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Background: Residual tumor volume (RTV) and extent of resection (EOR) have previously been shown to affect survival in glioblastoma (GB) patients. Quantitative radiological assessment (QRA) of these factors could potentially affect clinical decision-making in the postoperative period. Purpose: The first aim was to evaluate the reproducibility of different volume estimation methods of RTV and EOR b
The purpose of the paper is to analyse informal collaboration in the public transport sector. Two Swedish case studies, Living lab Uddevalla and Guidelines for Regional BRT are analysed and compared concerning what kind of learning occurred and what lessons regarding informal collaboration to draw from the two cases. For both cases the analysis indicates that individual, single loop learning is th
Symptom-free bacterial colonization of the lower urinary tract in an otherwise healthy individual was long misunderstood. Our current understanding is based on solid research proving that asymptomatic bacteriuria (ABU) is harmless and even protective against symptomatic urinary tract infection episodes. Thus, ABU should not be treated in patients with the exception of before endosurgery and, until
Laminin α2 chain-deficient muscular dystrophy, or LAMA2-CMD, is a very severe disease caused by mutations in the LAMA2 gene. Skeletal muscle is the most affected tissue, with patients presenting symptoms such as hypotonia at birth, joint contractures and progressive muscle wasting. Changes in the central nervous system include white matter abnormalities, delayed motor milestones and compromised ac
Energy intensive industries (EIIs), producing the basic materials and products needed in society, contribute significantly to global emissions of greenhouse gases (GHGs). Motivated by the fear of carbon leakage, climate policy has so far treated the EIIs leniently with e.g. low carbon prices and/or free allocation of emission allowances. This has not resulted in more than marginal emission abatemeEnergy intensive industries (EIIs), producing the basic materials and products needed in society, contributesignificantly to global emissions of greenhouse gases (GHGs). Motivated by the fear of carbon leakage, climatepolicy has so far treated the EIIs leniently with e.g. low carbon prices and/or free allocation of emissionallowances. This has not resulted in more than marginal emission abatement.
We introduce a memory model for robots that can account for many aspects of an inner world, ranging from object permanence, episodic memory, and planning to imagination and reveries. It is modeled after neurophysiological data and includes parts of the cerebral cortex together with models of arousal systems that are relevant for consciousness. The three central components are an identification net
The need to decrease emissions from the transport sector is getting urgent and public transport can play an important role in the transition to low emission fuels. To a large extent, public transport in Europe is provided by regional authorities who controls the traffic to a varying degree, from complete public monopoly to competitive tendering. Therefore, the aim of this paper is to analyse how t
Pain and depressive symptoms are common reasons for adolescents to contact the school nurse. The aim was to describe the prevalence of pain (headache, abdominal pain, and back pain) and depressive symptoms among adolescents and to examine whether there is an association between pain and depressive symptoms. This cross-sectional survey included students (N = 639) in Sweden (median age: 16 years). O
A series of 3-triazole-thiogalactosides and 3,3′-triazole-thiodigalactosides substituted with different five-membered heterocycles at the C-4 triazole position were found to have high selectivity for galectin-1. Initial studies on the 3-triazole-thiogalactosides indicated that five membered heterocycles in general gave increased affinity for galectin-1 and improved selectivity over galectin-3. The
Living labs for sustainability, low carbon and smart cities that have emerged in Europe have different goals and ways of working, they are initiated by various actors, and they form different types of partnerships. There is clearly no uniform definition of living labs. Some scholars and organisations define them as partnerships between sectors (often between public, private and people) where unive
Industrial processes currently account for a significant share (25–35 %) of the world’s total energy demand and related emis- sions. During recent years, the amount of low-carbon electric- ity from renewable energy sources (such as wind and solar) has increased continuously. There is therefore an increasing inter- est in electrification of industrial processes in order to achieve long-term decarboIndustrial processes currently account for a signifcant share (25–35 %) of the world’s total energy demand and related emissions. During recent years, the amount of low-carbon electricity from renewable energy sources (such as wind and solar) has increased continuously. Tere is therefore an increasing interestin electrifcation of industrial processes in order to achieve long-term decarbonisation g
All cities face a pressing challenge - how can they provide economic prosperity and social cohesion while achieving environmental sustainability? In response, new collaborations are emerging in the form of “urban living labs” (ULL) - sites devised to design, test and learn from social and technical innovation in real time. ULL are proliferating rapidly across cities internationally as one means th
This conclusion presents some closing thoughts on concepts discussed in the preceding chapters of this book. The book focuses on understanding the ways in which Urban living labs (ULL) are being designed and how they vary between urban contexts. It provides conceptually informed and empirically rich examples of the interface between existing social context modes of organisation and urban pri
All cities face a pressing challenge - how can they provide economic prosperity and social cohesion while achieving environmental sustainability? In response, new collaborations are emerging in the form of urban living labs - sites devised to design, test and learn from social and technical innovation in real time. The aim of this volume is to examine, inform and advance the governance of sustaina
Urban experimentation has gained traction in cities all over the world as a way to find new, more sustainable ways to plan and develop cities. Interventions designed to address a diverse range of urban challenges bring innovative social and technical components together to learn by doing. Seen through this lens, the modernist planning that dominated the urban arena for much of the twentieth centur
Extracting microanatomical information beyond the image resolution of MRI would provide valuable tools for diagnostics and neuroscientific research. A number of mathematical models already suggest microstructural interpretations of diffusion MRI (dMRI) data. Examples of such microstructural features could be cell bodies and neurites, e.g. the axon's diameter or their orientational distribution for
