to assess intraoperative cytology together with frozen section for accuracy, turnaround time, and total resp

Construction of an ultrasound phantom with micrometer-sized wall-less vessels

The development of new ultrasound imaging technologies that aim to resolve objects smaller than the conventional ultrasounds diffraction limit calls for new types of phantoms to evaluate these technologies. When it comes to vascular flow phantoms, this becomes challenging due to the difficulty of manufacturing phantoms with vessels smaller than 1 mm in diameter. Here we describe a novel manufactur

Development of a core capability framework for qualified health professionals to optimise care for people with osteoarthritis : an OARSI initiative

Objective: Develop a generic trans-disciplinary, skills-based capability framework for health professionals providing care for people with OA. Design: e-Delphi survey. An international inter-professional Delphi Panel (researchers; clinicians; consumer representatives) considered a draft framework (adapted from elsewhere) of 131 specific capabilities mapped to 14 broader capability areas across fou

At the nexus of problem-solving and critical research

The analytical distinction between critical and problem-solving research is useful. At the onset of research, the latter takes the world as it is while the former questions it. Yet, in striving to integrate social and natural dimensions of sustainability such a distinction may surface as a methodological obstacle. We illustrate how combining critical with problem-solving approaches can help us ima

Implementation of the measure of case discussion complexity to guide selection of prostate cancer patients for multidisciplinary team meetings

Background: Multidisciplinary team meetings (MDTMs) provide an integrated team approach to ensure individualized and evidence-based treatment recommendations and best expert advice in cancer care. A growing number of patients and more complex treatment options challenge MDTM resources and evoke needs for case prioritization. In this process, decision aids could provide streamlining and standardize

Neither Fish, Nor Fowl : A New Way to a Fuller Understanding of the lex specialis Principle

International lawyers ascribe to the lex specialis principle three distinctly different meanings. Thus, lex specialis is referred to, first, as a norm designed to resolve conflicts between entire categories of norms; secondly, as a norm designed to resolve conflicts on a case-by-case basis; and, thirdly, as a rule of interpretation designed to avoid the occurrence of normative conflicts, rather th

Pre- and postnatal exposure to parental smoking and allergic disease through adolescence

OBJECTIVES: To examine the role of prenatal and postnatal second-hand tobacco smoke (SHS) exposure on asthma, rhinitis, and eczema development up to 16 years of age.METHODS: A birth cohort of 4089 children was followed for 16 years. Information on parental smoking habits, lifestyle factors, and symptoms of allergic disease was gathered using repeated parental questionnaires. Generalized estimating