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Background: Previous reports from relatively small clinical cohorts have suggested that the clinical presentation of obstructive sleep apnea (OSA) differs between men and women. Objective: We aimed to explore sex differences in clinical and polysomnographic features of OSA in a large nationwide registry. Methods: Participants from the ongoing Turkish Sleep Apnea Database (TURKAPNE) Study from 34 c
Rationale: There is no consensus on criteria to include in an asthma remission definition in real life. Factors associated with achieving remission after biologic initiation remain poorly understood. Objectives: To quantify the proportion of adults with severe asthma achieving multidomain-defined remission after biologic initiation and identify prebiologic characteristics associated with achieving
Introduction Despite an increasing amount of research related to gender-affirming treatment (GAT) outcomes among transgender and gender-diverse (TGD) people (ie, people who experience discomfort or distress in the misalignment between their gender and sex assigned at birth) in recent years, the evidence base for current recommendations is suboptimal. One contributing factor is the heterogeneity in
Background: The 313-variant polygenic risk score (PRS313) provides a promising tool for clinical breast cancer risk prediction. However, evaluation of the PRS313 across different European populations which could influence risk estimation has not been performed. Methods: We explored the distribution of PRS313 across European populations using genotype data from 94,072 females without breast cancer
Atmospheric inverse modelling and ecosystem data assimilation are two complementary approaches to estimate CH4 emissions. The inverse approach infers emission estimates from observed atmospheric CH4 mixing ratio, which provide robust large scale constraints on total methane emissions, but with poor spatial and process resolution. On the other hand, in the ecosystem data assimilation approach, the
Mild traumatic brain injury (mTBI) is a frequent but underreported consequence of professional cycling crashes, yet current helmet testing standards primarily simulate head-first impacts, and their representation of real-world head impact scenarios is unclear. This study explores crash typology of professional cycling crashes involving head-ground contact through systematic video analysis of 128 h
Introduction: Present literature on professionalism usually focuses on individual parts of professional identity development and mostly, as these are seen and are evaluated by the dental educators. When looking at professionalism and in particular professional identity formation, It is extremely important to listen to the voice of the students regarding their thoughts, attitudes, beliefs and ideas
PURPOSE – Comparative studies demonstrate that patients who use electronic patient-reported outcomes (ePROs) experience better outcomes; however, research comparing ePRO designs to determine optimal strategies for routine clinical practice is limited. We aimed to determine the impact of a novel checkbox format for presenting items in a postoperative symptom-assessment ePRO tool.METHODS – Patients
Purpose Despite increased interest in opioid-free strategies, their clinical uptake remains limited. This study explores Swedish perioperative healthcare professional’s (HCPs) knowledge, attitudes, and practices regarding opioid and nonopioid analgesia across intraoperative and postoperative contexts. Design A national web-based survey was conducted among perioperative HCPs across Sweden between O
Purpose: Electronic patient-reported outcomes (ePROs) are used postoperatively to detect complications through real-time symptom monitoring. This study examines whether alerts triggered through the “Recovery Tracker” (RT), an ePRO system, predict 30-day re-admission or re-operation after lumpectomy. Methods: We retrospectively reviewed breast cancer patients who underwent lumpectomy at a single in
BACKGROUND: Sepsis-induced coagulopathy (SIC) is a scoring system developed for early detection of coagulopathy in sepsis and selection of patients for interventional studies. Our aim was to define the prevalence of SIC in a critically ill population and investigate if SIC at intensive care unit (ICU) admission is associated with morbidity and mortality.METHODS: Patients admitted with septic shock
OBJECTIVE: The objective of this study was to provide novel comparative insights on the contributions of injury deaths to the changes in sex gaps in life expectancy (SGLE) and sex gaps in life disparity (SGLD) across Nordic countries.STUDY DESIGN: Retrospective demographic analysis of aggregated mortality data.METHODS: To compute life expectancy (LE)/life disparity (LD), annual data on age- and se
The CHaracterising ExOPlanet Satellite (CHEOPS) is a partnership between the European Space Agency and Switzerland with important contributions by 10 additional ESA member States. It is the first S-class mission in the ESA Science Programme. CHEOPS has been flying on a Sun-synchronous low Earth orbit since December 2019, collecting millions of short-exposure images in the visible domain to study e
Ice hockey is a high-intensity sport with high rates of concussions and musculoskeletal injuries. To manage pain, players may (over) use nonsteroid anti-inflammatory drugs (NSAIDs) which can have adverse health effects. In 2022, the Swedish Women's Elite League (SDHL) became the first women's league to introduce body checking, potentially increasing injury risks and NSAID use. This study examines
Background: Apical hypertrophic cardiomyopathy (ApHCM) is a distinct variant of hypertrophic cardiomyopathy (HCM). Few studies have focused on the genetic determinants of this subtype. We aimed to investigate the genetic basis of apical hypertrophy in a Swedish cohort. Methods–Results: Longitudinal data on 58 unrelated index patients with ApHCM from the Southeast healthcare region in Sweden from 2
Context. HR 10 has only recently been identified as a binary system. Previously thought to be an A-type shell star, it appears that both components are fast-rotating A-type stars, each presenting a circumstellar envelope. Although showing complex photometric variability, spectroscopic observations of the metallic absorption lines reveal variation explained by the binarity, but not indicative of de
