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IntroductionBreast cancer is a heterogeneous disease in which imaging plays a central role. Beyond identifying malignancy, imaging provides information about the mammographic tumor appearance, breast density, and characteristics of the surrounding adipose tissue, which may reflect underlying tumor biology and relate to the prognosis. The aim of this thesis was to explore how features from mammogra
Randomised controlled trial (RCT) protocols contain essential details needed to understand and evaluate the trial's planned aims, design, data collection methods, monitoring, data analysis, and participants' safety. However, key information is often omitted from paediatric RCT protocols, including details on dose adjustments of interventions based on age, body surface area, or weight; developmenta
In medieval Scandinavia, parchment was a crucial writing material for everything from property deeds and judicial matters to religious works and account keeping. As society became more and more invested in literacy, the demand for parchment grew. However, the supply of animals for parchment could not increase to the same extent without great changes in animal husbandry. This thesis explores how me
This study analyzes the temporal evolution of the short-term P-wave morphological variability (PWMV) within the one-hour interval immediately preceding the onset of atrial fibrillation (AF) episodes. This PWMV is hypothesized to be an index of vulnerable atrial substrate, allowing to identify instability increases preceding the AF episode onset. We analyzed 32 ambulatory ECG recordings from subjec
How is sustainable development translated in higher education institutions (HEIs)? This study examines how sustainable development has been translated within the ‘policy world’ of HEIs, focusing on one research-intensive university in Sweden. Sustainable development, widely introduced into legislation in 2003, required HEIs to develop policies addressing sustainability. At one faculty at the resea
This reflective commentary, based on long-term experience in UK higher education, proposes a novel approach to using a wicked problem model to develop policy and practice within higher education. The aim of this approach is to reframe the narrative of strategic development to acknowledge the complexity of cultural change and the importance of stakeholder consultation to build trust, moving away fr
Background: Normal hand function relies on a finely tuned interaction between the sensory and motor systems within the central and peripheral nervous systems. The central nervous system continuously adapts to changed activity, environmental changes, learning, and injury — a phenomenon known as neuroplasticity. The neuroplasticity is a life-long ability and presents opportunities for therapeutic in
Decarbonising the built environment is essential to mitigating the climate crisis, as buildings significantly contribute to greenhouse gas emissions. Adaptive reuse presents a sustainable alternative to demolition and new construction. This study evaluated the Global Warming Potential (GWP) of an adapted building through renovation and operation across three scenarios, compared to a reference scen
The impact of the COVID-19 pandemic on building energy use has been studied across various countries. However, with the growing trend toward flexible working and the rising frequency of climate-induced extreme weather events, the combined effects of these factors on future energy use remain largely unexplored. This study develops a methodology to investigate the resilience of the UK's low-income h
Crustaceans inhabit a wide variety of habitats, from the open ocean to ephemeral pools. Within these habitats, crustaceans play key roles as herbivores, detritivores, and predators, and interact with competitors ranging from conspecifics to other crustaceans to diverse assemblages of invertebrates. As with most communities and ecosystems, efforts to understand the impacts of crustacean community d
Purpose of review – Small cell lung cancer (SCLC), particularly its transdifferentiated form, is highly aggressive and has a poor prognosis. The diagnosis of SCLC transdifferentiation is challenging, as repeat biopsies are often not clinically feasible and few noninvasive predictors of this neuroendocrine transformation have been identified to date. Recent findings – Some retrospective studies and
Cross-laminated timber (CLT) is increasingly used for construction of multi-storey buildings. However, ensuring satisfactory vibro-acoustic performance, particularly in the low-frequency range (typically below 200 Hz), remains a significant challenge, often necessitating add-on solutions such as floating floors. In this study, the aim was to investigate how vibration levels for CLT panels can be r
Studies of the Silurian sequence on Gotland have significantly advanced our understanding of Silurian climate dynamics, with much of the research focusing on small outcrops and short cores. Gotland has an extensive network of abandoned oil and gas wells. Most of these include gamma-ray well logs, which have not yet been fully utilised for their stratigraphic value. While the Ordovician succession
