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Background and aims Diet and smoking expose the general population to cadmium (Cd), which is a toxic metal that accumulates in the arterial wall. In experimental studies, Cd causes reductions in proliferation of smooth muscle cells and cellular synthesis of procollagen. The aim of this study was to examine whether blood Cd levels, a valid measure of Cd exposure, are associated with increased risk
Several large-scale genome-wide association studies have identified single-nucleotide polymorphisms in the genomic region of A Disintegrin And Metalloproteinase with ThromboSpondin type 1 repeats (ADAMTS)-7 and associations to coronary artery disease. Experimental studies have provided evidence for a functional role of ADAMTS-7 in both injury-induced vascular neointima formation and development of
Background: Growth hormone (GH) has been linked to cardiovascular disease but the exact mechanism of this association is still unclear. We here test if the fasting levels of GH are cross-sectionally associated with carotid intima media thickness (IMT) and whether treatment with fluvastatin affects the fasting level of GH. Methods: We examined the association between GH and IMT in 4425 individuals
International organisations (IOs) play increasingly important roles in world politics. As states face more complex challenges they have joined together in IOs to solve their common problems. Yet once an IO has been created it may take on a life of its own, and it becomes difficult for its state founders to control what it does. Permanent secretariats populated by experts are one of the most import
Parvalbumin- (PV-) containing basket cells constitute perisomatic GABAergic inhibitory interneurons innervating principal cells at perisomatic area, a strategic location that allows them to efficiently control the output and synchronize oscillatory activity at gamma frequency (30–90 Hz) oscillations. This oscillatory activity can convert into higher frequency epileptiform activity, and therefore c
Previous research has established that when engaged in episodic memory retrieval, people frequently look at locations associated with the sought-after memory trace, even if those locations no longer contain any information. While it has been further demonstrated that gaze positions showing compatibility between encoding and retrieval increase the likelihood of successful remembering (Johansson &amPrevious research has established that when engaged in episodic memory retrieval, people frequently look at locations associated with the sought-after memory trace, even if those locations no longer contain any information. While it has been further demonstrated that gaze positions showing compatibility between encoding and retrieval increase the likelihood of successful remembering (Johansson &am
Background Whole-genome sequencing (WGS) of heart transplant recipient- and donor-derived cardiac biopsies may facilitate organ matching, graft failure prediction, and immunotolerance research. The objective of this study was to determine the feasibility of WGS based on formalin-fixed paraffin-embedded endomyocardial biopsies. Methods and results The study included serial donor- and recipient samp
Clinical studies of Parkinson’s disease (PD) using a dopamine cell replacment strategy have been tried for more than 30 years. The outcomes following transplantation of human fetal ventral mesencephalic tissue (hfVM) have been variable, with some patients coming off their anti-PD treatment for many years and others not responding and/or developing significant side effects, including graft-induced
Objective: Vascular endothelial growth factor D (VEGF-D) has important functions in lymphangiogenesis and angiogenesis. High plasma levels of VEGF-D have been associated with incidence of heart failure. The association of VEGF-D with atrial fibrillation (AF) and stroke is unclear and we hypothesised that VEGF-D could also be associated with incidence of AF and ischaemic stroke. Methods: VEGF-D was
To identify novel coding association signals and facilitate characterization of mechanisms influencing glycemic traits and type 2 diabetes risk, we analyzed 109,215 variants derived from exome array genotyping together with an additional 390,225 variants from exome sequence in up to 39,339 normoglycemic individuals from five ancestry groups. We identified a novel association between the coding var
Sustainable groundwater resources management in arid areas requires early and immediate action to prevent further negative impacts on these resources. The persistent decline in the quantity and quality of groundwater in many countries has been leading to severe challenges in the present and future. In this research, the factors affecting groundwater salinization in a coastal aquifer were evaluated
Voltage-gated Ca2+ (CaV) channels trigger glucose-induced insulin secretion in pancreatic beta-cell and their dysfunction increases diabetes risk. These heteromeric complexes include the main subunit alpha1, and the accessory ones, including subunit gamma that remains unexplored. Here, we demonstrate that CaV gamma subunit 4 (CaVγ4) is downregulated in islets from human donors with diabetes, diabe
High-profile bribery scandals that involve powerful people and large sums of money are often the object of general indignation and legal action. When it comes to bribery of the everyday kind, however, it is far less obvious which gifts should be seen as bribes, be it in a moral or legal sense. Legal cases of this kind almost always include voices that strive to refute accusations of bribery. This
Analytical solutions to 2D depth-averaged (external mode) and fully 3D (internal mode) periodic flows for numerical model testing are presented in this paper. These solutions take into account the effects of the bottom friction, the horizontal turbulent viscosity, and the vertical turbulent viscosity for the case of 3D flow. The key linkage for the modes is the relationship between the bottom fric
Uppsatsmall 1 Disaster risk management and climate change adaptation in urban contexts: Integration and challenges Claudia Marina Rivera Escorcia DOCTORAL DISSERTATION by due permission of the Faculty of Engineering, Lund University, Sweden. To be defended at lecture hall A:C, A-huset, Lund Friday, 11th March 2016, at 13.15 hr. 2 Organization LUND UNIVERSITY Division of Risk Management and Societa
https://www.cencip.lu.se/sites/cencip.lu.se/files/thesis_claudia_rivera.pdf - 2026-07-10
2001 Opportunities and threats to local sustainable development: Introducing ecotourism to Venado Island, Costa Rica Prepared by Björn G. Beeler 4304 Amoroso Place Davis, Ca 95616 U.S.A. (530) 758-1447 BjBeeler@hotmail.com SUBMITTED TO THE LUND UNIVERSITY'S INTERNATIONAL MASTER'S PROGRAMME IN ENVIRONMENTAL SCIENCES 1999/2000 December 2000 Advisor Professor Eric Clark Department of Social and Econo
https://www.lumes.lu.se/sites/lumes.lu.se/files/beeler_bjorn.pdf - 2026-07-10
1 “Can the sunshine be enough? An evaluation of the Greek Photovoltaic Rooftop Program according to sustainability science” A Master Thesis By Zoi Volioti Email: zoivolioti@gmail.com Supervisor: Carl Dalhammar Email: carl.dalhammar@iiiee.lu.se LUMES 2010 2 Acknowledgments This thesis research and writing process came at a period of my life where everything changed. It was one of the most difficult
https://www.lumes.lu.se/sites/lumes.lu.se/files/volioti_zoi_thesis_2010.pdf - 2026-07-10
