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Huntington's disease (HD) is a progressive neurodegenerative disorder, and increasing evidence suggests that inflammation, both central and peripheral, plays a role in disease progression. Neurohistology and neuroimaging studies illustrate neuroinflammatory processes as part of HD pathophysiology. Furthermore, studies of blood and cerebrospinal fluid from HD patients show altered levels of inflamm
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Context. According to the well-established hierarchical framework for galaxy evolution, galaxies grow through mergers with other galaxies. The ΛCDM cosmological model predicts that the stellar halos of massive galaxies are rich in remnants resulting from minor mergers. Stellar Streams Legacy Survey (SSLS) has provided a first release of a catalogue with a statistically significant sample of stella
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New extragalactic measurements of the cloud population-averaged star formation efficiency per free-fall time, Ïμff, from PHANGS show little sign of a theoretically predicted dependence on the gas virial level and weak variation with cloud-scale gas velocity dispersion. We explore ways to bring theory into consistency with the observations, particularly by highlighting systematic variations in inte
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The inclusion of the knowledge and perspectives of Indigenous peoples and local communities (IPLC) in global sciencepolicy processes are increasingly being mandated. This is indicative of the recognition of their expertise and worldviews to inform social and ecological decisions. The IPBES Values Assessment (VA) explicitly highlighted the necessity for a nuanced engagement of different actors whil
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Huntington's disease (HD) is a fatal neurodegenerative disorder characterized by progressive motor, cognitive, and psychiatric symptoms. Research efforts to understand and treat the disease have historically focused on neuronal pathology, but growing evidence underscores the critical role of oligodendrocytes in its pathogenesis. This review synthesizes recent findings on oligodendroglial dysfuncti
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We report the first observation of a momentum-resolved superconducting gap in the Hg-based trilayer cuprate, which holds the highest record of superconducting transition temperature (T_{c}) at ambient pressure. By angle-resolved photoemission spectroscopy utilizing a microfocused beam, clear quasiparticle dispersions originating from the inner and outer CuO_{2} planes (IP and OP, respectively) wer
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Among the most advanced techniques for quality control, image processing and optical methods areprominent because of their precision and versatility. These methods often involve analyzing specklesgenerated by coherent laser illumination because coherent light provides detailed and accuratemeasurement capabilities. In speckle metrology-based techniques, the accurate measurement ofspeckle displaceme
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Quantum instruments describe both the classical outcome and the updated state associated with a quantum measurement. We ask whether these processes can be simulated using only a natural subset of resources, namely projective measurements on the system and quantum processing of the postmeasurement states. We show that the simulability of instruments can be connected to an entanglement classificatio
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This article explores how collaboration across Arctic borders has enabled the emergence of ultrasmall, Indigenous-led sectors, examining the development of Indigenous screen industries in Sápmi and Kalaallit Nunaat (Greenland). The Sámi film industry has experienced a notable rise, driven by strategic transnational collaborations and the establishment of institutions such as the International Sámi
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Pulmonary fibrosis remains a devastating and often fatal condition due to the lack of effective treatments that halt disease progression. Rodent models of pulmonary fibrosis are crucial to identify candidate targets and novel therapeutic agents. However, the attrition rate of novel drug candidates in clinical trials remains high. This review suggests complementing traditional methods used to evalu
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Background: Drug-related problems are common in older individuals. A medication reconciliation has the goal of identifying and maintaining an accurate medication list and can serve to prevent drug-related problems caused by discrepancies. Objectives: This study aimed to explore primary care physicians’ intentions towards performing medication reconciliation in patients with multimorbidity using a
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BACKGROUND: Wolff-Parkinson-White (WPW) syndrome is a rare cardiac disorder that predispose to supraventricular arrhythmias. Prognosis is usually benign, yet there is an increased lifetime risk of sudden death. While typically sporadic, familial clustering has been reported. This study aimed to assess the risk of WPW, arrhythmias, and mortality among siblings of individuals with WPW.METHODS: This
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Over the last two decades, the social identity of the jihadist has become a central part of street culture. Depictions of jihadists can be found in popular music, movies and media reports. Propaganda celebrating or condemning jihadism circulates online, and a significant number of individuals with a background in street crime have flirted with or converted to jihadism. Drawing on ethnographic fiel
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This brief anthology begins with a basic outline of the interdisciplinary course Smart City Governance – AI Ethics in a Spatial Context, given at LTH, Lund University. Three selected student essays from the class of 2024/2025 then follow. These demonstrate the topics possible to analyse when combining engineering students from programmes on data, ICT, architecture, and land surveying with students
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Biological membranes and human interfaces are maintained under non-equilibrium conditions, where they are constantly exposed to different stimuli. The aim of this work is to advance our knowledge of human interfaces and evaluate how they respond to stimuli they naturally encounter, such as fluctuations in external humidity conditions, temperature, or UVB irradiation. In the first part of this thes
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Insect wing interference is highly sensitive to the membrane thickness and has shown remarkable potential to differentiate insect species, both ex vivo in laboratory settings and for free-flying insects in situ. While several studies have reported diversity of wing interference patterns, no study has linked this resonant coherent scattering from membranes to the goniometric scattering phase functi
