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Background: Strong sex disparities have been observed among patients with bladder cancer (BCa). FGFR3 is one of the most frequently mutated genes in bladder cancer, and there are inconsistencies in its frequency in male and female patients. Methods: Here, we conducted a meta-analysis comparing the FGFR3 somatic mutation frequency in men and women among 7351 patients with BCa from 18 cohorts. Resul
OBJECTIVES: Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal disease that is challenging to detect at an early stage. Biomarkers are needed that can detect PDAC early in the course of disease when interventions lead to the best outcomes. We highlight study design and statistical considerations that inform pancreatic cancer early detection biomarker evaluation.METHODS: We describe experim
IntroductionThe implementation of welfare technologies in Swedish eldercare reflects ongoing sociotechnical transitions, which promise to optimise care practices and administrative processes. AimOur study explores how eldercare personnel interpret and ascribe meanings to welfare technologies in their everyday care work.Material and MethodsThe study draws on an empirical dataset comprising 181 phot
Purpose: Child-to-parent violence (CPV) is an increasingly important social issue, with most research concentrated in a few countries, highlighting a need for more research on the subject. In this study, we therefore validate the Swedish version of the Abusive Behavior by Children-Indices (ABC-I), a self-report tool with subscales for verbal aggression, coercive behavior, and physical aggression.
The upstream ends of global supply chains – where raw material extraction or production takes place – are often hotspots for severe sustainability issues such as deforestation, biodiversity loss and human rights violations. Companies are under growing scrutiny from regulators, investors and civil society to ensure upstream-end supply chain sustainability. Yet, companies typically lack visibility b
Serving Aristocracy is the history of social negotiation and mobility in an early modern knowledge community, centred on the aristocratic De la Gardie family and their sphere of manors and estates in seventeenth-century Sweden. Focusing on underprivileged women and men and the knowledge community that shaped their interactions, social negotiations, and mobility, this book documents ordinary people
This thesis consists of three independent research papers. Using both applied econometric methods and theoretical models, they study the functioning of electricity markets, including those for green certificates, and auction markets in the presence of policy and market imperfections. The first paper empirically examines the effect of regulatory uncertainty in quota-based green certificate markets,
We conduct a field experiment studying how financial incentives for achieving specific course grades affect university students, whether effects vary by ability, and whether allowing students to choose their goals improves outcomes. We find that incentives negatively affect performance, particularly among low-ability students assigned high goals. Survey data suggest this negative impact arises fro
As global food systems are currently presenting great challenges to our environment and our health, diverse new (sustainable) foods and possibilities to integrate these into consumers’ everyday diets are extensively studied. Due to industrialized, standardized food production, approaches from disciplines such as sensory science and consumer psychology play an important role in new product developm
När svensk ekonomi var internationellt öppen och konkurrensutsatt närmade vi oss världstoppen i levnadsstandard. Men efterkrigstidens regleringar drev Sverige in i en finansiell istid. USA:s nya styre gör att vissa nu drömmer sig tillbaka till gamla idéer, och då riskerar vi att upprepa ett väl dokumenterat misslyckande, skriver ekonomiprofessor emeritus Lars Jonung.
Introduction: Estimation of the longitudinal relaxation time T1 from the MP2RAGE pulse sequence is based on a monoexponential signal evolution model. However, magnetization transfer caused by the inversion pulse induces a fast relaxation component which appears as a reduction in the efficiency of the inversion. This may explain the underestimation of T1 derived from MP2RAGE. To address this system
The enhancement and protection of coastal ecosystems that sequester carbon for climate change mitigation have developed over the last 15 years, and today are part of climate governance. After an initially challenging start in terms of policy interest, Blue Carbon is now included in some countries’ national inventories, and as such, enters the global sums of emissions and sinks, and becomes relevan
The Intergovernmental Panel on Climate Change needs to do more to include the expertise and voices of women, even as numbers and policies improve.
