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LUPE - The Lund Perfusion Program

LUPE is a modular software for calculation of brain perfusion parametric maps from dynamic susceptibility contrast perfusion weighted MR images.   Source code and a runtime version (.sav file) are published here under the terms of the GPL. See the overview below for more info. Overview   News: Latest version is 1.2. See the modules page for changes and additions. Included is now a 11-page user gui

https://www.msf.lu.se/research/mr-physics-group/software/lupe-lund-perfusion-program - 2026-04-23

Effects of muscular dystrophy, exercise and blocking activin receptor IIB ligands on the unfolded protein response and oxidative stress

Protein homeostasis in cells, proteostasis, is maintained through several integrated processes and pathways and its dysregulation may mediate pathology in many diseases including Duchenne muscular dystrophy (DMD). Oxidative stress, heat shock proteins, endoplasmic reticulum (ER) stress and its response, i.e. unfolded protein response (UPR), play key roles in proteostasis but their involvement in t

Expression, activity, and subcellular localization of testicular hormone-sensitive lipase during postnatal development in the guinea pig

The present work reports on testicular hormone-sensitive lipase (HSL), the biological significance of which has been documented in male fertility. The HSL protein levels and enzymatic activity were measured, respectively, by densitometry of immunoreactive bands in Western blots, performed with antibodies against recombinant rat HSL, and by spectrophotometry in seminiferous tubules (STf) and inters