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Bleeding complications after cardiac arrest and targeted temperature management, a post hoc study of the targeted temperature management trial

Target Temperature Management (TTM) is standard care following out of hospital cardiac arrest (OHCA). The aim of the study was to evaluate if treatment temperature (33°C or 36°C) or other predefined variables were associated with the occurrence of bleeding in the TTM study. This study is a predefined, post hoc analysis of the TTM trial, a multinational randomized controlled trial comparing treatme

When implementation falters: the challenge of having peripheral issues stick in organisations

Purpose – The purpose of this paper is to study a class of issues that in spite of recognised needs and explicit managerial demands have proven hard to have “stick” in organisations (information security is used as an example). It offers a theory-driven rationale why superficially different issue areas can indeed be considered as instances of the identified class, and builds on complexity leadershPurposeThe purpose of this paper is to study a class of issues that in spite of recognised needs and explicit managerial demands have proven hard to have “stick” in organisations (information security is used as an example). It offers a theory-driven rationale why superficially different issue areas can indeed be considered as instances of the identified class, and builds on complexity leadership

Gene expression profiling of first trimester placentas from pregnancies at high risk of developing preeclampsia

INTRODUCTION: Preeclampsia (PE) is an important cause of fetal and maternal morbidity and mortality. It is considered a two-stage disease, the first stage characterized by a defect placentation and the second stage by maternal manifestations. Details of the patho-physiology behind the transition from stage one to stage two remain unclear.OBJECTIVE: Was to study first trimester placental gene expre

Deficiencies in healthcare prior to suicide and actions to deal with them : A retrospective study of investigations after suicide in Swedish healthcare

Objectives The overall aim of this study was to aggregate the conclusions of all investigations conducted after suicides reported to the supervisory authority in Sweden in 2015, and to identify deficiencies in healthcare found in these investigations; the actions proposed to deal with the deficiencies; the level of the organisational hierarchy (micro-meso-macro) in which the deficiencies and actio

Managing risks in supply chains - an article review and Appendix

Background: A number of trends during the last decade, like globalisation, outsourcing, single sourcing, leanness and agility, have made the supply chain more vulnerable and “supply chain risk management” has become a research area of its own. Objective: To characterize the existing scientific knowledge and scientific knowledge creation within supply chain risk management as it is presented in the

Coarse-Grained Models of Ionic Solutions

Room-temperature ionic liquids (RTILs) are compounds composed entirely of ions, which are liquid at temperatures below 100 degrees Celsius. Their high ionic strength and strong coupling make them useful for a number of applications, e.g. as electrolytes in supercapacitors. These properties also make them interesting subjects for theoretical research, as the canonical theories of the electrical dou

reqT.org – Towards a Semi-Formal, Open and Scalable Requirements Modeling Tool

[Context and motivation] This research preview presents ongoing work on a free software requirements modeling tool called reqT that is developed in an educational context. [Question/problem] The work aims to engage computer science students in Requirements Engineering (RE) through a tool that captures essential RE concepts in executable code. [Principal ideas] Requirements are modeled using an int

The Mobile Oracle – an on Demand Wizard of Oz Tool

This paper describes a novel tool for eliciting user requirements early in the design process of mobile applications. The “Mobile Oracle”, as we have called it, is intended to help developers and designers obtain a better understanding of what the user wants at different points in space and time. It is an extension of a lo-fi version of the well-established Wizard of Oz technique, but it also adds

The K-Cl cotransporter in the lobster stretch receptor neurone-a kinetic analysis.

Experiments were performed to define quantitatively the substrate (K(+) and Cl(-)) dependence of the transport function (production of equally large and oppositely directed K(+)and Cl(-) flows/currents) of an earlier (Theander et al., 1999) identified electroneutral K-Cl cotransporter in the slowly adapting stretch receptor neurone of the European lobster. The experiments were based on microelectr

Faculty Development for Educational Leadership

The chapter describes five examples of dedicated faculty development trajectories for educational leadership in research-intensive universities, focusing on their nature and effects. After discussing and elaborating on the concept of ‘educational leadership’, the chapter portrays and compares professional development trajectories for educational leadership in five research-intensive universities:

An Empirical Investigation of the Right to Explanation Under GDPR in Insurance

The GDPR aims at strengthening the rights of data subjects and to build trust in the digital single market. This is manifested by the introduction of a new principle of transparency. It is, however, not obvious what this means in practice: What kind of answers can be expected to GDPR requests citing the right to “meaningful information”? This is the question addressed in this article. Seven insuraThe GDPR aims at strengthening the rights of data subjects and to build trust in the digital single market. This is manifested by the introduction of a new principle of transparency. It is, however, not obvious what this means in practice: What kind of answers can be expected to GDPR requests citing the right to “meaningful information”? This is the question addressed in this article. Seven insura

Palliative care during the final week of life of older people in nursing homes : A register-based study

Objective:: Our aim was to explore the presence of symptoms, symptom relief, and other key aspects of palliative care during the final week of life among older people residing in nursing homes. Method:: Our study employed data from the Swedish Palliative Care Register on all registered individuals aged 60 and older who had died in nursing homes during the years 2011 and 2012. Variables pertaining

Radiopaque dyes allow vessel imaging in lung tissue using laboratory phase contrast micro-CT

Phase contrast micro-CT is a powerful technique allowing imaging of soft tissue at synchrotrons or using lab- oratory sources. The use of contrast agents is a useful approach when imaging vascular structures. However, common x-ray contrast agents typically rely on heavy metals to increase absorption, which may affect the phase contrast and cause artifacts in the reconstructed volumes. Thus, utiliz

Clinical Characteristics and Self-Harm in Forensic Psychiatric Patients

Self-harm, comprising non-suicidal self-injury, and suicide attempts, is a serious and potentially life-threatening behavior that has been associated with poor life quality and an increased risk of suicide. In forensic populations, increased rates of self-harm have been reported, and suicide is one of the leading causes of death. Aside from associations between self-harm and mental disorders, know

Eliciting Anti-Tumor Immunity by Reprogramming Cancer Cells to Type 1 Conventional Dendritic Cells

IntroductionAn important hallmark of cancer is escaping the immune system. Despite advances in immunotherapy, only a subset of patients experiences clinical benefits. It was shown that adoptive T cell or checkpoint inhibition therapy rely on the presence of conventional dendritic cells type 1 (cDC1). cDC1 excel in recruiting and priming protective CD8+ T cells through cross-presentation. However,

"Tid är liv – därför bör Skåne införa sms-livräddning nu"

Varje minuts fördröjning av hjärt-lungräddning minskar chansen till överlevnad med 10 procent, skriver åtta forskare vid Centrum för hjärtstopp vid Lunds universitet.Eight researchers at the Lund University Center for Cardiac Arrest write that every minute of delay in cardiopulmonary resuscitation reduces the chance of survival by 10 percent.

Good intentions gone awry: investigating a strategically oriented MLD program

Purpose Complex organizations increasingly rely on middle managers as strategic linking-pins between the top and bottom levels of the organization. Using social identity theory and commitment theory as the foundation, this study evaluates a management and leadership development program (MLDP) intended to engage middle managers as strategy creators and implementers. We also evaluate the cascading ePurpose Complex organizations increasingly rely on middle managers as strategic linking-pins between the top and bottom levels of the organization. Using social identity theory and commitment theory as the foundation, this study evaluates a management and leadership development program (MLDP) intended to engage middle managers as strategy creators and implementers. We also evaluate the cascading e

Spatial Planning and Sociology of Law: Sustainable development issues in constructing infrastructure for the third generation mobile telephone system in Sweden

The infrastructure for the third generation of mobile telephony, UMTS, is under construction in Sweden. Within three years four operators were to build competing systems to cover 99,98 % of the population. The case of the 3G infrastructure illustrates how sustainability issues are handled in planning and environmental management, with conflicting goals between institutional levels and contradict