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Chromosome abnormalities, in particular translocations, and gene fusions are hallmarks of neoplasia. Although both have been recognized as important drivers of cancer for decades, our knowledge of the characterizing features of the cytobands involved in recombinations is poorly understood. The present study, based on a comparative analysis of 10 442 translocation breakpoints and 30 762 gene fusion

Background and purpose National guidelines for treatment of distal radius fractures (DRFs) were presented in Sweden in 2021. In the guidelines, a fast-track is recommended for 4 subgroups of highly unstable DRFs. Regardless of the results of the closed reduction these are recommended for surgery within 1 week of injury. This study aims to evaluate the potential consequences of the newly presented

Maritime archaeological investigations of the wreck of the medieval warship Gribshunden (1495), flagship of King Hans of Denmark and Norway, have revealed diverse artifacts including exotic spices imported from far distant origins: saffron, ginger, clove, peppercorns, and almond. The special circumstances of the vessel's last voyage add unique context to the assemblage. Gribshunden and an accompan

Complex diseases are caused by a combination of genetic, lifestyle, and environmental factors and comprise common noncommunicable diseases, including allergies, cardiovascular disease, and psychiatric and metabolic disorders. More than 25% of Europeans suffer from a complex disease, and together these diseases account for 70% of all deaths. The use of genomic, molecular, or imaging data to develop

This article deals with the impact of certain retail strategies on urban life. More specifically it deals with two recent tendencies of the retail environment: (a) spatial homogenisation and clustering of retail into large areas or territories, and (b) the synchronisations of retail with different kinds of public activities and events. For the last decades, retail areas have tended to grow larger

Popular Abstract in Swedish Det finns tre typer av makromolekyler som är grundläggande för allt liv på jorden: DNA, RNA och proteiner. I varje cell i kroppen finns en kopia av vår arvsmassa, DNA. Denna består av gener som avkodas först till RNA och sedan till tiotusentals proteiner. Alla gener är inte aktiva i varje cell eller i varje tidpunkt. Proteiner kontrollerar nästan alla aspekter av det vi

A Relative Success? Notes on the circulation and wider reception of Scandinavian Crime In this paper Scandinavian crime, or Nordic Noir, in its filmic and televisual incarnations, will be considered on its relative merits as a transnationally successful, but regionally based popular cultural expression. The inquiry will be conducted against a backdrop which briefly traces the history and some of t

Background All hospital laboratories in Sweden use the Owren prothrombin time (PT) method primarily to monitor anticoagulant treatment. Direct international normalized ratio (INR) calibration was introduced in 1999 under the supervision of Equalis, the national organization for external quality assessment (EQA) in laboratory medicine. Objectives We present 25 years of combined experience in develo