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Community-aqcuired pneumonia (CAP) is one of the most common infectious causes leading to hospitalization. Historically, Streptococcous pneumoniae has been the most common etiology in CAP and has therefor led to targeted interventions such as immunization in children, the elderly, and risk groups. Other important pathogens are Haemophilus influenzae, Mycoplasma pneumoniae and respiratory viruses.T
AIM: Risk assessment tools for periodontitis lack sufficient precision to predict disease progression. The aim of this exploratory study was to evaluate proteolytic activity (PA) in gingival crevicular fluid in relation to clinically assessed progression risk, microbial community composition and host proteome.MATERIALS AND METHODS: Samples were collected from 109 patients with periodontitis and st
Background: Dietary vitamins play a role in antioxidant defense and immunoregulation. However, prospective studies exploring the association between vitamin intakes during pregnancy and the child’s risk of type 1 diabetes are limited. Objectives: This population-based prospective cohort study aimed to investigate the association between maternal intake of vitamins A, C, D, and E during pregnancy a
Jewelry design is a complex and craft-based practice involving diverse activities, processes, and interactions with a range of actors to create jewelry that meets clients’ individual needs. However, how jewelry design, as a practice, is carried out is not very well described and, therefore, is not fully understood. Investigating how designers manage their work, what inspires them, how they relate
Objective: We investigated the risk for alcohol use disorder (AUD) and drug use disorder (DUD) in the offspring of parents with major depression (MDD) or bipolar disorder (BD), including how parent and offspring sex impact familial transmission. Method: Offspring born in Sweden during 1970–1990 in intact families with parental MDD or BD (n = 1,218,920) were examined using Swedish population regist
The upcoming revision of the Energy Performance of Buildings Directive (EPBD) will require reporting of the whole life-cycle global warming potential (GWP) for new buildings from 2028 at the European level. In the Nordic countries, several frontrunners have already introduced national climate declaration requirements for new buildings. The focus was primarily on embodied emissions from building ma
Background: Characterizing the immune landscape of thymic epithelial tumors (TETs) is essential for patient stratification for emerging immunotherapeutic approaches and for optimizing follow-up strategies. In this study, we examined the expression patterns and clinical significance of five immune-related markers in a large cohort of TETs. Material and methods: Expression of TIM3, OX40L, GTF2I, XPO
When the dimensions of structures shrink to the order of the inelastic mean free path of the energy-carrying quasi-particles, the character of energy transport changes from diffusive to ballistic. However, the point of transition remains a matter of debate. Here, we leverage the fluence-dependent transport efficiency to distinguish ballistic and diffusive electron transport in an approach not rely
Social epidemiologists frequently aim to quantify how social, spatial, or organizational contexts shape individual outcomes, an aim commonly addressed through the use of multilevel models. These models readily estimate the magnitude of group-level differences, but it is more difficult to formalize the uncertainty in the relative ordering of predicted group-level outcomes, which is often considered
Intermittent hypoxia (IH), the defining physiological feature of obstructive sleep apnea, has been strongly linked to cardiovascular morbidity, yet the early myocardial effects of short-term IH remain poorly characterized. In this study, we investigated whether brief IH exposure elicits adaptive anti-apoptotic signaling or early injurious activation of intrinsic apoptotic pathways in the murine he
We demonstrate that the weak gravity conjecture (WGC) and the Festina-Lente conjecture (FLC) yield novel bounds on any hypothetical fifth force and millicharged particles (mCPs), as well as on the scale of inflation and on the effective Higgs quartic interaction. In particular, we find that combining the FLC with inflation leads to stronger bounds on mCPs than what the simple application of the FL
The United Nations and European Union have set ambitious conservation goals to halt and reverse declines in biodiversity by protecting 30% of land and sea areas by 2030. Effective conservation planning requires evidence-based spatial prioritization to maximize the coverage of species within designated protected areas. Based on a pan-European database for occurrence and abundance of breeding birds
Pancreatic islets of Langerhans are central to the pathogenesis of all major forms of diabetes. The ability to study human islets ex vivo has advanced our understanding of diabetes and aided in the development of novel therapeutics. However, for decades, very few laboratories had access to this critical resource and experiments on human islets were typically underpowered. More recently, multiple c
For more than a decade, stem cells have been on the horizon as a future treatment for Parkinson's disease (PD) and with this vision, it is anticipated that this novel treatment approach may be a paradigm shift in treating PD. The field has progressed enormously during the past few years and several clinical phase I/IIa trials using human embryonic stem cells or induced pluripotent stem cells as so
Söderåsens nationalpark är ett populärt område för friluftsliv på grund av den vidsträckta bokskogen. Bokskogen har också ett stort vetenskapligt intresse på grund av dess dynamiska historia under de senaste seklerna. Enligt Rundgren et al. (2025) var boken väletablerad fram till mitten av 1700-talet då dess utbredning minskade för att sedan börja öka igen under mitten av 1800-talet. Detta baseradSöderåsen National Park is a popular recreational area due to its extensive beech forest. The beech forest is also of great scientific interest because of its dynamic history in recent centuries. According to Rundgren et al. (2025), the beech was well established until the mid-18th century when its abundance decreased markedly, followed by an expansion from the mid-19th century. It is based on pal
Detta examensarbete undersöker hur industriella kulturmiljöer i rurala landskap kan transformeras till nya offentliga miljöer utan att förlora sin rumsliga identitet, materiella närvaro eller historiska tyngd. Projektet tar sin utgångspunkt i Borgeby Tegelbruk vid Lödde å, där det öppna jordbrukslandskapet möter en storskalig industristruktur präglad av repetitiva trästommar, långa rumsliga sekvenThis thesis investigates how industrial heritage in rural landscapes can be transformed into new public environments without losing their spatial identity, material presence, or historical depth. Situated along the Lödde River in the open agricultural landscape of southern Sweden, the project takes Borgeby Tegelbruk as its point of departure, a former brickworks whose large-scale timber structures
