Sökresultat

Filtyp

Din sökning på "*" gav 559198 sökträffar

Carcinoma of the parotid Gland : A Population-Based study of incidence and treatment outcomes in 1018 patients

Intro: Population-based studies predominantly focused on carcinoma of the parotid gland (CPG) are rare. The study aims were to analyze the incidence of CPG and to assess treatment outcomes in relation to histopathology, preoperative diagnosis and adjuvant radiotherapy. Methods: A retrospective analysis was conducted on data from the Swedish Head and Neck Cancer Register (SweHNCR), including 1,018

Shared e-scooters as a commuting mode : evidence from Malmö, Sweden

Shared e-scooters (SEs) are increasingly integrated into urban mobility systems, yet their role in commuting and contribution to sustainable transport remain insufficiently understood. This study examines SE commuting patterns in Malmo, Sweden, focusing on their use as both a first-/last-mile connection to public transport and a primary commuting mode. Using pre-pandemic trip data from a major SE

Digital quantification of stroma percentage enhances prognostic stratification in pancreatic cancer

Background: Pancreatic ductal adenocarcinoma (PDAC) is characterized by a prominent desmoplastic stroma, which plays a crucial role in tumor biology and treatment resistance. While the stromal compartment is a defining histopathological feature of PDAC, its prognostic significance remains incompletely understood. This study aimed to quantify the stromal content in PDAC using digital pathology and

The bladder trigone : A sensory organ?

The bladder trigone is a distinct anatomical and functional subregion of the urinary bladder, defined by its triangular configuration between the ureteral orifices and the internal urethral orifice. Although traditionally less studied compared to the bladder dome and detrusor body, recent morphological, molecular, and transcriptomic analyses reveal that the trigone is highly specialized. Understan

Prothrombin concentrations in middle-aged men and women – stability over time and correlations with cardiovascular risk factors

Background Prothrombin is a vitamin K-dependent glycoprotein synthesized in the liver and circulating in blood as an inactive zymogen. The corresponding activated thrombin enzyme is a central player in hemostasis and thrombosis. Still, little is known about the individual variation over time of the prothrombin concentration in plasma in the general population. Objectives This study aimed to establ

The role of metabolic syndrome in osteoarthritis development : Is obesity the key driver?

Objective: Investigate the role of metabolic syndrome and obesity in incident osteoarthritis (OA). Methods: Prospective cohort study with up to 11 years follow-up. From a general population cohort of 28,786 individuals from Sweden aged 45 to 75, we selected individuals without OA diagnosis and without joint pain during the year prior to the baseline. Metabolic syndrome was defined at baseline by t

In-situ NAP-XPS reveals water-induced phase segregation of MoS2 nanoparticles in hydrodeoxygenation catalysis

Hydrodeoxygenation (HDO) is a catalytic process applied for the reduction of oxygen levels in hydrocarbons from bio-derived feedstock as part of the processing into renewable fuel. The MoS2-based hydrotreating catalysts, currently being applied for the HDO reaction, are exposed to a complex environment consisting of O-rich hydrocarbons and water, which adversely impacts the state and stability of

The succinate prodrug NV354 prevents brain lesions and late-stage motor dysfunction in mitochondrial complex I deficiency

Leigh syndrome is a fatal pediatric neurodegenerative disease caused by mitochondrial dysfunction, which can be modeled in the Ndufs4 KO mouse with mitochondrial respiratory chain complex I (CI) deficiency. This study explores NV354, a prodrug of succinate with enhanced oral bioavailability and brain uptake, as a potential therapy to counteract this devastating condition. NV354 modulated whole-bod

Hagiography of the Macedonian Period and Symeon Metaphrastes

The chapter examines the flourishing hagiographical production during the Macedonian age, a period marked by intense rewriting of earlier Greek hagiography. This rewriting culminated in the Metaphrastic menologion, compiled by Symeon Metaphrastes in the late tenth century. Following the end of the iconoclastic controversy until Symeon, a clear progression is attested from an initial monastic inter

A daily diary study of cancer-related pain and associated difficulties: The role of psychological flexibility

Introduction: Chronic pain is among the most common side effects of cancer in cancer patients and survivors, often co-occurring with fatigue, emotional distress and elevated fears of cancer recurrence. Both pain and the associated difficulties are associated with poorer outcomes. Longitudinal studies are needed that identify psychosocial factors that mitigate the effects of chronic cancer-related

Tailoring structural, electrical, and magnetoelectric properties of BiFeO3 ceramics via low-level cobalt substitution

This study presents a comprehensive investigation of the structural, microstructural, electrical, magnetic, and magnetoelectric properties of low-level substitution of Co3 + for Fe3+ ions in the perovskite B-site of BiFeO3 (BiFe1−xCoxO3, x = 0.01, 0.015 and 0.02). X-ray diffraction combined with Rietveld refinement confirms the retention of the rhombohedral R3c structure across all compositions, w

Solubility and Metastability of the Amyloidogenic Core of Tau

Intracellular deposits of neurofibrillary tau tangles and extracellular Aβ plaques are closely associated with Alzheimer’s disease. The mapping of thermodynamic parameters, including solubility limits, indicates when a protein forms amyloid fibrils or remains in solution. This reveals the direction of change of the system and may help in understanding drift and steady states in living systems. Her

The benefits of digital travel information for informal transport : Insights from app users in Cochabamba, Bolivia

This study provides an in-depth analysis of the impact of a multimodal journey-planning app on users of informal public transport systems in Cochabamba, Bolivia. We analyze survey data (N=648) collected through the Trufi Association NGO's digital travel app on changes in mobility behavior, satisfaction, and everyday life improvements. Participants report more frequent use of informal transport (49

A global map of groundwater-dependent vegetation in the Mediterranean biome

Groundwater-dependent vegetation (GDV) plays a vital role in maintaining biodiversity and ecosystem services in the Mediterranean biome but is increasingly threatened by climate and land use change. Large-scale GDV mapping in arid regions is critical for effective conservation and water resource management but remains challenging due to limited ground-truth data and the lack of high-resolution rem

Carbon Credits in a Just Transition: Justice Implications of Scotland's Carbon Credit Schemes

Den skotska regeringen har åtagit sig att genomföra en rättvis omställning till en klimatneutral ekonomi till år 2045. En viktig del av klimatarbetet inkluderar restaurering av natur, för att minska utsläpp av växthusgaser och öka upptag i koldioxidsänkor. Regeringen driver för ökade privata investeringar i restaurering av natur, genom bland annat generering av kolkrediter. Denna studie syftar tilThe Scottish Government has committed to achieving a just transition to a net-zero economy by 2045. As part of its decarbonisation strategy, it has promoted private investment in nature-based solutions through the development of carbon credit schemes. This thesis examines the extent to which carbon credit schemes in Scotland – specifically the Peatland Code and the Woodland Carbon Code – support a

Trans* parenthood & « doing family »: Understanding parenthood in practices

Trans parenting, scarcely explored in scientific literature, is often treated through the lens of accessibility to procreation technology, state of legislation or experiences of family continuity. A “doing family practice” approach allows us to explore how trans parenthood is conceived in actions for trans parents in France. Through narrative interviews, a “doing family” approach to parenthood, an