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Purpose: Cyclin D1 has a central role in cell cycle control and is an important component of estrogen regulation of cell cycle progression. We have previously shown that high cyclin D expression is related to aggressive features of ER-positive but not ER-negative breast cancer. The aims of the present study were to validate this differential ER-related effect and furthermore explore the relationsh
We used a southern Swedish cohort of psoriasis (PSO) and psoriatic arthritis (PsA) patients and population-based referents (N = 57,800) to investigate the influence of socioeconomic and demographic factors on the probability of healthcare use and on healthcare costs when controlling for need as measured by PSO/PsA and common additional morbidities such as diabetes, depression and myocardial infarc
Objective: Patients with limited metastatic and locally advanced bladder cancer have a poor prognosis, and no definite treatment recommendations exist. However, long-term survival is possible for selected patients if surgery is combined with multiple courses of chemotherapy (i.e. induction chemotherapy). Patients with tumours that are insensitive to chemotherapy probably have little to gain from s
The main thesis of this chapter is that children do not learn single new words but rather new words that belong to the same domain. For example, once they learn a word for a color, other color words will be learned soon after. The chapter presents a model of such domain-oriented language learning. Conceptual spaces are used as a framework for modeling the semantic processes involved in language ac
Background: To investigate the risk of first-time acute coronary syndrome (ACS), stroke and venous thromboembolism (VTE) in patients with ankylosing spondylitis (AS), psoriatic arthritis (PsA) and undifferentiated spondyloarthritis (uSpA), compared to each other and to the general population (GP). Methods: This is a prospective nationwide cohort study. Cohorts with AS (n = 6448), PsA (n = 16,063)
Abstract: Recent developments in radiotherapy have focused on the management of patient motion during treatment. Studies have shown that significant gains in treatment quality can be made by ‘gating’ certain treatments, simultaneously keeping target coverage, and increasing separation to nearby organs at risk (OAR). Motion phantoms can be used to simulate patient breathing motion and provide the m
This research makes clear the narrative transformation in a novel called Red Rebel by Ali Ahmad Bakathir after dealing with a systematic an entrance in which he explains what is meant by narrative transformation and how it is implemented in the text of novels through presenting a number of concepts provided by the narrative semiotics by the School of Paris. The first part of this research s
The qualitative division between domain-general and domain-specificcognition is unsubstantiated. The distinction is instead betterviewed as opposites on a gradual scale, which has more explanatorypower and fits current empirical evidence better. We also argue thatcausal cognition may be more general than social learning, which itoften involves.
The ability to draw other agents’ attention to objects and events is an important skill on the critical path to effective human-robot collaboration. People use the act of pointing to draw other people’s attention to objects and events for a wide range of purposes. While there is significant work that aims to understand people’s pointing behavior, there is little work analyzing how people interpret
‘Public moods’ are often referred to in laymen’s accounts of public reactions to social events, yet the concept has rarely been invoked by social scientists. Taking public moods seriously as an analytical concept, this article relies on recent work on the moods of individuals as a means of exploring the moods of the public. To be in a certain mood is to attune oneself to the situation in which one
This volume presents a series of case studies that trace the ways in which audiences across Europe have attempted to return to Pompeii by emulating its interior decorations since the city’s rediscovery in the mid-eighteenth century. As such, it is about both the impact of Pompeian antiquity on the present and the reception in the present of that antique past, exploring the variety of ways in whichThis volume presents a series of case studies that trace the ways in which audiences across Europe have attempted to return to Pompeii by emulating its interior decorations since the city’s rediscovery in the mid-eighteenth century. As such, it is about both the impact of Pompeian antiquity on the present and the reception in the present of that antique past, exploring the variety of ways in which
