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Background: Islet autoantibodies form the foundation for type 1 diabetes (T1D) diagnosis and staging, but heterogeneity exists in T1D development and presentation. We hypothesized that autoantibodies can identify heterogeneity before, at, and after T1D diagnosis, and in response to disease-modifying therapies. Methods: We systematically reviewed PubMed and EMBASE databases (6/14/2022) assessing 10
The landscape of Alzheimer's disease (AD) and related dementias (ADRD) diagnosis is evolving rapidly, driven by advances in disease understanding, biomarker tools, and disease-modifying therapies. Modern diagnostic approaches emphasize biological precision, early detection, and dynamic frameworks that adapt to treatment-induced changes in disease biology. These frameworks enable opportunities for
Do entrepreneurs benefit post their entrepreneurial careers on re-entry into paid employment? An answer to this question provides a career value of engaging in an entrepreneurial career. Results have so far been inconclusive suggesting that we still do not know whether entrepreneurship pays or not. Using job matching as the main theoretical foundation, this study investigates how the returns from
The use of large language models (LLMs) is being explored for a multitude of tasks in software engineering (SE), ranging from code generation to bug report assignment. Although LLMs provide impressive results, they require more time and energy than some other machine learning models. For some tasks, simpler models may be more sustainable than LLMs. In this paper, we construct natural language clas
Accurate global estimates of accumulation-mode particle number concentrations (N100) are essential for understanding aerosol–cloud interactions and their climate effects and for improving Earth system models. However, traditional methods relying on sparse in situ measurements lack comprehensive coverage, and indirect satellite retrievals have limited sensitivity in the relevant size range. To over
Paper om den svensk-judiske historikern Hugo Valentin och dennes texter om förintelsen från tidigt 1940-tal till tidigt 1960-tal.
Artikel om de utrikespolitiska förbindelserna mellan Sverige och USA från ett jubileum 1938 (New Sweden Tercentenary Celebration) till ett annat 1948 (Swedish Pioneer Centennial).
This article explores the regional embeddedness of bioeconomy innovations in Germany, focusing on “flagship” innovation projects that exemplify the challenges and opportunities of systemic changes towards bioeconomies. While bioeconomies have been promoted as solutions to global challenges and opportunities for sustainable regional development, there are ongoing debates about the actual benefits o
The events of September 8, 1978, in Iran, commonly known as ‘Black Friday’, have long been portrayed as a mass killing of peaceful protesters by the Shah’s regime, with widely cited death tolls ranging from several hundred to several thousand. However, this article presents a comprehensive reassessment of the incident at Jaleh Square in Tehran, arguing that the dominant narrative is rooted more in
Acoustofluidic particle manipulation has attracted considerable interest in biomedical applications due to its non-contact and label-free characteristics. However, existing computational models for predicting particle motion in acoustofluidic systems mainly focus on single-particle behavior, often neglecting particle–particle interactions and the impact of particle distribution on the acoustic and
Med tillstand fran Lansstyrelsen i Blekinge Ian genomforde Lunds universitet(LU) och Blekinge museum (ELM) den 17-18 november 2020marinarkeologiska undersokningar pa vraket efter den danske kungen Hanskravel Gribshunden. Vrakplatsen ar belagen omedelbart norr om Stora Ekon iRonneby kommun.Syftet med dykningarna 17-18 november 2020 var att barga tramaterial frantunnor for kompletterande dendrokronoDuring 17-18 November 2020, under a permit from Lansstyrel,en in Blekinge issued toBlekinge Museum (BM), a team coordinated by Lund University (LU) conductedmaritime archaeologicalinvestigations ofthe shipwreck known as Gribshunden. The site is located closeto Stora Ekon, near Saxemara. The dive team visually inspected the wreck site, recovered samples of wooden barrels far dendrochronological ana
Railways are vital for climate mitigation as a low-carbon mode of transport but must also be resilient to climate change impacts. This study explores dynamic adaptation strategies for coastal railway infrastructure in Sweden, focusing on Trelleborg. Stakeholder workshops informed adaptation pathways using a Dynamic Adaptive Pathways Planning Light (DAPP)-light approach, which enhances stakeholder
This ESMO CPG provides key recommendations and algorithms for managing DLBCL, FL, HL, MCL, MZL, PCNSL and PTCL. •It covers epidemiology, diagnosis, staging, risk assessment, treatment of primary and refractory disease and follow-up. •Treatment algorithms for each lymphoma type are provided. •The author group encompasses a multidisciplinary group of experts from different institutions and countries
Background: In Sweden, evidence-based breastfeeding support is provided as part of the 2022–2027 Swedish Food Agency's breastfeeding strategy. Despite 98% of mothers intending to breastfeed, exclusive breastfeeding rates have dropped from 82% in 2014 to 67% in 2022. Child health service nurses offer guidance regarding breastfeeding to women and their partners. The aim of this study was to explore
Objectives: The aim was to explore adolescents’ beliefs and awareness regarding fertility and preconception health, as well as their views and experiences of information about fertility and preconception health directed at their age group. Methods: We performed seven semi-structured focus group interviews among upper secondary school students (n = 47) aged 16–18 years in two Swedish counties. Data
Introduction: Many women and men lack knowledge about fertility, including timing of the fertile window, age-related decline, and lifestyle factors that may impair fertility. The Internet has become an important source of information, but evidence-based information on fertility and reproduction in Swedish on the Internet is limited. The present study aimed to develop and evaluate an evidence-based
