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Pathogenic variants of human CDC14A (cell division cycle 14A) are associated either with nonsyndromic deafness DFNB32 or HIIMS, hearing impairment infertile male syndrome. The 623-residue CDC14A protein has two globular domains (residues 17-152 and 217-325) and a 278-residue C-terminal intrinsically disordered region (IDR). To date, 16 recessive variants of human CDC14A are associated with hearing

While fiscal policy making in the EU is in the hands of national governments, it is to be carried out in accordance with commonly agreed rules: the Stability and Growth Pact (SGP). The SGP originates in the understanding that uncoordinated fiscal policy produces cross-border effects that can harm the functioning of the Economic and Monetary Union. For member states with an excessive deficit, that

Background: Collider bias is often considered a potential explanation when the association between obesity and disease diagnosis differs from that with disease outcome, as seen in the “obesity paradox.” For prostate cancer (PCa), in particular localized PCa, an “inverse” obesity paradox has been observed, where body mass index (BMI) is negatively associated with diagnosis (hazard ratio [HR] ~0.9 p

This is the first part of a work devoted to the study of the set of integer solutions to a system of inequalities determined by homogeneous forms. According to the heuristics that the number of such solutions should match the volume of the set of real solutions, sharp estimates for the volume of the semialgebraic domain under consideration are established. These estimates are expressed as a functi

Introduction: Familial risk of lung cancer (LC) is at the level of many common cancers (ca 2.0) but as cigarette smoking is the main cause of LC, it has remained undefined to what extent smoking contributes to the familial risk. We take advantage of the natural experiment of divorce. In Sweden, it has been customary that children stay with their mother after divorce. We thus hypothesize that only

An important step in understanding the formation and evolution of the nuclear star cluster (NSC) is to investigate its chemistry and chemical evolution. Additionally, exploring the NSC’s relationship to the other structures in the Galactic center and the Milky Way disks is of great interest. Extreme optical extinction has previously prevented optical studies, but near-IR high-resolution spectrosco

Since 2002, Swedish higher education institutions have been mandated by the Higher Education Act to actively promote widening participation. However, there is no national definition of widening participation, leaving each institution to define its own objectives. This article investigates how teachers at Lund University in Sweden understand and implement widening participation, examining their perSince 2002, Swedish higher education institutions have been mandated by the Higher Education Act to actively promote widening participation. However, there is no national definition of widening participation, leaving each institution to define its own objectives. This article investigates how teachers at Lund University in Sweden understand and implement widening participation, examining their per

What is nationalism? When did it originate and how did it develop throughout the centuries? What types of nationalism have evolved in different sociopolitical settings and why? By addressing these questions, this entry seeks to address the key issues of the conceptualization of nationalism, followed by an analysis of its development in different structural, cultural, and political contexts. The en

Hybrid photon counting detectors have significantly advanced synchrotron research. In particular, the introduction of large cadmium telluride-based detectors in 2015 enabled a whole new range of high-energy X-ray measurements. This article describes the specifications of the new PILATUS4 cadmium telluride detector and presents results from prototype testing for high-energy powder X-ray diffraction

Anthropomorphic activities have a large impact on ecosystems in many ways, one of which is how animals behave. Non-motorised nature recreation is a popular human activity of which the impacts on nature are largely unknown. These activities, which include hiking, biking, pet walking and horseback riding, tend to increase during the commencement of the breeding activity for most passerine forest bir

Young adults presenting with knee pain, instability, or both after twisting the knee during sports or at work are commonly seen in primary care. If the symptoms and injury history correspond with suspicion of a torn anterior cruciate ligament (ACL) or meniscal injury, sometimes in combination with positive findings on magnetic resonance imaging, patients are often referred for surgical treatment.

Public and scientific interest in human-robot interactions is growing rapidly. As artificial intelligence (AI) becomes an integral part of human experience, there is an urgent need to understand people’s receptivity to it, especially in emotionally intimate or private spheres. Intimate receptivity goes beyond general technology attitudes, carrying potential implications for companionship, mental h

Although groundwater serves as the predominant source of drinking water across many rural regions and certain urban areas of Rwanda, little is known about this resource. Anthropogenic impacts, such as faecal contamination, as well as geogenic water quality problems, including elevated arsenic, fluoride, iron, and manganese, are among the issues of concern for groundwater quality in Rwanda. Long-te

Background: Although physiological reflux is seen in nearly all newborns to varying degrees, symptoms can be severe and cause gastroesophageal reflux disease (GERD). In preterm infants, one symptom that is often attributed to GERD is apnea and associated cardiorespiratory events, such as bradycardia and oxygen desaturation. Although the relationship between GERD and apnea, bradycardia, and desatur

Turbulent heat transfer over rough surfaces is crucial in natural and industrial processes, yet it has received less attention than that of momentum transfer. Recently, research in this field is rapidly growing, driven by advancements in computational methods, the role of surface roughness in meteorology, and the growing use of Additive Manufacturing technologies for energy and thermal management