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Time-of-flight neutron transmission and diffraction measurements were performed on four solid beryllium metal grades using the HIPPO neutron time-of-flight diffractometer equipped with an energy-resolved neutron imaging detector at Los Alamos National Laboratory. Analysis of the extracted total neutron cross sections from the transmission measurements revealed a reduction in the coherent elastic s

Galectin-3 (Gal3) is a multifunctional lectin expressed and released by microglia, where it influences diverse processes in both homeostasis and disease. To dissect its intracellular and extracellular roles, we generated Gal3-deficient BV2 microglial cells and systematically assessed how genetic deletion and exogenously added recombinant Gal3 shape microglial physiology. Gal3 deletion increased ce

This review examines how coordination is infrastructured in digital health ecosystems where technologies, institutions, and practices intersect across organisational and professional boundaries. Drawing on a systematic analysis of the literature, we identify three interdependent infrastructural layers: technological, informational, and institutional, and four recurring processes through which coor

Hepatitis B virus (HBV), hepatitis delta virus (HDV), and hepatitis C virus (HCV) remain leading drivers of chronic viral hepatitis, cirrhosis, hepatocellular carcinoma, and liver-related mortality. This ESCMID Study Group for Viral Hepatitis (ESGVH) narrative review summarizes recent advances and expert perspectives in the field. For HBV, emerging biomarkers such as quantitative HBs antigen, HBV

BACKGROUND: – The clinical use of risk scores to guide treatment decisions and improve clinical outcomes has rarely been prospectively evaluated. This study aimed to evaluate whether a biomarker-based ABC-AF risk score–guided multidimensional treatment strategy improves long-term outcomes in patients with AF. METHODS: – The multicenter, registry-based, randomized, controlled, open-label study enro

Background: The 2015 Lancet Commission on global surgery identified surgery and anaesthesia as indispensable parts of holistic health-care systems. However, COVID-19 exposed the fragility of planned surgical services around the world, which have also been neglected in pandemic recovery planning. This study aimed to develop and validate a novel index to support local elective surgical system streng

Hexavalent chromium (Cr(VI)) is classified as a Group 1 human carcinogen and increases the risk of lung cancer because it can generate reactive oxygen species, induce DNA damage, and trigger epigenetic alterations Occupational Cr(VI) exposure can occur during different work processes, but when this PhD study was initiated, the exposure level to Cr(VI) at Swedish workplaces and its health risk were

Denna bok ger ett helhetsperspektiv över hur redovisning används i samband med värdering av och kreditgivning till företag. I boken presenteras metoder för beräkning och analys av ett stort antal nyckeltal baserade på redovisning.Vi lyfter även fram de faktorer som kan påverka redovisningens användbarhet samt hur det praktiskt kan gå till att bedöma kvalitet i redovisning. Boken ger läsaren kunska

Aim: Urinary tract infection (UTI) is the most common and significant complication after voiding cystourethrography (VCUG) but the reported incidence in children varies highly. Therefore, the aim of this study was to evaluate the rate and possible risk factors for UTIs after VCUG. Method: A multicentre retrospective cohort study of children < 15 years of age undergoing VCUG between 2017 and 2022 w

Digital transformation of healthcare has largely been conceptualised throughadoption-centric lenses, relying on “barriers and facilitators” frameworks thatfocus primarily on individual technology adoption or organisational factors.Yet transformation in practice depends on sustained coordination amongmultiple autonomous actors who must align their actions across organisational,professional, and tec

Universities have long used internationalization to prepare students for a highly interconnected world. Although internationalization has often been associated with mobility, current calls for equity, diversity, and inclusion, and climate consciousness, among other things, require institutions to change this strategy. As a response, curriculum internationalization emerges as a more inclusive and s

Background and purpose — Computed tomography (CT) has become a valuable tool for preoperative planning and perioperative, real-time navigation during total hip arthroplasty (THA). CT can also quantify postoperative implant migration without the need for implanted bone markers, making it a promising alternative to the current gold standard radiostereometric analysis (RSA). Our aim was to evaluate t

Downfolding Methods in Many-Electron Theory is a comprehensive description of the last 30 years of study in this field, starting from LDA+U to LDA+DMFT and arriving at the recent work on multitier self-consistent GW+EDMFT. It focuses on different levels of first-principles electronic structure theories for strongly correlated electrons and outlines the downfolding method as a general approach-prov

We present a method to calculate neutron scattering cross sections for deformed nuclei using many-body wave functions described with multiple reference states. Nuclear states are calculated with the generator coordinate method using a low energy effective Hamiltonian. Using these states, a nonlocal and energy dependent optical potential is consistently constructed, allowing one to directly investi

Silk fibres derive their exceptional properties from hierarchical protein organisation, yet the molecular pathways that guide this structural transformation remain poorly resolved. During regenerated silk fibroin gelation under biomimetic gradual acidification, we identify a stepwise assembly pathway comprising nanoscale clustering, domain growth within clusters, and mesoscale network formation. T

Microalgae emit volatile organic compounds (VOCs) that can profoundly impact climate by leading to new particle formation and influencing clouds. Among these VOCs, dimethyl-sulphide (DMS) is of particular interest due to its key role in atmospheric processes. Despite its importance, many detailed processes linking microalgae and sea-atmosphere interactions remain poorly understood. We investigated

This introductory essay explains the motivation behind this collection and provides summaries of the individual contributions to this volume. Bernard Williams is often regarded as a merely negative or critical philosopher, with no distinctive philosophical approach of his own. This perspective ignores Williams’s efforts to make positive contributions to several areas in ethics and metaethics, incl

This chapter provides an overview of the different optical sectioning methods that enable performing three dimensional (3D) imaging of possibly complex samples. It discusses their benefits and limitations regarding their penetration depth, their imaging speed, their photo-toxic effect or their complexity. Focusing on fluorescence imaging, the chapter dives into approaches that make it possible to