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Background & Aims: In 2014, the burden of hepatitis C virus (HCV) in Sweden was evaluated, to establish a baseline and inform public health interventions. Considering the changing landscape of HCV treatment, prevention, and care, and in light of the COVID-19 pandemic, this analysis seeks to evaluate Sweden's progress towards the World Health Organization (WHO) elimination targets and identify
The transition from fossil jet fuel to biojet fuel is an important step towards reducing greenhouse gas (GHG) emissions from aviation. To enable such a fuel shift, the Swedish Government introduced a GHG emission reduction mandate of 27% by 2030 for aviation fuel sold in Sweden, forcing fuel suppliers to blend in biojet fuel in fossil jet fuel. A similar policy instrument is being discussed within
Introduction: Our objective was determining the optimal combinations of cerebrospinal fluid (CSF) biomarkers for predicting disease progression in Alzheimer's disease (AD) and other neurodegenerative diseases. Methods: We included 1,983 participants from three different cohorts with longitudinal cognitive and clinical data, and baseline CSF levels of Aβ42, Aβ40, phosphorylated tau at threonine-181
Introduction: Haemophilia A care has changed with the introduction of emicizumab. Experience on the youngest children is still scarce and clinical practice varies between haemophilia treatment centres. Aim: We aimed to assess the current clinical practice on emicizumab prophylaxis within PedNet, a collaborative research platform for paediatricians treating children with haemophilia. Methods: An el
Peatlands have become a silver bullet in climate mitigation policy globally. Restoring and rewetting agricultural peatlands is key for meeting reduction targets within the agricultural sector. But unlike other sectors, change rests on the decisions of individual farmers. In Denmark, a political aim towards restoring 100.000 hectares of agricultural peatlands by 2030 is challenged by uncertainty, d
Cities around the world are facing a multitude of urban challenges that demand that they change the way they plan and think about their city, with one of the ways of approaching sustainability being the Smart city. A core feature of the Smart city is the idea of collecting large quantities of data on the city, big data, which is then used in various city solutions. In the wake of this, several que
Climate change is intensifying short-duration rainfall extremes, increasing urban pluvial flood risk across Swedish municipalities. This study develops a novel spatial statistical framework for basement flood risk assessment using Log-Gaussian Cox Process (LGCP) models on metric graphs, applied to 17 years of flood records from Trelleborg, southern Sweden.Unlike conventional approaches that treat
Industrial activities, mining and waste management have resulted in extensive contamination of soil, surface water and groundwater all over the world. Around the world, there are different methods used to classify contaminated sites into different risk classes. In Sweden, the method for the inventory of contaminated sites (MIFO) is used. Naturvårdsverket developed it in 1999. MIFO is divided into
Quantum entanglement is a fundamental resource for various quantum information applications including quantum computing, cryptography, and teleportation. However, detecting entanglement in practice can be challenging due to noisy measurements and limited control over the systems being studied. Steering, which is a distinct nonlocal property between entanglement and bell nonlocality (the strongest
Chronic respiratory diseases (CRDs) are a group of incurable conditions, among which the most common, such as COPD and asthma, have significant negative impacts on patients’ mental health and economic productivity. Understanding of the causes and affected populations of CRDs is continuously evolving, with air pollution now recognized as an important etiological factor alongside smoking, receiving
The World Heritage Site Venice and its Lagoon faces major challenges to its conservation, mainly those of mass tourism and climate change. This thesis examines how Venice is represented and managed as a World Heritage Site in official reports by Unesco and Italy, with a particular focus on conservation, tourism and sustainability. The study is conducted through a qualitative content analysis of Un
The consequences of climate change include an increased risk of landslides, erosion and flooding of buildings in cities. Swedish municipalities have a planning monopoly, which means they have autonomy over urban planning and consequently a responsibility to climate-adapt their cities. It is not enough to focus solely on reducing emissions, climate adaptation measures must also be implemented. To m
Agricultural intensification is a major driver of biodiversity loss, which highlights the need for effective policy instruments that promote sustainable farming. Therefore, the EUs common agricultural policy (CAP) plays a major role, especially the voluntary eco-schemes that are designed to incentivize such practices. However, the effectiveness of these policies depends both on farmer participatio
Objectives To identify and describe frameworks for systematically identifying research gaps from evidence syntheses, framing research needs, and establishing priorities, with emphasis on their use of GRADE (Grading of Recommendations Assessment, Development and Evaluation) certainty of evidence (CoE) domains and evidence-to-decision (EtD) criteria. Study Design and Setting We conducted a scoping r
Growing concerns around resource depletion and climate change has made freshwater scarcity an increasingly urgent issue for cities around the world. In Cape Town, this became especially visible during the 2018 Day Zero crisis, when the City of Cape Town faced the possibility of its municipal water supply systems reaching a critical failure point. This thesis examines how freshwater scarcity in Cap
