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Asthma and chronic rhinosinusitis with nasal polyps (CRSwNP) or without (CRSsNP) are chronic respiratory diseases. These two disorders often co-exist based on common anatomical, immunological, histopathological, and pathophysiological basis. Usually, asthma with comorbid CRSwNP is driven by type 2 (T2) inflammation which predisposes to more severe, often intractable, disease. In the past two decad
Detta kapitel introducerar queera perspektiv på global politik med utgångspunkt i en diskussion om politisk mobilisering kring hbtq-frågor på nationell och transnationell nivå. Att diskutera global politik utifrån ett queerperspektiv handlar inte enbart om att ”lägga till” hbtq-personer. Snarare innebär en queer analys att kritiskt granska vissa av de antaganden kring säkerhet, makt och förtryck s
Energy from buildings accounts for almost 40% of global energy-related carbon emissions. A way to reduce both energy consumption in buildings as well as their environmental impact is to use bio-based insulation materials such as cellulose, wood or hemp fiber insulation. Experiences from modern buildings built with a timber-frame structure and insulated with bio-based materials show that these buil
Detta arbete har utvärderat hastighetssäkrade åtgärders effekt på landsbygdsvägar genom att filma totalt 34 olika sådana åtgärder i södra Sverige och studera hastigheten av frigående bilar och tunga fordon när de passerar de olika åtgärderna.Varje plats har filmats med drönare och alla fordon har automatiskt spårats m.h.a. videoanalys. Därefter har frigående fordon identifierats och deras hastighe
Aims/hypothesis: Islet autoimmunity may progress to adult-onset diabetes. We investigated whether circulating odd-chain fatty acids (OCFA) 15:0 and 17:0, which are inversely associated with type 2 diabetes, interact with autoantibodies against GAD65 (GAD65Ab) on the incidence of adult-onset diabetes. Methods: We used the European EPIC-InterAct case–cohort study including 11,124 incident adult-onse
The stomatopod is a fascinating animal that uses its weaponized appendage dactyl clubs for breaking mollusc shells. Dactyl clubs are a well studied example of biomineralized hierarchical structures. Most research has focused on the regions close to the action, namely the impact region and surface composed of chitin and apatite crystallites. Further away from the site of impact, the club has lower
We propose studying the structure of the χc1(3872) axial vector meson through its γL∗γ→χc1(3872) transition form factor. We derive a light-front wave function representation of the form factor for the lowest cc¯ Fock state. We found that the reduced width of the state is well within the current experimental bound recently published by the Belle Collaboration. This strongly suggests a crucial role
Background: Dosimetry in radionuclide therapy often requires the calculation of average absorbed doses within and between spatial regions, for example, for voxel-based dosimetry methods, for paired organs, or across multiple tumors. Formation of such averages can be made in different ways, starting from different definitions. Purpose: The aim of this study is to formally specify different averagin
Purpose:The objective of the paper is to explore the relationship among perceived quality value, hedonic value, social value, price value, customer engagement and customer-based brand equity using stimulus-organism-response (S-O-R), customer engagement and customer-perceived value theories for digital payment apps. In addition, the study examines the mediating role of customer engagement between c
Aims: Internal and external triggers affect seasonal and circadian variations of myocardial infarction (MI). We aimed to assess sex differences in the common triggers of MI. Methods and results: A nationwide, retrospective, cross-sectional postal survey study was conducted. Individuals who experienced a MI during holidays and weekdays were identified through the SWEDEHEART registry. Twenty-seven p
Markers of downstream events are a key component of clinical trials of disease-modifying therapies for Alzheimer's disease. Morphological metrics like cortical thickness are established measures of atrophy but are not sensitive enough to detect amyloid-beta (Aβ)- related changes that occur before overt atrophy become visible. We aimed to investigate to what extent diffusion MRI can provide sensiti
Increasing tourist use of public transport is a potentially significant means of reducing greenhouse gas emissions. There are limited theoretically informed studies that focus on domestic tourist use of public transport, particularly in an Asian cultural context (e.g. South Korea). To bridge the research gap, this study applies and tests an extended value-attitude-behaviour (EVAB) theory, includin
Myanmar’s economy has been affected by numerous internal and external shocks since 2020. This report takes stock of the effect of these shocks on Myanmar’s workers and their well-being using a reliable new source of household data. The report compares employment indicators from 2017 and 2022 to spotlight the extent of adversity faced by workers and households. Employment indicators for 2017 are ba
The aim of this study was to produce an eco-innovative gluten-free bread with a pleasant taste and a unique formulation that includes the highest quality grains and pseudocereals (buckwheat; rice; and millet); and okara; a by-product of soy milk production. The mixture of pseudocereal and cereal flour contained buckwheat flour 45%, rice flour 33%, and millet flour 22%. Three gluten-free breads; ea
In Parkinson’s disease, there is an accumulation of α-synuclein (SYN) aggregates in neurons, which is promoted by neuroinflammation. In neural cells, cytokine-induced SYN aggregation is modulated by heparan sulfate (HS) derived from glypican-1 (GPC1) by amyloid precursor protein (APP) and nitric oxide (NO)-dependent cleavage. We have explored possible interplay between APP, GPC1, and SYN in undiff
Background: Green environments have been shown to be important for health, although less is known about what, in the environment and the individual, leads to interaction and promotes engagement in activities. Aim: To explore some individuals’ perceptions of their green neighbourhood environment and how the interaction with it promotes engagement in activities. Material and methods: A qualitative a
