Blood and CSF Biomarkers in Amyotrophic Lateral Sclerosis: Diagnostic and Prognostic Insights from a Systematic Review and Meta-analysis
Aims: Identifying reliable biomarkers is crucial for addressing diagnostic uncertainty and prognostic stratification in amyotrophic lateral sclerosis (ALS). This systematic review and meta-analysis aimed to integrate recent evidence on blood and cerebrospinal fluid (CSF) biomarkers.Methods: We searched studies published between January 1, 2019, and March 25, 2025, investigating blood or CSF biomar
