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Background: Prostate-specific membrane antigen (PSMA) is an important target for positron emission tomography (PET) with computed tomography (CT) in prostate cancer. In addition to overexpression in prostate cancer cells, PSMA is expressed in healthy cells in the proximal tubules of the kidneys. Consequently, PSMA PET is being explored for renal functional imaging. Left and right renal uptake of P
Sveriges tillväxt i förhållande till utvecklingen i vår omvärld uppvisar tre faser under de senaste 170 åren. Från 1890 till 1950 hade Sverige högre tillväxt än jämförbara länder. Sedan följde en fas med eftersläpning till omkring sekelskiftet 2000. Marknadshämmande regleringar av det finansiella systemet var en huvudorsak till eftersläpningen. Efter den finansiella avregleringen börjar en tredje
Non-polar and semi-polar III-nitrides have beneficial properties for various electronic applications such as light emitting diodes and photodetectors due to the elimination or reduction of polarization effects. However, cost-effective manufacturing of non-polar and semi-polar III-nitride films with sufficient film quality is not feasible yet. We report an investigation of the morphological and str
Objective: To analyze the outcomes of urgent/emergent endovascular aortic repair of patients with free/contained ruptured thoracoabdominal aortic aneurysms (rTAAA). Background: Endovascular repair of rTAAA has been scarcely described in emergent setting. Methods: An international multicenter retrospective observational study (ClinicalTrials.govID:NCT05956873) from January 2015 to January 2023 in 6
The current classification of diabetes had its genesis over 85 years ago, when individuals with diabetes were first subclassified into insulin sensitive and insulin insensitive states based on the response to an oral glucose tolerance test. About 35 years later, the contemporary classifications of type 1 and type 2 diabetes were coined. Today's evidence, however, suggests that multiple etiologic a
Aims: Improved dietary habits are important for successful secondary prevention after myocardial infarction (MI), with counselling and support on healthy dietary habits constituting a cornerstone of cardiac rehabilitation (CR). However, there is limited knowledge on how to optimize CR organization to motivate patients to adopt healthy dietary habits. We aimed to explore associations between CR pro
Objective: Cushing's disease (CD) is associated with severely impaired quality of life and shortened life expectancy. Little is known about the socioeconomic consequences of CD and their impact on long-term outcome. Methods: This was a nationwide study including 371 patients with CD (76% women), diagnosed between 1991 and 2018, and 4 matched controls per patient from the background population. Cli
Gamma-ray bursts (GRBs) are intense, short-lived bursts of gamma-ray radiation observed up to a high redshift (z ∼ 10) due to their luminosities. Thus, they can serve as cosmological tools to probe the early Universe. However, we need a large sample of high-z GRBs, currently limited due to the difficulty in securing time at the large aperture telescopes. Thus, it is painstaking to determine quickl
We introduce a method to enable Hamiltonian Monte Carlo (HMC) to simulate from mixed continuous and discrete posterior distributions. In particular, we show how the "Gumbel Max Trick" and the Concrete (Gumbel-softmax) distribution can be used for constructing a continuous approximation of a categorical distribution, and how this distribution can be efficiently implemented for HMC. We also illustra
During the Last Glacial Period (LGP), Greenland experienced approximately 30 abrupt warming phases, known as Dansgaard-Oeschger (D-O) events, followed by cooling back to baseline glacial conditions. Studies of mean climate change across warming transitions reveal indistinguishable phase offsets between shifts in temperature, dust, sea salt, accumulation, and moisture source, thus preventing a comp
Sociological approaches to culture are divided into interpretive, representational, and embodied perspectives, each grounded in distinct ontologies and causal logics derived from realism and interpretivism. This article aims to bridge embodied and representational approaches and their concomitant philosophies of science. It proposes a concept of meaning-making that unifies representational approacSociological approaches to culture are divided into interpretive, representational, and embodied perspectives, each grounded in distinct ontologies and causal logics derived from realism and interpretivism. This article aims to bridge embodied and representational approaches and their concomitant philosophies of science. It proposes a concept of meaning-making that unifies representational approac
Aquaglyceroporins are channels that facilitate the flux of glycerol and water across lipid bilayers. Although structural information is available for several aquaglyceroporins, the details of how water and glycerol selectivity are maintained and how protons are excluded remain elusive. An approach to obtaining data on the hydrogen atom positions is to apply neutron macromolecular crystallography.
Aims: More than 90% of patients with left bundle branch block (LBBB) and reduced left ventricular (LV) ejection fraction have LV dyssynchrony and a high probability of response to cardiac resynchronization therapy (CRT). A subgroup of patients with non-specific intraventricular conduction delay (IVCD) have a LBBB-like LV activation pattern when studied using invasive mapping and advanced echocardi
The regional variety of actors is considered a key determinant in the last decade's rich literature on the geography of eco-innovation and green regional development. However, little is known about the extent to which regions differ in their specialization in new and established eco-innovation actors. In this article, we propose a regional typology based on green specializations concerning both in
Background and hypothesis: KDIGO recommends proteinuria <1 g/d as a treatment target in patients with immunoglobulin A nephropathy (IgAN) because of high risk of progression to kidney failure. However, long-term kidney outcomes in patients with low-grade proteinuria remain insufficiently studied. Methods: We enrolled patients with biopsy-proven primary IgAN from the Swedish Renal Registry and anal
