Sökresultat

This work studied a metal fluoride transition state analogue (TSA) complex of β-phosphoglucomutase (βPGM), a phosphoryl transfer enzyme catalysing the interconversion of glucose-6-phosphate (G6P) and glucose-1-phosphate (G1P), and its P146A and A136N mutants using advanced NMR spectroscopy methods. Conformational exchange rates of βPGM:MgF3–:G6P TSA complex were extracted at a grid of temperatures

Detta examensarbete tillämpar en kvalitativ fallstudieansats för att utforska hur digitalisering omformar modeindustrins värdekedjor – en bransch präglad av globalt fördelad produktion, korta produktlivscykler och växande hållbarhetskrav. Ett analytiskt ramverk utvecklas genom att integrera Porters värdekedjeperspektiv, Fords typstrategier för teknologi, Rayport och Jaworskis perspektiv på kundgrä

Per- and polyfluoroalkyl substances (PFAS) are becoming an important regulatory and tech-nical concern for the pharmaceutical industry due to their high environmental persistence, po-tential health risks, broad use across many industrial production fields and growing pressure for their regulation in consumer products. The pharmaceutical industry is particularly at risk for PFAS, due to their stric

Advanced therapy medicinal products (ATMPs) are complex biological products that present specific scientific and regulatory challenges during clinical development. This thesis aimed to analyse consolidated Part I considerations raised during assessment of investigational ATMP clinical trial applications (CTAs) under the Clinical Trials Regulation (CTR) to identify recurring scientific and regulato

Title: Exploring Rush Order Policies in a Multi-Echelon Inventory System Authors: Stina Nilsson & Lina Solbu. Supervisors: Johan Marklund, LTH. Philip Mårtensson & Johan Lidvall, Volvo Group. Background: The Case Company is currently transitioning their inventory control from a single-echelon to a multi-echelon optimization approach. As no formal rush order policy currently exists, it i

Syftet med det här examensarbetet är att undersöka hur musiklärare och deras handlingsutrymme påverkas av olika ramfaktorer i kulturskolan. Det berör faktorer som byggnadens konstruktion och arkitektoniska förutsättningar, gehör från ledning, chefer och rektorer samt graden av spatial kompetens hos musiklärarna. Semistrukturerade intervjuer med ett kriteriebaserat urval ligger till grund för uThe purpose of this study is to investigate how the discretionary power varies amongst music teachers based on the different contextual factors in school of arts. The rules of conduct refers to the structure of the building and architectural constraints, the accommodation from managers and principals, and the spatial competence amongst music teachers. The data in this thesis is collected through s

This study aimed to investigate healthcare counselors’ experiences of providing psychosocial support for patients’ relatives and next of kin within different somatic healthcare settings, as well as the organisational conditions influencing this work. Furthermore, the study aimed to examine healthcare counselors’ discretion in relation to family support across different healthcare contexts. The stu

Extreme heat is not neutral. In Athens, the dense urban environment and harsh summer climate disproportionately impact the socio-economically marginalized. This research bridges the gap between climate data and human experience by uniting geospatial and qualitative survey data regarding heatwaves in Athens Municipality, with urban heat island research, vulnerability theory and climate justice. Sat

This master thesis focused on evaluating and designing the user interface of a camera production machine used in an industrial manufacturing environment. The project was conducted in collaboration with a global technology company and aimed to improve usability, clarity and operational support through a user-centered design approach. The work began with a comprehensive pre-study of the existing int

As buildings become more energy-efficient in their operation, the environmental costs of building components, such as carbon emissions during manufacturing, transportation, and end-of-life, are becoming increasingly significant. Automated façade shading systems have been widely proposed for their ability to reduce operational energy use and improve daylight performance. However, their life-cycle e

This thesis examines whether the AI Act and the transparency obligations of its Art. 50(2) and (4) are adequate to effectively address violations of the fundamental rights to privacy and data protection by nonconsensual pornographic deepfakes. To this end, the thesis first demonstrates how nonconsensual pornographic deepfakes infringe the rights to privacy and data protection as enshrined in Art.

Denna masteruppsats har som mål att utvärdera på vilket sätt nivån av presence inom virtuell verklighet (VR) påverkar användares prestation i en miljö när de ut- för uppgifter. Den utvärderar även hur mycket ansträngning som bör läggas för att göra VR-miljöer mer realistiska i forskningssammanhang. Denna studie genom- fördes i två primära delar; först en utvecklingsfas där en gedigen informationss

There exists a lack of laser-based remote sensing methods that give signals with high intensity and directionality. According to previous research, mirrorless lasing can meet these requirements; however, neither the dependence on the gain medium geometry nor the light-matter interaction responsible for the emission has been investigated in detail. This thesis project examined the sideways lasing e

The rapid expansion of the plant-based beverage sector has increased the demand for high-performance, barista-grade oat drinks that are capable of withstanding the thermal and acidic stresses of coffee applications. This master’s thesis, conducted in collaboration with Cerealiq AB, evaluates the efficacy of six specific enzymatic treatments in modifying the structural and physical properties of oa

20-25% of semi-natural habitat per square-kilometre is required for the provision of local Nature’s Contributions to People. Farmers are key actors in reversing the severe habitat deficits in agricultural regions. Conceptually anchored in the Safe and Just Earth System Boundary Framework and the Tripartite Framework for Mitigation Pathways, this thesis combines a systematic literature review on ho

The thesis explores the differences between the enforcement of State aid within the EU compared to the EEA EFTA States, in an effort to find out whether Iceland’s accession to the EU could affect the legal status of power purchase agreements entered into by Iceland’s National Energy Company, Landsvirkjun, and energy-intensive user. These agreements have already been reviewed by the EFTA Surveillan

This thesis analyses the structural limitations of the prevailing entitlement-based framework of international human rights law (IHRL), particularly in pluralistic and multicultural societies, and evaluates whether integrating duties alongside existing rights, a duty-infused reconceptualization, can address those limitations or not? The study draws its primary motivation from a structural crisis i

Cleanrooms in the pharmaceutical industry are energy-intensive environments where HVAC systems account for roughly 50-75% of energy use due to high air changes per hour and strict conditioning requirements for indoor humidity and temperature. This thesis presents a techno-economic analysis comparing two of the most common HVAC system types. These systems are centralized, using one large AHU to pro