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We investigated the pragmatic effects of gesture-speech lag by asking participants to reconstruct formations of geometric shapes based on instructional films in four conditions: sync, video or audio lag (±1,500 ms), audio only. All three video groups rated the task as less difficult compared to the audio-only group and performed better. The scores were slightly lower when sound preceded gestures (
The quinoline-3-carboxamides (Q compounds) are a family of small molecules with immunomodulatory functions that have shown efficacy in various murine models of inflammatory diseases. One such compound has demonstrated antitumor effects in murine models. Q compounds bind to S100A9, thereby preventing its ligation to TLR4 and RAGE. S100A9 is a small molecule which has shown to have a role in the est
Previous positron emission tomography (PET) studies have quantified filamentous tau pathology using regions-of-interest (ROIs) based on observations of the topographical distribution of neurofibrillary tangles in post-mortem tissue. However, such approaches may not take full advantage of information contained in neuroimaging data. The present study employs an unsupervised data-driven method to ide
A three-language book Swedish, English and Arabic, that includes the information about the project entitled: Photograph and Film for freedom and Democracy, that funded by Swedish Institute, and Organized by Ibn Rushd Association and pertnership with Yemeni Idintity Organization and Lund University, among other partners. Also, it contains the thirty photos that have been shown in Yemen Art Exhibit
The problem of identifiability of processes using measurements obtained under closed loop operation is treated. Single input-single output systems are considered. It is assumed that the feedback is time invariant, linear and noise free. It is also assumed that no external input signal is injected. Conditions, which are simultaneously necessary and sufficient for identifiability are derived. The re
PURPOSE OF REVIEW: In the past decades, cysteinyl leukotrienes (CysLTs) and prostaglandin D2 have been recognized as key mediators of asthma and comorbid conditions for their potent broncho-active and proinflammatory properties. However, both the development and initial positioning of small molecules targeting these lipid mediators [i.e., leukotriene-synthesis inhibitors, CysLT-antagonists, and ch
A reduced kinetic mechanism for methanol combustion at spark-ignition (SI) engine conditions is presented. The mechanism consists of 18 species and 55 irreversible reactions, small enough to be suitable for large eddy simulations (LES). The mechanism was reduced and optimized using the comprehensive mechanism (AramcoMech 2.0) as a starting point, to maintain performance at stoichiometric condition
Low cost andin situfluoride detection by non-experts is importantfor the determination of drinking water safety in developing countries.Colour reagents can provide results quickly without expensiveequipment, but colorimetric fluoride indicators are often non-specific, complex to use or do not work in water. Here we showthat azulene–boronate indicators respond selectively to fluoride atconcentratio
Objectives: Gallstone disease (cholelithiasis) has a familial component, but detailed data on the modification of familial risk are lacking. Using nationwide hospital and population records, we aimed to determine detailed familial risks for medically diagnosed gallstone disease.Design: Subjects were obtained from the Multigeneration Register, which contains family data on the Swedish population, a
Nitrogenase is the only enzyme that can cleave the triple bond in N2, making nitrogen avaiable for other organisms. It contains a complicated MoFe7S9C(homocitrate) cluster in its active site. Many computational studies with density-functional theory (DFT) of the nitrogenase enzyme have been presented, but they do not show any consensus-they do not even agree where the first four protons should be
Objectives: Iron deficiency anemia in childhood is a serious public health problem worldwide. Reticulocyte hemoglobin content (Ret-He) is a novel biomarker of iron deficiency adopted for adults but there is a lack of reference intervals for Ret-He in infants. The aim of this study was to provide data from healthy infants. Methods: Swedish infants (n = 456), born at term after normal pregnancies we
With the arrival of heterogeneous manycores comprising various features to support task, data and instruction-level parallelism, developing applications that take full advantage of the hardware parallel features has become a major challenge. In this paper, we present an extension to our CAL compilation framework (CAL2Many) that supports data parallelism in the CAL Actor Language. Our compilation f
Nonlinear Model Predictive Control (NMPC) is a control strategy based on repeatedly solving an optimal control problem. In this paper we present a new MPC framework for the JModelica.org platform, developed specifically for use in NMPC schemes. The new framework utilizes the fact that the optimal control problem to be solved does not change between solutions, thus decreasing the computation time n
Lipids have been implicated in beta-cell stimulus-secretion coupling. In such a role, lipases in beta-cells would be required to generate lipid coupling factors. We have shown previously that glucose stimulates lipolysis in rodent islets. In addition, lipolysis and diacylglycerol lipase activity in islets are abolished by orlistat, an irreversible lipase inhibitor with a broad specificity for subs
Numerous applications of membrane processes are feasible in pulp mills. The challenges inherent in these applications vary. High pH and high temperature call for ceramic membranes when treating spent pulping liquors, whereas low-cost membranes are needed when treating dilute process streams in mechanical pulp mills. Ultrafiltration has been used to recover lignosulphonate in sulphite pulp mills fo
The marine environment harbors a large proportion of the total biodiversity on this planet, including the majority of the earths’ different phyla and classes. Studying the genomes of marine organisms can bring interesting insights into genome evolution. Today, almost all marine organismal groups are understudied with respect to their genomes. One potential reason is that extraction of high-quality
Objectives: To evaluate the feasibility in a pilot study of in vitro endothelialisation of PTFE grafts used as interposition arteriovenous fistulas in uraemic patients. Methods: Autologous saphenous vein endothelial cells were harvested and cultured on PTFE grafts in seven patients undergoing maintenance haemodialysis. The patients had several previous failures of vascular access sites. The patien
Introduction Anal fistula is an abnormal tract with an external and internal opening that cause leakage, discomfort, and occasionally pain. Surgery is standard treatment, but recurrence and anal incontinence is common. The objective of the study was to analyze resource use, costs and sick leave for newly diagnosed patients with anal fistula in Sweden. Methods The study was based on register data f
In this work, laser-based diagnostic techniques were developed and applied to investigate soot formation in small-scale laboratory burners as well as in practical combustion devices. Quantitative 2D laser-induced incandescence (LII) measurements often use a cylindrical lens to shape the beam and illuminate the planar region of interest. The varying laser fluence and sheet width in the imaged flame
