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Migratory dendritic cells expressing CD103 are the targets for mucosal vaccines. These belong to either of two lineage-restricted subsets, cDC1 or cDC2 cells, which have been linked to priming of functionally distinct CD4 T cells. However, recent studies have identified plasticity in cDC2 cells with overlapping functions with cDC1 cells, while the converse has not been reported. We genetically eng
The diffraction endstation of the NanoMAX beamline is designed to provide high-flux coherent X-ray nano-beams for experiments requiring many degrees of freedom for sample and detector. The endstation is equipped with high-efficiency Kirkpatrick-Baez mirror focusing optics and a two-circle goniometer supporting a positioning and scanning device, designed to carry a compact sample environment. A rob
Purpose To describe nurse anesthetists’ experiences using smart glasses to monitor patients’ vital signs during anesthesia care. Methods Data was collected through individual semi-structured interviews with seven nurse anesthetists who had used smart glasses, with a customized application for monitoring vital signs, during clinical anesthesia care. Data was analyzed using thematic content analysis
Anaesthetic technique for open surgery of acute distal for arm fracture in adults/elderly is not well defined. Regional anaesthesia, general anaesthesia or a combined general and regional block may be considered. General anaesthetic technique, the timing and drug/drug combination for the regional block must also be considered. This is a study around published studies assessing anaesthtic technique
Purpose: Smart glasses are a kind of wearable technology that gives users sustained, hands-free access to data and can transmit and receive information wirelessly. Earlier studies have suggested that smart glasses have the potential to improve patient safety in anesthesia care. Research regarding health care professionals' views of the potential use of smart glasses in anesthesia care is limited.
Rationale, aims and objectives: Many surgical procedures are nowadays performed as ambulatory or short stay procedures, reducing hospital length of stay. Patient safety and quality of care remain imperative especially when adopting enhanced recovery pathways. Patients should be adequately informed and prepared prior to admission. Recovery is to a major extent dependent after discharge on self-careRationale, aims and objectives: Many surgical procedures are nowadays performed as ambulatory or short stay procedures, reducing hospital length of stay. Patient safety and quality of care remain imperative especially when adopting enhanced recovery pathways. Patients should be adequately informed and prepared prior to admission. Recovery is to a major extent dependent after discharge on self-care
Single nucleotide polymorphisms (SNPs) in various genes have been shown to associate with COPD, suggesting a role in disease pathogenesis. Sulfatase modifying factor (SUMF1) is a key modifier in connective tissue remodelling, and we have shown previously that several SNPs in SUMF1 are associated with COPD. The aim of this study was to investigate the association between SUMF1 SNPs and advanced
Introduction: Allergic asthmatics with both an early (EAR) and a late allergic reaction (LAR) following allergen exposure are termed ‘dual responders’ (DR), while ‘single responders’ (SR) only have an EAR. Mechanisms that differentiate DR from SR are largely unknown, particularly regarding the role and phenotypes of neutrophils. Therefore, we aimed to study neutrophils in DR and SR asthmatics. Met
The issue of how to fulfil people’s needs and participation rights through deliberatively supported decision-making is a central issue in capacity law. In this chapter, I describe and discuss the inter-relationships between autonomy, capacity, and social services for persons with dementia in long-term home-based care in Sweden. Some of the points raised may apply equally to other groups with cogni
Memories may integrate elements experienced in different events. For instance, meeting a woman leaving her house, and later meeting another woman entering the same house, may allow us to infer that the two women live together. Such memory representations are thought to rely on integrative encoding mechanisms, allowing us to make inferences about the world and generalize knowledge to entirely new s
ObjectivesThe formation of episodic memories is critically determined by how we visually sample the world over time via sequences of eye movements. Nonetheless, in the neuroscience of human memory, memory encoding has almost exclusively been studied in experimental paradigms where the study material is presented in a single fixed location on the screen, and where eye movements are treated as artif
Episodic memory enables mental time travel, allowing us to relive specific, personally experienced events tied in time and place. This feat of human memory is considered to be dependent on the reinstatement of the cortical patterns that were active at the time of encoding. A growing body of recent literature has provided support for this idea by showing that retrieval success co-varies with the ne
First-generation migrants tend to have better health than those of native ancestry, while second-generation migrants often are affected by negative health assimilation. Less is known about immigrants arriving before their teens, the 1.5 generation, or those with one native and one immigrant parent, the 2.5 generation. We apply logistic regression models to study physical and mental health outcomes
Introduction: Housing shortage due to population growth within metropolitan areas, combined with an ageing population, has put pressure on current housing provision in Sweden. Thus, there is an urgent need to develop sustainable housing policies to accommodate the growing number of seniors in accessible home environments. This study aimed to gain an in-depth understanding of how municipalities cur
BackgroundAccessible housing is crucial to maintain a good quality of life for older adults with functional limitations, and housing adaptations are instrumental in resolving accessibility problems. It is unclear to what extent older adults, who have a high risk of further functional decline, use housing adaptation grants acquired through the long-term care (LTC) insurance systems. This study aime
Måltidskulturer påverkar alla situationer där lagande, ätande ochdrickande förekommer. Trots detta tas måltidskulturella aspektersällan i beaktande i det praktiska arbetet med professionella måltideri Sverige. Med en ökad kunskap om måltidskultur är det möjligt attdesigna måltider som tilltalar och skänker mening till gäster medolika bakgrund, ideal och preferenser. Det finns därför en storpotenti
In this paper, we analyze one of the early welfare interventions in the Swedish welfare state targeted towards mothers and young children: the introduction of a child day-care system. Because quantitative research on day-cares in historical settings is generally scarce, in this study, we focus on the determinants of day-care enrollment in southern Sweden during the early twentieth century. We use
