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BACKGROUND: Cardiovascular calcification is a significant predictor and contributor to cardiovascular diseases. Vascular smooth muscle cell (SMC)-derived extracellular vesicles (EVs) play a crucial role in microcalcification formation. EVs can originate from the endosomal system, and PIKFYVE (1-phosphatidylinositol 3-phosphate 5-kinase), a lipid kinase, plays a key role in endomembrane maturation.

Understanding greenhouse gas fluxes in semi-arid ecosystems is critical for improving our understanding of biogeochemical cycles, particularly in underrepresented regions like the African Sahel. In these landscapes, greenhouse gas exchange arises from ground, trees, and water ponds, and is further shaped by environmental conditions and grazing. The carbon dioxide, methane, and nitrous oxide fluxes

Objectives To examine the associations between socioeconomic position (SEP) and the incidence of serious hand infections—pyogenic flexor tenosynovitis (PFT) and septic arthritis (SA)—as well as risks of opioid overuse following diagnosis using nation-level data. Design In a registry-based nationwide retrospective cohort study, (1) associations between SEP and incidence of PFT/SA; (2) SEP and infec

Purpose Gangliogliomas are highly epileptogenic tumors that are common in epilepsy surgery. The main aim of this study was to investigate whether the outcome of Anti-seizure medication (ASM) withdrawal differed between patients undergoing ganglioglioma surgery in an epilepsy surgery program compared with those who underwent surgery in other surgical programs. We also investigated which factors inf

Optical genome mapping (OGM) enables high-resolution detection of structural variants (SVs) and copy number aberrations (CNAs) using ultralong DNA molecules and minimal bioinformatics processing. Its diagnostic utility in solid tumors remains underexplored. Whole-genome sequencing (WGS) offers comprehensive variant detection but is resource intensive. This study presents a technical benchmarking o

Performance featuring spherical amplification.Wiener FestwochenORF RadioKulturhaus, Wien (AT)Klangforum Wien & Irene Delgado-Jiménez09/06/2024From the program “Academy Second Modernism: No Excuses Anymore II”:Ivičević, Mirela (*1980, HR) – Case Black (for ensemble and electronics) [2016]

Litter decomposition is a source of gaseous products, including volatile organic compounds (VOCs) to the atmosphere. The quantity and the chemical composition of the VOC blends released from litter vary between plant species and depend on environmental factors and litter microbial communities. Here, we assessed VOC release from decomposing litter in a 3-year incubation conducted in a climate manip

Background There is a lack of contemporary data describing patients with left ventricular (LV) systolic dysfunction post myocardial infarction (MI) in terms of symptom burden and secondary prevention measures. The aim of this study was to describe patients with various degrees of LV systolic dysfunction after a first MI, their symptom burden, quality of life and adherence to recommended secondary

Visual assessment of medial temporal lobe atrophy (MTA) in the clinical workup of cognitive impairment is traditionally corrected for age since MTA increases with age. In addition, common pathologies in the elderly such as amyloid, tau, alpha-synuclein and TDP-43 accumulation as well as white matter hyperintensities representing small vessel disease may affect the association between MTA and age.

Performance featuring spherical amplification.Festival ‘Was die Linden flüstern’Saal Dreilinden, Luzern (CH)Ensemble für neue Musik Zürich30/05/2024Program:Haas, Lorenz (*1968, CH) – Nichts Schöneres (a Schumann song recital in fourteen scenes for seven instruments and voice) [2024] WP

Controlled and sequence-selective DNA cleavage plays a crucial role in biomolecular engineering and nucleic acid technologies. Here, we report the development of cerium-coordinated catalytic hydrogel nanoparticles (Ce-CHNP) that exhibit single-strand-selective nuclease activity. Ce-CHNP was synthesized via a one-step polymerization process in which Ce(IV) coordinated with N-hydroxymethyl acrylamid

Performance featuring spherical amplification.Cantiere Internazionale d’ArteFortezza Medicea, Chiostro, Montepulciano (IT)Solo – Opificio Sonoro Short III25/07/2024Program:Tedde, Maurizio (*1996, IT) – Januvia (for e-guitar and electronics) [2024] WP

Performance featuring spherical amplification.Foresty FestivalTeatro San Martino, Montaldeo (IT)Solo02/08/2024Program:Billone, Pierluigi (*1960, IT) – Sgorgo Y (for e-guitar) [2012]

Performance featuring spherical amplification.Festival Orizzonti Autumn Edition IAuditorium S. Cecilia, Perugia (IT)Opificio Sonoro21/11/2024From the Program “The Adventures of Foreign Bodies #1 – Venus Station”:Tedde, Maurizio (*1996, IT) – Januvia (for e-guitar and electronics) [2024]

Performance featuring spherical amplification.#3 Cantiones – Hommage an Klaus Huber 100. GeburtstagGrossmünster, Zürich (CH)Collegium Novum Zürich30/11/2024From the Program:Pagh-Paan, Younghi (*1945, KR) – SOWON/Wunsch (for soprano and 10 instruments) [1996]Huber, Klaus (1924-2017, CH) – Cantiones de Circulo gyrante (spatialized music for five soloists, choir and three instrumental groups) [1984]

One of the most important travelers of the 18th century was Jakob JonasBjörnståhl. From a young age, he aspired to reach prominence in academiccircles. Greek, Latin, and various Middle Eastern languages were part ofhis studies from the outset, and he distinguished himself by his enthusiasm,thirst for knowledge, and ability to quickly master diverse subjects, alongwith his encyclopedic education. HOne of the most important travelers of the 18th century was Jakob Jonas Björnståhl. From a young age, he aspired to reach prominence in academic circles. Greek, Latin, and various Middle Eastern languages were part of his studies from the outset, and he distinguished himself by his enthusiasm, thirst for knowledge, and ability to quickly master diverse subjects, along with his encyclopedic educati

We investigate the influence of AlN buffer thickness on the structural, electrical, and thermal properties of AlGaN/GaN high-electron mobility transistors (HEMTs) grown on semi-insulating SiC substrates by metal-organic chemical vapor deposition. X-ray diffraction and atomic force microscopy reveal that while thin AlN layers (120 nm) exhibit compressive strain and smooth step-flow surfaces, thicke

Action-detected two-dimensional electronic spectroscopy (A-2DES) provides valuable insights into ultrafast dynamics within functional materials and devices by measuring incoherent signals like photocurrent. This work details the implementation and optimization of a pulse-shaper-based A-2DES setup, focusing on methodological strategies crucial for acquiring high-fidelity data. We present a comprehe