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PTSD symptomatology is known to be associated with executive dysfunction. Inhibitory control is a core component of executive functioning, and inhibitory skills are essential both for adequate functioning in everyday life and important in situations following trauma. The aim of the present study was to examine the relationship between trauma exposure, inhibitory control and PTSD symptomatology in
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This paper explores the potential of corpus data to account for language users’ mental representations of a high-frequency item that is prone to phonetic reduction. We present an analysis of the realisations of semi-modal have to in spoken American English, which is a candidate for to-contraction (compare wanna and gotta) but has no clearly established contracted form. The study therefore focusses
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This article draws on usability evaluations of a behavioural change intervention delivered as a web-based course. Special attention was given to usability as the course is directed at older adults aged 70 and above. Experiences from the usability evaluations in a lab environment and the real world, followed by stepwise refinements, can serve as examples of what must be considered in developing cou
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Background: The protein C anticoagulant system plays a key role in maintaining the hemostatic balance. Although several studies have identified thrombomodulin gene (THBD) variants among venous thromboembolism (VTE) patients, the role of THBD in relation to VTE in humans remains to be clarified. Objectives: This study aimed to determine the thrombotic risk of rare and common THBD variants in a larg
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Background: Tissue factor is the main initiator of blood coagulation, and tissue factor pathway inhibitor (TFPI) is the primary inhibitor of the initiation of blood coagulation. The genetic variation of TFPI and the relation to venous thromboembolism (VTE), that is, venous thrombosis and pulmonary embolism, remains to be clarified. This exome sequencing study aimed to determine the molecular epide
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AIMS: Inflammation is a key factor in atherosclerosis. The transcription factor interferon regulatory factor-5 (IRF5) drives macrophages towards a pro-inflammatory state. We investigated the role of IRF5 in human atherosclerosis and plaque stability.METHODS AND RESULTS: Bulk RNA sequencing from the Carotid Plaque Imaging Project biobank were used to mine associations between major macrophage assoc
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6G systems, such as Large Intelligent Surfaces, will require distributed, complex, and coordinated decisions throughout a very heterogeneous and cell free infrastructure. This will require a fundamentally redesigned software infrastructure accompanied by massively distributed and heterogeneous computing resources, vastly different from current wireless networks.To address these challenges, in this6G systems, such as Large Intelligent Surfaces, will require distributed, complex, and coordinated decisions throughout a very heterogeneous and cell free infrastructure. This will require a fundamentally redesigned software infrastructure accompanied by massively distributed and heterogeneous computing resources, vastly different from current wireless networks.To address these challenges, in this
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Background: Vasopressin concentration is typically higher at night, during stress, and in males, but readily lowered by water intake. Vasopressin is also a causal candidate for cardiometabolic disease, which shows seasonal variation. Objective: To study whether vasopressin concentration varies by season in a temperate climate. Methods: The vasopressin surrogate marker copeptin was analyzed in fast
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BACKGROUND: Obesity is strongly associated with the development of cardiovascular disease (CVD). However, the heterogenous nature of obesity in CVD-risk is still poorly understood. We aimed to explore novel CVD biomarkers and their possible association with presumed unhealthy obesity, defined as hospitalized subjects with obesity (HO).METHODS: Ninety-two proteins associated with CVD were analyzed
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Gestational diabetes mellitus (GDM) is associated with increased risk of pregnancy complications and adverse perinatal outcomes. GDM often reoccurs and is associated with increased risk of subsequent diagnosis of type 2 diabetes (T2D). To improve our understanding of the aetiological factors and molecular processes driving the occurrence of GDM, including the extent to which these overlap with T2D
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Background: Severe alpha-1-antitrypsin deficiency (AATD), phenotype PiZZ, was associated with venous thromboembolism (VTE) in a case-control study. Objectives: This study aimed to determine the genetic variation in the SERPINA1 gene and a possible thrombotic risk of these variants in a population-based cohort study. Patients/Methods: The coding sequence of SERPINA1 was analyzed for the Z (rs289294
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Can climate signals help investors make sharper moves in volatile commodity markets? This study explores how weather-related risk, specifically the El Niño-Southern Oscillation (ENSO), can be used to improve portfolio performance. We incorporate the Oceanic Niño Index (ONI) into a Random Forest forecasting model to capture the complex, non-linear effects of climate anomalies on commodity returns -
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In this thesis we employ the method of eigenfamilies in order to construct explicit examples of complete minimal submanifolds in the classical non-compact Riemannian symmetric spaces $$\SLR n/\SO(n),\ \Sp(n,\R)/\UU(n),\ \SO^*(2n)/\UU(n),\ \SU^*(2n)/\Sp(n).$$ In each case, we produce a multidimensional parametrized family of complete minimal submanifolds of codimension two. The results form a conti
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This study examines how different age compositions within a football squad affect a club’s sporting performance and financial development over time. Five squad versions with systematically varied proportions of young and older players were simulated in the game Football Manager 2024™. Each version was followed over ten seasons, resulting in a total of 25 simulations (five repetitions per version).
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The paper reviewed a collection of studies from 2015-2025 in Sweden on municipal organizational change, with the aim of discussing challenges and benefits during modern change processes and connecting it to previously existing theories. The results showed that there is some conflict between different governance models (mainly NPM and TBG), that TBG can be implemented differently in different munic
