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In this book, Metzinger develops a theory of pure consciousness, while presenting empirical findings from more than 500 experiential reports from practitioners of meditation. Pure consciousness is what we experience when we attend to awareness itself – when attention is refocused to the normally unnoticed medium through which we experience the world. The practice of meditation is likely to facilit

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Biological tissues are complex, dynamic and inherently three-dimensional systems whose physiological and anatomical organization is shaped by their native structural and molecular context. Recent advances in three-dimensional and label-free imaging are transforming our ability to interrogate complex biological specimens across molecular, cellular, and organ scales. However, many conventional imagi

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How did colonial fiscal systems respond to economic crisis, and what were the distributional consequences of those responses? This paper examines fiscal policy and inequality in the Gold Coast during the Great Depression using newly reconstructed tax revenues and expenditure data linked to social tables. It estimates the tax burden relative to income, the sectoral incidence of taxation, and the re

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Tiden tas ofta för given. Men de sätt på vilka den uppfattas och uttrycks är aldrig neutrala eller förutbestämda – de är resultatet av specifika erfarenheter, kunskaper och önskningar. Mot bakgrund av konkurrerande värderingar och förväntningar på den boreala skogen i ljuset av klimatförändringar och resurspåfrestningar undersöker denna avhandling hur förståelser, erfarenheter och tolkningar av tiTime is often taken for granted. However, the ways in which it is perceived and expressed are never neutral or pre-given - they are the result of particular experiences, knowledges and desires. In the context of competing values and expectations for the boreal forest in the face of climate change and resource pressures, this thesis investigates how understandings, experiences and framings of time

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Post-growth science seeks to meet human needs equitably for all within the planet’s ecological limits, independent of GDP growth [1]. We propose that developing sector-specific post-growth visions, for example, in healthcare, energy, food, housing, education, or recreation, can help translate post-growth principles into concrete and relatable futures. Communicating such visions can broaden public

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We study the relationship between the structural transformation of the economy and the income distribution, focusing on the case of Sweden from 1870 to 1970, with extra attention paid to the 1870–1950 period, for which we produce extensive new data. Average income increased fivefold between 1870 and 1950, and the share employed in agriculture declined from 72 to 23 per cent. To study the evolution

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With osteoarthritis progression, both mechanical and structural changes of articular cartilage occur. However, little is known about the interaction between the two. Digital volume correlation (DVC) could theoretically provide such insight, extracting the internal strain field from computed tomography (CT) datasets of the tissue under load. A recent study highlighted the possibility of time-resolv

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BACKGROUND: Atrial fibrillation (AF) burden is associated with adverse outcomes; in some patients, very low AF burden may not be actionable.OBJECTIVE: This study aimed to model AF burden as a function of monitoring time without AF.METHODS: We included 11,639 US patients (median age 62 years [interquartile range 46‒73], 40.6% male) without permanent/persistent AF, monitored for ≥14 days in 2021 wit

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The efficient clearance of IAPP oligomers (IAPPo) by autoantibodies is crucial as increased plasma levels of IAPPo can induce microvascular alterations and Alzheimer's disease (AD)-characteristic amyloid-β deposition in the brain. We have recently demonstrated that plasma immunoglobulin (Ig) A levels against IAPPo, but not IgG, are reduced in an Apolipoprotein E (APOE) ε4 allele dose-dependent man

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BACKGROUND: Clinical practice guidelines are intended to help with decision-making. However, their quality differs. Guidelines of low quality are a waste of resources and can cause patient harm. We compared the quality of the Danish, Norwegian, and Swedish guidelines on papillary thyroid cancer (PTC) with those of the American Thyroid Association (ATA, 2015 version).METHODS: Three pairs of apprais

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Malignant ventricular arrhythmias (VAs) are a major contributor to mortality in myocardial infarction. Although early revascularization has markedly reduced the incidence of late and secondary VA, the occurrence and fatality rates of VA during the prehospital stage remain high. In ST-segment elevation myocardial infarction, most VAs occur within the first 24 hours, with only a small proportion obs

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Pilar leiomyoma is a rare benign tumour that derives from the arrector pili muscle. Due to its rarity, the dermatoscopic features of pilar leiomyoma are scarcely reported in the literature. Herein, we report a further case of pilar leiomyoma that highlights its dermatofibroma-like dermatoscopic features and underscores that, despite advances in noninvasive imaging technologies, histopathology rema

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This paper analyses the effects of innovation policy on innovation output. We use a database of Swedish innovations (1970-2001), linked to both approved and non-approved public funding projects, and combine logistic regressions with matching approaches. We address: (1) the characteristics of firms applying for public funding, (2) the effects of public funding on the generation of significant innov

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AIMS: Assessment of mitral valve (MV) function and haemodynamics is essential for optimizing surgical repair in children with mitral regurgitation. Patient-specific fluid-structure interaction (FSI) modelling can capture the complex interplay between valvular mechanics and blood flow. In this study, we apply a patient-specific FSI framework to evaluate MV function and haemodynamics in paediatric p

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BACKGROUND: During the last decade chemotherapy recommendations have changed for patients with pancreatic adenocarcinoma (PDAC) as novel regimens demonstrate better survival in selected cohorts. Herein we aim to, in a regional cohort, analyse therapy changes and possible survival benefits over a 10-year period.METHODS: Patients in the southern region of Sweden diagnosed with pancreatic cancer betw