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Type 2 diabetes has become a leading health problem throughout the world. The escalating epidemic of type 2 diabetes is believed to result from a collision between inherent biological susceptibilities (genotypes) and a shift toward dietary habits and lifestyle that promote obesity over the past several decades; the transition from “traditional” to modern “obesogenic” lifestyles is characterized by
Importance: The role of ω-3 polyunsaturated fatty acids for primary prevention of coronary heart disease (CHD) remains controversial. Most prior longitudinal studies evaluated self-reported consumption rather than biomarkers. Objective: To evaluate biomarkers of seafood-derived eicosapentaenoic acid (EPA; 20:5 ω-3), docosapentaenoic acid (DPA; 22:5 ω-3), and docosahexaenoic acid (DHA; 22:6 ω-3) an
Tissue transglutaminase (tTG) and microbial transglutaminase (mTG) cross-link gliadins to form complexes that expose immunogenic neo-epitopes to produce tTG and mTG-neo-epitope antibodies. The aim of this study was to test the diagnostic performance of antibodies against non-complexed and complexed forms of transglutaminases, to correlate their activities to the intestinal damage and to explore ag
Aims: Brisk walking and a greater muscle strength have been associated with a longer life; whether these associations are influenced by other lifestyle behaviours, however, is less well known. Methods: Information on usual walking pace (self-defined as slow, steady/average, or brisk), dynamometer-assessed handgrip strength, lifestyle behaviours (physical activity, TV viewing, diet, alcohol intake,
Objective: Higher gluten intake, frequent gastrointestinal infections and adenovirus, enterovirus, rotavirus and reovirus have been proposed as environmental triggers for coeliac disease. However, it is not known whether an interaction exists between the ingested gluten amount and viral exposures in the development of coeliac disease. This study investigated whether distinct viral exposures alone
Coronary artery disease (CAD) is more frequent among individuals with dysglycemia. Preventive interventions for diabetes can improve cardiometabolic risk factors (CRFs), but it is unclear whether the benefits on CRFs are similar for individuals at different genetic risk for CAD. We built a 201-variant polygenic risk score (PRS) for CAD and tested for interaction with diabetes prevention strategies
Previous studies report that dental caries is partially heritable, but there is uncertainty in the magnitude of genetic effects and little understanding of how genetic factors might influence caries progression or caries subtypes. This study aimed to estimate the relative importance of genetic and environmental factors in the etiology of different caries outcomes using a twin-based design. Analysi
Aims/hypothesis: It is well established that physical activity, abdominal ectopic fat and glycaemic regulation are related but the underlying structure of these relationships is unclear. The previously proposed twin-cycle hypothesis (TC) provides a mechanistic basis for impairment in glycaemic control through the interactions of substrate availability, substrate metabolism and abdominal ectopic fa
Vehicles equipped with sensors can participate inmobile crowdsourcing applications. Vehicular Ad Hoc Networks(VANETs) based on Dedicated Short Range Communication(DSRC) are used to carry sensing data. However, multi-hoptransmissions for gathering data to Road Side Units (RSUs) inVANETs suffer from low data rate and long end-to-end delay,which can hardly meet the QoS requirements of delay-sensitive
Title: Returns on Assets and Returns on Stocks: Based on Swedish Market. Authors:Tatiana Studyanikova and Eirini Sarantopoulou. Advisor:Hossein Asgharian. Key Words: Returns on assets (ROA), returns on stocks (ROS), variation, principal component analysis, firm-specific level. Purpose: Examine whether common factors of returns on stocks and returns on assets explain most of the variation in return
This study investigates the effects and policy lessons from the surge of capital inflows that the Baltic countries experienced during the period 2004-2008. We discuss the main risks and policy challenges involved with such an episode and assess what scope there was for policy makers to face these challenges. We also devote some attention to the area of measuring exchange rate pressure by applicati
Presently the telecom industry is going through a massive shift in technology. In the business to business environment regarding delivery and service of fixed telephony, the traditional circuit-switched PBX (private branch exchange) technology is successively replaced by a new Ip-based (Internet protocol) PBX technology. The new way of switching voice-calls doesn't demand a separate infrastruc
Postprandial insulinaemia, triglyceridaemia and measures of inflammation are thought to be more closely associated with cardiovascular risk than fasting measures. Although hypertension is associated with altered fasting metabolism, it is unknown as to what extent postprandial lipaemic and inflammatory metabolic responses differ between hypertensive and normotensive individuals. Linear models adjus
Background: The prevalence of celiac disease in the general population is mainly unknown in most of sub-Saharan African countries. The aim of this study was to determine the incidence of celiac disease autoimmunity (CDA) and its associations with latent Mycobacterium tuberculosis (LMTB) and Helicobacter pylori (HP) infections in Ethiopian children aged 4 years in an HLA genotyped cohort study. Met
Due to the changing landscapes of higher education, a large body of research has studied how scholars make sense of academic identities and careers. Yet, little is known about how academics actually ‘work’ on their identities to navigate normative demands and complex career structures. This paper explores how scholars negotiate career scripts trough identity work. Drawing upon 35 interviews with eDue to the changing landscapes of higher education, a large body of research has studied how scholars make sense of academic identities and careers. Yet, little is known about how academics actually ‘work’ on their identities to navigate normative demands and complex career structures. This paper explores how scholars negotiate career scripts trough identity work. Drawing upon 35 interviews with e
Precision nutrition is an emerging concept that aims to develop nutrition recommendations tailored to different people's circumstances and biological characteristics. Responses to dietary change and the resulting health outcomes from consuming different diets may vary significantly between people based on interactions between their genetic backgrounds, physiology, microbiome, underlying health sta
