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Men with germline breast cancer 1, early onset (BRCA1) or breast cancer 2, early onset (BRCA2) gene mutations have a higher risk of developing prostate cancer (PCa) than noncarriers. IMPACT (Identification of Men with a genetic predisposition to ProstAte Cancer: Targeted screening in BRCA1/2 mutation carriers and controls) is an international consortium of 62 centres in 20 countries evaluating the
During 2012 - 2013 a study to evaluate conventional X-ray procedures and patient doses in Klintzi and Novozibkov areas of Bryansk region, Russia, was conducted. X-ray operation parameters included quality assurance of equipment, collection of procedure parameters and clinical practice evaluation. Effective doses were calculated for each selected procedure and dose distributions were established. 7
The technology of today, with the use of computers and the Internet, has enabled new types of map usage. Screen maps provide possibilities that could never be offered by standard paper maps, and allow maps to be integrated into information services. Mobile map services are information services adapted to mobility; using small screen presentation devices and communication networks to access various
Information on mortality in ankylosing spondylitis (AS) is scarce. Our study therefore aimed to assess: (1) mortality in AS versus the general population, and (2) predictors of death in the AS population.
Objective. Formal joint assessments are critically important to improve rheumatological care of patients with RA. The aim of this study was to determine the usefulness of patient-recorded 28 tender joint counts (TJCs) and swollen joint counts (SJCs) using a tablet personal computer and to explore the possibility of using patient-recorded data to calculate 28-joint DAS (DAS-28) and EULAR response.
The introduction of Rituximab has greatly improved therapeutic options for patients with B-cell non-Hodgkin lymphoma (B-NHL). However, a substantial fraction of patients with aggressive B-NHL fails first-line therapy, and most patients with relapsing indolent B-NHL eventually acquire Rituximab resistance. Molecular understanding of the underlying mechanisms facilitates the development of pharmacol
The aim of the present study was to evaluate the effectiveness of microsurgical varicocele repair in patients with grade III lesions and chronic dull scrotal pain.
Combining cultural theory with the philosophy of law, this essay argues that the advent of state-managed, industrial genocide has brought about a crisis of confidence in the institutions of modern society. A wave of incrimination emanates from the holocaust, which primarily strikes against the institutions of law, but also affects the credibility of sociosymbolic mandate as such. Drawing on the wr
OBJECTIVES: The aim of this study was to examine whether three main definitions of the metabolic syndrome (MetS) - WHO, National Cholesterol Education Program-Adult Treatment Panel III and International Diabetes Federation - identify the same individuals and are able to predict incident myocardial infarction (MI) in families with essential hypertension. METHODS: The tested definitions were prospec
